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The map label for this gene is phzF [H]

Identifier: 16119869

GI number: 16119869

Start: 67445

End: 68317

Strand: Direct

Name: phzF [H]

Synonym: Atu6056

Alternate gene names: 16119869

Gene position: 67445-68317 (Clockwise)

Preceding gene: 41223325

Following gene: 159161960

Centisome position: 31.48

GC content: 62.08

Gene sequence:

>873_bases
ATGGTCGAACTGGTCGCAGGTCTCATTGATGTCTTCGCAGATGCGCCATTGACCGGCAATCCGCTCGCGGTGGTGCAGGA
CGCCGACGACCTTACCGATGATGCGATGCGGCGGATCGCCGGTGAATTCAATCAGGCCGAGACCACCTTCATACTTCGGA
GCGCACGTGCCGATTGGAAACTGCGGTCGTTCACCGCCAGCGGCGCGGAAGTATTCGGTGCGGGCCACAACGCCCTCGGT
GCGTGGCTTTGGCTAGGAGAACATGGAAATCTCGGTTCGCTGACGACCGCCCGAACCCTTCAGCAGGAGATCGGTCAGGA
TGTTCTTCCGATCGAGCTCGAATTGATCGCCGGCCGCGTCCACGGCCGCATGCTCCAGGCGCCGCTGCGCTTGTCGGACG
CGCTCAGTGATGTCGCGCCTCTCGCCGACGCTCTTGGCCTCGGTCTGGGCGACATTCTGTCAGAACCGGCGCCACGTCCC
GCCGACACCGGTGCGGCTCATCTGATGGTGCGCGTTCGCAATGCCGGCACGGTTGACGAGGCGCGACCCGATGCCGGCAA
GCTGCTCGCCGTTCTGAGAAAGACGGCGGCGGAAGGGTGTTATGTCTATGCGTTCGATGCCGGAGCATCGAACACTGCCT
ACGCCCGGTTCTTCAATCCAACTGTTGGTCTGTGGGAGGATTCGGCGACCGGAACCGCCGCTGGCCCGCTGGCGGCGTAT
CTTGCAGCTACGGGAAACCTCAGGAACAACGAATTGGTGATCGAACAAGGTACCAAGATGGGCCGCCGCAGCATTCTGCA
TATCCGGCTGAAGCCCGAACCGGAACTCTCCGGGACAGGCATTGTCGTGTTGAGAGGCGTGATCCGGCTTTAA

Upstream 100 bases:

>100_bases
TTGAAGCTGAGTAATTTGACTTTTTCTATTTGTATAAGCGGCTGTACAGTGCTGATCGTCAAACCCTATCAAAATAAACT
CATTCAAGGCAGCAGGAAAA

Downstream 100 bases:

>100_bases
TGCTTGCACCCGGTCCTGCGCACGTACCGATCCTTCAAACTTCAGCAAGCCGGCGCTGCGACGTCTCTTGGTTCTGGGGC
GACGACTTTATCGTGCTGCC

Product: phenazine biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MVELVAGLIDVFADAPLTGNPLAVVQDADDLTDDAMRRIAGEFNQAETTFILRSARADWKLRSFTASGAEVFGAGHNALG
AWLWLGEHGNLGSLTTARTLQQEIGQDVLPIELELIAGRVHGRMLQAPLRLSDALSDVAPLADALGLGLGDILSEPAPRP
ADTGAAHLMVRVRNAGTVDEARPDAGKLLAVLRKTAAEGCYVYAFDAGASNTAYARFFNPTVGLWEDSATGTAAGPLAAY
LAATGNLRNNELVIEQGTKMGRRSILHIRLKPEPELSGTGIVVLRGVIRL

Sequences:

>Translated_290_residues
MVELVAGLIDVFADAPLTGNPLAVVQDADDLTDDAMRRIAGEFNQAETTFILRSARADWKLRSFTASGAEVFGAGHNALG
AWLWLGEHGNLGSLTTARTLQQEIGQDVLPIELELIAGRVHGRMLQAPLRLSDALSDVAPLADALGLGLGDILSEPAPRP
ADTGAAHLMVRVRNAGTVDEARPDAGKLLAVLRKTAAEGCYVYAFDAGASNTAYARFFNPTVGLWEDSATGTAAGPLAAY
LAATGNLRNNELVIEQGTKMGRRSILHIRLKPEPELSGTGIVVLRGVIRL
>Mature_290_residues
MVELVAGLIDVFADAPLTGNPLAVVQDADDLTDDAMRRIAGEFNQAETTFILRSARADWKLRSFTASGAEVFGAGHNALG
AWLWLGEHGNLGSLTTARTLQQEIGQDVLPIELELIAGRVHGRMLQAPLRLSDALSDVAPLADALGLGLGDILSEPAPRP
ADTGAAHLMVRVRNAGTVDEARPDAGKLLAVLRKTAAEGCYVYAFDAGASNTAYARFFNPTVGLWEDSATGTAAGPLAAY
LAATGNLRNNELVIEQGTKMGRRSILHIRLKPEPELSGTGIVVLRGVIRL

Specific function: Isomerase that catalyzes the condensation of two molecules of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known [H]

COG id: COG0384

COG function: function code R; Predicted epimerase, PhzC/PhzF homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phzF family [H]

Homologues:

Organism=Escherichia coli, GI1787737, Length=291, Percent_Identity=28.1786941580756, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321818, Length=301, Percent_Identity=25.5813953488372, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003719 [H]

Pfam domain/function: PF02567 PhzC-PhzF [H]

EC number: NA

Molecular weight: Translated: 30668; Mature: 30668

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELVAGLIDVFADAPLTGNPLAVVQDADDLTDDAMRRIAGEFNQAETTFILRSARADWK
CHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHEEEECCCCCCE
LRSFTASGAEVFGAGHNALGAWLWLGEHGNLGSLTTARTLQQEIGQDVLPIELELIAGRV
EEEECCCCHHEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHH
HGRMLQAPLRLSDALSDVAPLADALGLGLGDILSEPAPRPADTGAAHLMVRVRNAGTVDE
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCC
ARPDAGKLLAVLRKTAAEGCYVYAFDAGASNTAYARFFNPTVGLWEDSATGTAAGPLAAY
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHH
LAATGNLRNNELVIEQGTKMGRRSILHIRLKPEPELSGTGIVVLRGVIRL
HHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVELVAGLIDVFADAPLTGNPLAVVQDADDLTDDAMRRIAGEFNQAETTFILRSARADWK
CHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHEEEECCCCCCE
LRSFTASGAEVFGAGHNALGAWLWLGEHGNLGSLTTARTLQQEIGQDVLPIELELIAGRV
EEEECCCCHHEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHH
HGRMLQAPLRLSDALSDVAPLADALGLGLGDILSEPAPRPADTGAAHLMVRVRNAGTVDE
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCC
ARPDAGKLLAVLRKTAAEGCYVYAFDAGASNTAYARFFNPTVGLWEDSATGTAAGPLAAY
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHH
LAATGNLRNNELVIEQGTKMGRRSILHIRLKPEPELSGTGIVVLRGVIRL
HHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8586283; 11497469 [H]