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The map label for this gene is galE [H]

Identifier: 160902525

GI number: 160902525

Start: 1133585

End: 1134571

Strand: Direct

Name: galE [H]

Synonym: Pmob_1064

Alternate gene names: 160902525

Gene position: 1133585-1134571 (Clockwise)

Preceding gene: 160902524

Following gene: 160902526

Centisome position: 52.25

GC content: 34.35

Gene sequence:

>987_bases
ATGATACTTGTTACAGGAGGAGCTGGGTACATAGGTTCTCATTTGGTGAAAAGGCTGCAAGATCAAAATAAAGAAGTAGT
AGTTTTTGATAACTTCGAAAAAGGCCATAGGTGGGCTGTTAAAGATGTACAAGTCGTTGAAGGAGATCTTAGAAACGAAA
AAGACATTGATTACGCTTTTGAAAATTACAAAATAGACGAGGTATATCATTTCGCGGCTTTTTCATTAGTTGGTGAATCC
ATGACAGAACCTAATAAATATTTTAATAACAATATTTGTGGAACATTGAACCTTTTAAAAAACATGCAAAAACATAAATG
TAGATACATAGTTTTTTCTTCTACCGCAGCTGTTTATGGAGAACCAGAAAAAGTCCCCATCACTGAAAATCAACCTAAGA
ATCCTACGAACATCTATGGTCAATCAAAATTAATGATTGAAGATATTCTCAATTGGTATTCTAAACTTGATATTATAAGG
TATGTAGCTTTAAGATATTTCAACGCCGCTGGGGCGTATTATGATGGTAGTATAGGCGAAGCCCACGAACCTGAAACTCA
CTTGATCCCATTAGTTCTTGAAACAGCTTTAGGGAAAAGAGACCAACTGTACGTTTATGGCAATGATTACCCAACCAAGG
ACGGAACAGCCGTTAGAGACTATATCCATGTAATGGATTTGATAGATGCCCATATTTTAGCTATGAAATGGATGAAGGAA
AATGAAAAATCTGACGTTTTTAATTTAGGTAATGGTCAAGGATTTACCGTTTTAGAGGTTATTAAAACAGCTGAAAAAGT
AACTTCAAAAAAAATAAATTACGAAGTAGTAGAAAGAAGGCCTGGTGATCCTGCTGTTTTAATAGCTTCCTCAAAGAAAG
CAGAGGAAGTTTTAAACTGGCACCCTCAAAATAAAGAATTAGAAAAGATAATATCTGATGCATGGAAATGGCATAAAAAT
AAAGACAAAAATGTTTTAGGAGGATAA

Upstream 100 bases:

>100_bases
AAAGAACAGGGACTTTGGAGGCTGGCGGGAAAAGATGAAATATTGGAAGATGGTGAAATATTAAACATTAGAGCTAGCAC
TTGATTTGAGGGGTGACCTA

Downstream 100 bases:

>100_bases
CTCATGGAGATAGTAGACCTAAAAAAATGGATAAGAGATATACCAGATTTTCCAGAAAAAGGAGTTATATTTAGAGATAT
CACACCACTTTTGAAAAACC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MILVTGGAGYIGSHLVKRLQDQNKEVVVFDNFEKGHRWAVKDVQVVEGDLRNEKDIDYAFENYKIDEVYHFAAFSLVGES
MTEPNKYFNNNICGTLNLLKNMQKHKCRYIVFSSTAAVYGEPEKVPITENQPKNPTNIYGQSKLMIEDILNWYSKLDIIR
YVALRYFNAAGAYYDGSIGEAHEPETHLIPLVLETALGKRDQLYVYGNDYPTKDGTAVRDYIHVMDLIDAHILAMKWMKE
NEKSDVFNLGNGQGFTVLEVIKTAEKVTSKKINYEVVERRPGDPAVLIASSKKAEEVLNWHPQNKELEKIISDAWKWHKN
KDKNVLGG

Sequences:

>Translated_328_residues
MILVTGGAGYIGSHLVKRLQDQNKEVVVFDNFEKGHRWAVKDVQVVEGDLRNEKDIDYAFENYKIDEVYHFAAFSLVGES
MTEPNKYFNNNICGTLNLLKNMQKHKCRYIVFSSTAAVYGEPEKVPITENQPKNPTNIYGQSKLMIEDILNWYSKLDIIR
YVALRYFNAAGAYYDGSIGEAHEPETHLIPLVLETALGKRDQLYVYGNDYPTKDGTAVRDYIHVMDLIDAHILAMKWMKE
NEKSDVFNLGNGQGFTVLEVIKTAEKVTSKKINYEVVERRPGDPAVLIASSKKAEEVLNWHPQNKELEKIISDAWKWHKN
KDKNVLGG
>Mature_328_residues
MILVTGGAGYIGSHLVKRLQDQNKEVVVFDNFEKGHRWAVKDVQVVEGDLRNEKDIDYAFENYKIDEVYHFAAFSLVGES
MTEPNKYFNNNICGTLNLLKNMQKHKCRYIVFSSTAAVYGEPEKVPITENQPKNPTNIYGQSKLMIEDILNWYSKLDIIR
YVALRYFNAAGAYYDGSIGEAHEPETHLIPLVLETALGKRDQLYVYGNDYPTKDGTAVRDYIHVMDLIDAHILAMKWMKE
NEKSDVFNLGNGQGFTVLEVIKTAEKVTSKKINYEVVERRPGDPAVLIASSKKAEEVLNWHPQNKELEKIISDAWKWHKN
KDKNVLGG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=40.5325443786982, Blast_Score=247, Evalue=9e-66,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=40.5325443786982, Blast_Score=247, Evalue=9e-66,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=40.5325443786982, Blast_Score=247, Evalue=9e-66,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=28.3387622149837, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7657641, Length=270, Percent_Identity=23.7037037037037, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116268111, Length=267, Percent_Identity=26.9662921348315, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=40.1812688821752, Blast_Score=250, Evalue=9e-68,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790049, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=28.6567164179104, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=37.7581120943953, Blast_Score=214, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=37.5366568914956, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17539532, Length=342, Percent_Identity=27.4853801169591, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17568069, Length=292, Percent_Identity=26.7123287671233, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=40.8284023668639, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=39.8809523809524, Blast_Score=239, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=27.7955271565495, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37483; Mature: 37483

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGYIGSHLVKRLQDQNKEVVVFDNFEKGHRWAVKDVQVVEGDLRNEKDIDYAF
CEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHCCCCCCCCCCHHH
ENYKIDEVYHFAAFSLVGESMTEPNKYFNNNICGTLNLLKNMQKHKCRYIVFSSTAAVYG
HCEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCEEECC
EPEKVPITENQPKNPTNIYGQSKLMIEDILNWYSKLDIIRYVALRYFNAAGAYYDGSIGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
AHEPETHLIPLVLETALGKRDQLYVYGNDYPTKDGTAVRDYIHVMDLIDAHILAMKWMKE
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
NEKSDVFNLGNGQGFTVLEVIKTAEKVTSKKINYEVVERRPGDPAVLIASSKKAEEVLNW
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHCC
HPQNKELEKIISDAWKWHKNKDKNVLGG
CCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MILVTGGAGYIGSHLVKRLQDQNKEVVVFDNFEKGHRWAVKDVQVVEGDLRNEKDIDYAF
CEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHCCCCCCCCCCHHH
ENYKIDEVYHFAAFSLVGESMTEPNKYFNNNICGTLNLLKNMQKHKCRYIVFSSTAAVYG
HCEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCEEECC
EPEKVPITENQPKNPTNIYGQSKLMIEDILNWYSKLDIIRYVALRYFNAAGAYYDGSIGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
AHEPETHLIPLVLETALGKRDQLYVYGNDYPTKDGTAVRDYIHVMDLIDAHILAMKWMKE
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
NEKSDVFNLGNGQGFTVLEVIKTAEKVTSKKINYEVVERRPGDPAVLIASSKKAEEVLNW
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHCC
HPQNKELEKIISDAWKWHKNKDKNVLGG
CCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]