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The map label for this gene is hisC [H]

Identifier: 160902486

GI number: 160902486

Start: 1089055

End: 1090161

Strand: Direct

Name: hisC [H]

Synonym: Pmob_1023

Alternate gene names: 160902486

Gene position: 1089055-1090161 (Clockwise)

Preceding gene: 160902485

Following gene: 160902489

Centisome position: 50.2

GC content: 31.17

Gene sequence:

>1107_bases
TTGAAATTCAACCCAATTTTAGAAAGTTTTGAGGAATACAAACCTTCTAATACTTATATCAACGATGGATTCATAGATCT
CAGCAAAAATGAAAATCCATTCGACCTTTCTTTAGACCTTAAAAAGATCTTTTTCCAAAAGATAACAGAAACAAACATAA
ATCGATACCCCGAATTAACCGCTGACAACATCAGACAAAAAATAGCGACTTTCTTAAACTCATATTTTTCAAGATATAAT
ATAGATCTTGACATGAACAACATAGTGGTGGGTAATGGCAGTGACGAGACGATATCTTACTTGGTTAAAATCTTTTCTGG
AAAGGATGTAATAATTTGTCCGCCTACATTTGAAATGTACGAATTTTATTCCGTCCTCAATGGCTTTTCAGTAAAAAAAA
TCCCTTTGAATACCAATTACGAAATAAAAGACATAGATAAAGCCGTAGATGATCAAACGAGTATGATATTCATCTGTTCG
CCAAACAATCCTACCGGAAACTTGCAACCCCAAAAAGAGATCTTAAAAGCCTTAAAAACAGGAGTCCCTGTAATTGTTGA
CGAAGCATATGCAGATTTCTCAAAAATAAGCATGATACAACATTTAAAAGACTACCCAAATCTTATAATATTAAAAACAT
TTTCCAAAGCGTTCGGATTGGCAGGTATCAGAGCAGGTATCTTAATAGCCAATGAAGAAATAGTTAAACAAATAATGAAA
ATAAAATCCCCTTACAGTTTCAACGTATTAACTGAAAAGATGGTAGAAACCATAATAGAAAATTATAATCTCATTTTAGA
AAAAATTGATTACATCATCGAAGAAAGAAATAAGCTTTCAAAAGAGCTTGGACGAGTTGCCTTAAAAAGTGATGCTAATT
TTATACTCTTGGATTTCGATAAAATAGAAGGTATAACAGCTAAAGCTGTTTACAACTACTTTTTAGAAAATAAAATGCTT
TTGAGAAGATACTCTGGGACTTTAGAAAATAAAATTCGAGTAACCGTTGGAACCAAAGAAGAAAATCAAAAGTTTTTAGC
TCTTTTTAAAGAATTAACTAGTAATTATGATAACAGATCAAGACTTACGAACGTTAAAAAGCAATAA

Upstream 100 bases:

>100_bases
TTTATCATTTGTTGGTGTTATTAACCTACGAAGGAATAGATATAGGAGAAGTTGTTCAAGAATTAAAAAAGAGACACTCG
CCAGAGGGAGGTAAGCAAAG

Downstream 100 bases:

>100_bases
CGATAAGAAGAATATCCTTAAAAATGGAAAAAGGGCGTAAAGCCCTTTTTTACCTTGCCAATTTTAAGATATTTAGAACA
TCTTCCTTGTAAAGTTTTAC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKFNPILESFEEYKPSNTYINDGFIDLSKNENPFDLSLDLKKIFFQKITETNINRYPELTADNIRQKIATFLNSYFSRYN
IDLDMNNIVVGNGSDETISYLVKIFSGKDVIICPPTFEMYEFYSVLNGFSVKKIPLNTNYEIKDIDKAVDDQTSMIFICS
PNNPTGNLQPQKEILKALKTGVPVIVDEAYADFSKISMIQHLKDYPNLIILKTFSKAFGLAGIRAGILIANEEIVKQIMK
IKSPYSFNVLTEKMVETIIENYNLILEKIDYIIEERNKLSKELGRVALKSDANFILLDFDKIEGITAKAVYNYFLENKML
LRRYSGTLENKIRVTVGTKEENQKFLALFKELTSNYDNRSRLTNVKKQ

Sequences:

>Translated_368_residues
MKFNPILESFEEYKPSNTYINDGFIDLSKNENPFDLSLDLKKIFFQKITETNINRYPELTADNIRQKIATFLNSYFSRYN
IDLDMNNIVVGNGSDETISYLVKIFSGKDVIICPPTFEMYEFYSVLNGFSVKKIPLNTNYEIKDIDKAVDDQTSMIFICS
PNNPTGNLQPQKEILKALKTGVPVIVDEAYADFSKISMIQHLKDYPNLIILKTFSKAFGLAGIRAGILIANEEIVKQIMK
IKSPYSFNVLTEKMVETIIENYNLILEKIDYIIEERNKLSKELGRVALKSDANFILLDFDKIEGITAKAVYNYFLENKML
LRRYSGTLENKIRVTVGTKEENQKFLALFKELTSNYDNRSRLTNVKKQ
>Mature_368_residues
MKFNPILESFEEYKPSNTYINDGFIDLSKNENPFDLSLDLKKIFFQKITETNINRYPELTADNIRQKIATFLNSYFSRYN
IDLDMNNIVVGNGSDETISYLVKIFSGKDVIICPPTFEMYEFYSVLNGFSVKKIPLNTNYEIKDIDKAVDDQTSMIFICS
PNNPTGNLQPQKEILKALKTGVPVIVDEAYADFSKISMIQHLKDYPNLIILKTFSKAFGLAGIRAGILIANEEIVKQIMK
IKSPYSFNVLTEKMVETIIENYNLILEKIDYIIEERNKLSKELGRVALKSDANFILLDFDKIEGITAKAVYNYFLENKML
LRRYSGTLENKIRVTVGTKEENQKFLALFKELTSNYDNRSRLTNVKKQ

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=352, Percent_Identity=30.1136363636364, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788722, Length=212, Percent_Identity=24.0566037735849, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=381, Percent_Identity=29.9212598425197, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 42405; Mature: 42405

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNPILESFEEYKPSNTYINDGFIDLSKNENPFDLSLDLKKIFFQKITETNINRYPELT
CCCCHHHHHHHHCCCCCCEECCCEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCC
ADNIRQKIATFLNSYFSRYNIDLDMNNIVVGNGSDETISYLVKIFSGKDVIICPPTFEMY
HHHHHHHHHHHHHHHHHHEECEEECCEEEEECCCCHHHHHHHHHHCCCEEEEECCCHHHH
EFYSVLNGFSVKKIPLNTNYEIKDIDKAVDDQTSMIFICSPNNPTGNLQPQKEILKALKT
HHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHC
GVPVIVDEAYADFSKISMIQHLKDYPNLIILKTFSKAFGLAGIRAGILIANEEIVKQIMK
CCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHCEEEECHHHHHHHHH
IKSPYSFNVLTEKMVETIIENYNLILEKIDYIIEERNKLSKELGRVALKSDANFILLDFD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHH
KIEGITAKAVYNYFLENKMLLRRYSGTLENKIRVTVGTKEENQKFLALFKELTSNYDNRS
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHH
RLTNVKKQ
HHHCCCCC
>Mature Secondary Structure
MKFNPILESFEEYKPSNTYINDGFIDLSKNENPFDLSLDLKKIFFQKITETNINRYPELT
CCCCHHHHHHHHCCCCCCEECCCEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCC
ADNIRQKIATFLNSYFSRYNIDLDMNNIVVGNGSDETISYLVKIFSGKDVIICPPTFEMY
HHHHHHHHHHHHHHHHHHEECEEECCEEEEECCCCHHHHHHHHHHCCCEEEEECCCHHHH
EFYSVLNGFSVKKIPLNTNYEIKDIDKAVDDQTSMIFICSPNNPTGNLQPQKEILKALKT
HHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHC
GVPVIVDEAYADFSKISMIQHLKDYPNLIILKTFSKAFGLAGIRAGILIANEEIVKQIMK
CCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHCEEEECHHHHHHHHH
IKSPYSFNVLTEKMVETIIENYNLILEKIDYIIEERNKLSKELGRVALKSDANFILLDFD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHH
KIEGITAKAVYNYFLENKMLLRRYSGTLENKIRVTVGTKEENQKFLALFKELTSNYDNRS
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHH
RLTNVKKQ
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA