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The map label for this gene is ndk [H]

Identifier: 160902372

GI number: 160902372

Start: 960877

End: 961323

Strand: Direct

Name: ndk [H]

Synonym: Pmob_0907

Alternate gene names: 160902372

Gene position: 960877-961323 (Clockwise)

Preceding gene: 160902371

Following gene: 160902373

Centisome position: 44.29

GC content: 36.02

Gene sequence:

>447_bases
TTGGCGGAAAAAGCATTTGTGATGATAAAACCTAACGCTGTTAAAAGAGGACTAATTGGTGAAATAATCAAAAGATATGA
ACAAAAAGGCCTAAAAGTAGTTGCTATGAAGATGATAAAGATGAAAAAAGCACAAGCTGAAGAGCTCTACAAAGTACACC
AAGGTAAGGATTTTTATCAACCATTGATAGAATTCATACTATCTGGACCTGTGGTTGTTATGATTATAGAAGGCCCAAGG
GTTATTGAAGCTGTTAGAAGTATAAACGGTGAAACGGATCCCCTAAAAGCTCAAGCAGGAAGCATTCGTGGAGAATTTGG
GATAAGTGTCAGAAAGAACATTGTACATGCCTCAGATTCGATTCAAAGTGCTGAACAAGAGTGGAAAATTTTCTTTGAAG
AAAATGAGATTTTTGAATATCTATGCGGGTTTGAAAACGAGTTGTAA

Upstream 100 bases:

>100_bases
CAGTTTTGTATCCATTTTTTTTAGTTATGTCGCATCAAGGCGAGCAGCGAGCTTCAATATTGTCGAATCTTTAAAAGATG
AATAGAAGGGGGAGCTTAAT

Downstream 100 bases:

>100_bases
ACATCAAAGAGGTGAGGTTTATGAGGGTTGTAGGTCTTATTCTTTCTGGATCCACCAAAGATAATTTAGATAAATTAACT
TTAAAAAGAACTAGCGCAGC

Product: nucleoside-diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAEKAFVMIKPNAVKRGLIGEIIKRYEQKGLKVVAMKMIKMKKAQAEELYKVHQGKDFYQPLIEFILSGPVVVMIIEGPR
VIEAVRSINGETDPLKAQAGSIRGEFGISVRKNIVHASDSIQSAEQEWKIFFEENEIFEYLCGFENEL

Sequences:

>Translated_148_residues
MAEKAFVMIKPNAVKRGLIGEIIKRYEQKGLKVVAMKMIKMKKAQAEELYKVHQGKDFYQPLIEFILSGPVVVMIIEGPR
VIEAVRSINGETDPLKAQAGSIRGEFGISVRKNIVHASDSIQSAEQEWKIFFEENEIFEYLCGFENEL
>Mature_147_residues
AEKAFVMIKPNAVKRGLIGEIIKRYEQKGLKVVAMKMIKMKKAQAEELYKVHQGKDFYQPLIEFILSGPVVVMIIEGPRV
IEAVRSINGETDPLKAQAGSIRGEFGISVRKNIVHASDSIQSAEQEWKIFFEENEIFEYLCGFENEL

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI66392227, Length=138, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=9e-32,
Organism=Homo sapiens, GI66392205, Length=138, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=9e-32,
Organism=Homo sapiens, GI4505409, Length=138, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=9e-32,
Organism=Homo sapiens, GI66392192, Length=138, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=9e-32,
Organism=Homo sapiens, GI66392203, Length=138, Percent_Identity=43.4782608695652, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI38045913, Length=145, Percent_Identity=41.3793103448276, Blast_Score=131, Evalue=2e-31,
Organism=Homo sapiens, GI4557797, Length=145, Percent_Identity=41.3793103448276, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI4826862, Length=145, Percent_Identity=37.2413793103448, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI37693993, Length=138, Percent_Identity=39.1304347826087, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI5031951, Length=134, Percent_Identity=33.5820895522388, Blast_Score=83, Evalue=7e-17,
Organism=Homo sapiens, GI37574614, Length=137, Percent_Identity=32.1167883211679, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI7019465, Length=137, Percent_Identity=32.1167883211679, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI148839372, Length=132, Percent_Identity=34.0909090909091, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788866, Length=135, Percent_Identity=41.4814814814815, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17506807, Length=146, Percent_Identity=42.4657534246575, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71995094, Length=133, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322783, Length=139, Percent_Identity=39.568345323741, Blast_Score=130, Evalue=9e-32,
Organism=Drosophila melanogaster, GI45549037, Length=138, Percent_Identity=42.0289855072464, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI18860097, Length=135, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 16820; Mature: 16689

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKAFVMIKPNAVKRGLIGEIIKRYEQKGLKVVAMKMIKMKKAQAEELYKVHQGKDFYQ
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PLIEFILSGPVVVMIIEGPRVIEAVRSINGETDPLKAQAGSIRGEFGISVRKNIVHASDS
HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCHH
IQSAEQEWKIFFEENEIFEYLCGFENEL
HHHHHHHHEEEECHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEKAFVMIKPNAVKRGLIGEIIKRYEQKGLKVVAMKMIKMKKAQAEELYKVHQGKDFYQ
CCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PLIEFILSGPVVVMIIEGPRVIEAVRSINGETDPLKAQAGSIRGEFGISVRKNIVHASDS
HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCHH
IQSAEQEWKIFFEENEIFEYLCGFENEL
HHHHHHHHEEEECHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA