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The map label for this gene is uxaC [H]

Identifier: 160902320

GI number: 160902320

Start: 902032

End: 903399

Strand: Direct

Name: uxaC [H]

Synonym: Pmob_0854

Alternate gene names: 160902320

Gene position: 902032-903399 (Clockwise)

Preceding gene: 160902319

Following gene: 160902321

Centisome position: 41.58

GC content: 35.6

Gene sequence:

>1368_bases
ATGTCTTTTTTGGACGAAAATTATTTACTACAAAACAACACTTCGAAGATGTTGTATAATTCAATTAAAGATTTCCCTAT
CTTAGATGCTCACAATCACGGGGATGTGAAAGAGATCGTTGAGAACAAAGGTTGGGATGACATCTGGCAAGTGGAAGGAG
CCACAGATCATTATGTTTGGGAATCAATGAGAAAAAGAGGGGTACCAGAAGAAAAAATAACCGGAAATGCTTCAAATAAG
GAAAAGTGGATGGCATTGGCTAAAGTTTTCCCTGGGTTCGTTGGCAATCCTACATACGAATGGATACACCTCGATCTAAA
AAGAAGGTTTAAAATAGAAGATACCATTTCAAAGTATACAGCTGAAAAGATATGGCAAGATACTTCTTTATTACTAAAAA
GTGAAAGTATGAAACCTCAACGATTACTAAAAGAAATGAATGTAGAAGTAATGTGTACAACAAATGATCCAACAGAGGAT
CTCTCATTTCATGAAAAAGCTAAAGATATTGAAGGAATAAAGATTCTTCCCACTTGGAGACCAGACAAAGCTATGAACAT
CGAAAAAGAAAATTGGAAAGATTTTGTAGAAAAGTTAGGAGAAATAACAAAAGAAAATGTTGAACGCTTTGAAGGGTTTT
TAAATGCCCTTTACAAGACACACAAAAAATTTGAAAAACTTGGTGGTGTTTCAAGTGACCATGGTATACTTGAACCGATT
TCATACCCAGTTGAAAGAGAGAGAGTAAAAGAAGTCTATGAAAAAGCACTTTCAAAGAAAGAGTTAACGAAACAAGAAAT
TTCAGATTTCAAATCCTTTATGTTTTATGAATTTGGGACGATGAACGCTGAAAGCAATTGGGTTATGCAATTACATATTG
GCGCTATACGAGATTATAGAGACAAGTTATATAATACTTTAGGGCCAGACACCGGAGGGGATATTTCAACCAGCAAAATC
GACTTGGCAAATGGATTAAGATACTTTTTAAACCAATTTGATGAAAAATTGAAAGTTGTTTTGTACTGTTTGGACCCGTC
ACTATTTCCAACCGTTGCCACAATAGCAAGGGCCTTCCCAAACGTTAGCCTTGGAGCGCCTTGGTGGTTCAACGACAGTC
CTTTTGGAATGGAGATATATTTAAAATATATAGCCACCGTTGACCTTCTTAGCGACTTAGCAGGTTGGGTAACAGATTCA
AGAAAGTTAATCTCCTATGGTTCAAGGACAGAGATGTTCAGAAGAGAGTTATCTAACGTTGTTGGTGAAATGGTAGAAAA
AGGTCAAATACCTATCAGGGAAGCATTTGATTTGGTGAGAGATATTAGTTATTTTAGACCAAAAAGGTTGTTTTTTGAAA
AAATTTAG

Upstream 100 bases:

>100_bases
AACATTATAGAAGTTAATAACGTGCTTAAAAGAAAAGGTCCTAAAGCATCTTTTAGAATTTTCAAAGACAGGAAGAATTG
AAGTATAGGAGGTTAGAAAA

Downstream 100 bases:

>100_bases
ATAAAAATTATTGAACTCGGAGGTACCAAGTCGATGAAAAAAGCATCCTTGTCTTCTTTAAAAGAAAACAATGCGGCACT
TATTTTTCAATCATTAAGGA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSFLDENYLLQNNTSKMLYNSIKDFPILDAHNHGDVKEIVENKGWDDIWQVEGATDHYVWESMRKRGVPEEKITGNASNK
EKWMALAKVFPGFVGNPTYEWIHLDLKRRFKIEDTISKYTAEKIWQDTSLLLKSESMKPQRLLKEMNVEVMCTTNDPTED
LSFHEKAKDIEGIKILPTWRPDKAMNIEKENWKDFVEKLGEITKENVERFEGFLNALYKTHKKFEKLGGVSSDHGILEPI
SYPVERERVKEVYEKALSKKELTKQEISDFKSFMFYEFGTMNAESNWVMQLHIGAIRDYRDKLYNTLGPDTGGDISTSKI
DLANGLRYFLNQFDEKLKVVLYCLDPSLFPTVATIARAFPNVSLGAPWWFNDSPFGMEIYLKYIATVDLLSDLAGWVTDS
RKLISYGSRTEMFRRELSNVVGEMVEKGQIPIREAFDLVRDISYFRPKRLFFEKI

Sequences:

>Translated_455_residues
MSFLDENYLLQNNTSKMLYNSIKDFPILDAHNHGDVKEIVENKGWDDIWQVEGATDHYVWESMRKRGVPEEKITGNASNK
EKWMALAKVFPGFVGNPTYEWIHLDLKRRFKIEDTISKYTAEKIWQDTSLLLKSESMKPQRLLKEMNVEVMCTTNDPTED
LSFHEKAKDIEGIKILPTWRPDKAMNIEKENWKDFVEKLGEITKENVERFEGFLNALYKTHKKFEKLGGVSSDHGILEPI
SYPVERERVKEVYEKALSKKELTKQEISDFKSFMFYEFGTMNAESNWVMQLHIGAIRDYRDKLYNTLGPDTGGDISTSKI
DLANGLRYFLNQFDEKLKVVLYCLDPSLFPTVATIARAFPNVSLGAPWWFNDSPFGMEIYLKYIATVDLLSDLAGWVTDS
RKLISYGSRTEMFRRELSNVVGEMVEKGQIPIREAFDLVRDISYFRPKRLFFEKI
>Mature_454_residues
SFLDENYLLQNNTSKMLYNSIKDFPILDAHNHGDVKEIVENKGWDDIWQVEGATDHYVWESMRKRGVPEEKITGNASNKE
KWMALAKVFPGFVGNPTYEWIHLDLKRRFKIEDTISKYTAEKIWQDTSLLLKSESMKPQRLLKEMNVEVMCTTNDPTEDL
SFHEKAKDIEGIKILPTWRPDKAMNIEKENWKDFVEKLGEITKENVERFEGFLNALYKTHKKFEKLGGVSSDHGILEPIS
YPVERERVKEVYEKALSKKELTKQEISDFKSFMFYEFGTMNAESNWVMQLHIGAIRDYRDKLYNTLGPDTGGDISTSKID
LANGLRYFLNQFDEKLKVVLYCLDPSLFPTVATIARAFPNVSLGAPWWFNDSPFGMEIYLKYIATVDLLSDLAGWVTDSR
KLISYGSRTEMFRRELSNVVGEMVEKGQIPIREAFDLVRDISYFRPKRLFFEKI

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=464, Percent_Identity=35.1293103448276, Blast_Score=275, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53021; Mature: 52890

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLDENYLLQNNTSKMLYNSIKDFPILDAHNHGDVKEIVENKGWDDIWQVEGATDHYVW
CCCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHEECCCCCHHHHH
ESMRKRGVPEEKITGNASNKEKWMALAKVFPGFVGNPTYEWIHLDLKRRFKIEDTISKYT
HHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCCHHHHHHHHH
AEKIWQDTSLLLKSESMKPQRLLKEMNVEVMCTTNDPTEDLSFHEKAKDIEGIKILPTWR
HHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCC
PDKAMNIEKENWKDFVEKLGEITKENVERFEGFLNALYKTHKKFEKLGGVSSDHGILEPI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SYPVERERVKEVYEKALSKKELTKQEISDFKSFMFYEFGTMNAESNWVMQLHIGAIRDYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHH
DKLYNTLGPDTGGDISTSKIDLANGLRYFLNQFDEKLKVVLYCLDPSLFPTVATIARAFP
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCC
NVSLGAPWWFNDSPFGMEIYLKYIATVDLLSDLAGWVTDSRKLISYGSRTEMFRRELSNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
VGEMVEKGQIPIREAFDLVRDISYFRPKRLFFEKI
HHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure 
SFLDENYLLQNNTSKMLYNSIKDFPILDAHNHGDVKEIVENKGWDDIWQVEGATDHYVW
CCCCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHEECCCCCHHHHH
ESMRKRGVPEEKITGNASNKEKWMALAKVFPGFVGNPTYEWIHLDLKRRFKIEDTISKYT
HHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCCHHHHHHHHH
AEKIWQDTSLLLKSESMKPQRLLKEMNVEVMCTTNDPTEDLSFHEKAKDIEGIKILPTWR
HHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCC
PDKAMNIEKENWKDFVEKLGEITKENVERFEGFLNALYKTHKKFEKLGGVSSDHGILEPI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SYPVERERVKEVYEKALSKKELTKQEISDFKSFMFYEFGTMNAESNWVMQLHIGAIRDYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHH
DKLYNTLGPDTGGDISTSKIDLANGLRYFLNQFDEKLKVVLYCLDPSLFPTVATIARAFP
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCC
NVSLGAPWWFNDSPFGMEIYLKYIATVDLLSDLAGWVTDSRKLISYGSRTEMFRRELSNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
VGEMVEKGQIPIREAFDLVRDISYFRPKRLFFEKI
HHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]