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The map label for this gene is ypdF [C]

Identifier: 160901881

GI number: 160901881

Start: 425809

End: 426882

Strand: Direct

Name: ypdF [C]

Synonym: Pmob_0397

Alternate gene names: 160901881

Gene position: 425809-426882 (Clockwise)

Preceding gene: 160901880

Following gene: 160901882

Centisome position: 19.63

GC content: 32.96

Gene sequence:

>1074_bases
TTGCGTAAAGATAGAATAGAAAAACTTCTCAATAAGATGGCAAAAAATAATATTTATCAGGCAATAATATCCTCACCACC
TTCTCTTTACTATTTTCTGAATGAGTGGTTTGAACCCGGTGAAAGATTGTTGGTATTATTCGTAAATACTTCTGGCGAAG
TTAAATTGCTAGTCAACGAATTGTTCCCGGTAAATACTGTTGAAGAAGAAAATTTAATCAAATATTCTGATTCAGAAGAT
CCCCTTAAAATTTTATCTTCTCTTATTGAAAAAGATAAACCTATAGGCATAGATGGAAGTTGGGAAACCCGTTTTCTTTT
AGGTTTAATGGATATTATTAAAGATTTATCTTTAAAACAGCTTTCTCCAATAATTAGTGAATTAAGGATGGTAAAAGATG
TTGATGAAATAGCGTTAATGAGGTCTTCTTCTTTATTAAATGACTCAGCTATGGAAAAGGTTATAGACCTAGTATCAGAG
ATGCTTCCAGAAAAATACTTAGCCAAAGCCATCAAAAATATTTTCGAAAGAGAAGGAGCCGATGGAGTTTCTTTTGAACC
TATAGTAGGATACGGTCAGAATACTGCTAATCCTCATCATATGCCTACTAATGCAAAGTTAAAAGATGGAGATGTCGTAT
TACTAGACATGGGTTGCATAAAAAATTATTATTGTTCAGATATGACAAGAACAGTCTTTTTTGGCAAACCTATTGAAACC
TTGAAAAATATTTATCATATAGTTTTAGAAGCCAATTTAAAAGCTATTGAAAAAATAAAACCTGGCCTTAAGGCGTCTGA
AATTGATGCTACCTCGCGTAATTATATAGAAAGCAAAGGATATGGAAAGTACTTTACTCATCGAACAGGGCATGGTGTAG
GGATAGAGATTCATGAAAAACCTTACATATCTTCAAATAGCGAAGAAATTCTAACACCTGGCATGATCTTTTCAATAGAA
CCGGGAATCTATTTACCTGGTGTCGGCGGAGTAAGAATAGAAGATCTGGTTTTGGTGACTGATAATGGTTGTGAAGTATT
AAATAGGTATCCAAAAGATTTCTTGGTAATTTAA

Upstream 100 bases:

>100_bases
AAGTAGATAAGATATTATCTACTTCCTACTTTTTTATGATACAATTATGAATATAAAATCGAATGAAATTAGACACTATT
CATGGGAGGCGCTTTGAAGG

Downstream 100 bases:

>100_bases
TCACTTCTTATGCTTTCGATCAATTCTTTGCTACTAATTGAAACTAGAGTCTTTTTTCACTAATTTAGTTAGTACCCTCC
GCTTCGCTGAACTCATTTTG

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRKDRIEKLLNKMAKNNIYQAIISSPPSLYYFLNEWFEPGERLLVLFVNTSGEVKLLVNELFPVNTVEEENLIKYSDSED
PLKILSSLIEKDKPIGIDGSWETRFLLGLMDIIKDLSLKQLSPIISELRMVKDVDEIALMRSSSLLNDSAMEKVIDLVSE
MLPEKYLAKAIKNIFEREGADGVSFEPIVGYGQNTANPHHMPTNAKLKDGDVVLLDMGCIKNYYCSDMTRTVFFGKPIET
LKNIYHIVLEANLKAIEKIKPGLKASEIDATSRNYIESKGYGKYFTHRTGHGVGIEIHEKPYISSNSEEILTPGMIFSIE
PGIYLPGVGGVRIEDLVLVTDNGCEVLNRYPKDFLVI

Sequences:

>Translated_357_residues
MRKDRIEKLLNKMAKNNIYQAIISSPPSLYYFLNEWFEPGERLLVLFVNTSGEVKLLVNELFPVNTVEEENLIKYSDSED
PLKILSSLIEKDKPIGIDGSWETRFLLGLMDIIKDLSLKQLSPIISELRMVKDVDEIALMRSSSLLNDSAMEKVIDLVSE
MLPEKYLAKAIKNIFEREGADGVSFEPIVGYGQNTANPHHMPTNAKLKDGDVVLLDMGCIKNYYCSDMTRTVFFGKPIET
LKNIYHIVLEANLKAIEKIKPGLKASEIDATSRNYIESKGYGKYFTHRTGHGVGIEIHEKPYISSNSEEILTPGMIFSIE
PGIYLPGVGGVRIEDLVLVTDNGCEVLNRYPKDFLVI
>Mature_357_residues
MRKDRIEKLLNKMAKNNIYQAIISSPPSLYYFLNEWFEPGERLLVLFVNTSGEVKLLVNELFPVNTVEEENLIKYSDSED
PLKILSSLIEKDKPIGIDGSWETRFLLGLMDIIKDLSLKQLSPIISELRMVKDVDEIALMRSSSLLNDSAMEKVIDLVSE
MLPEKYLAKAIKNIFEREGADGVSFEPIVGYGQNTANPHHMPTNAKLKDGDVVLLDMGCIKNYYCSDMTRTVFFGKPIET
LKNIYHIVLEANLKAIEKIKPGLKASEIDATSRNYIESKGYGKYFTHRTGHGVGIEIHEKPYISSNSEEILTPGMIFSIE
PGIYLPGVGGVRIEDLVLVTDNGCEVLNRYPKDFLVI

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=254, Percent_Identity=29.1338582677165, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI93141226, Length=266, Percent_Identity=29.6992481203008, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI264681563, Length=226, Percent_Identity=31.858407079646, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI149589008, Length=297, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI260593665, Length=297, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI264681565, Length=223, Percent_Identity=29.5964125560538, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI164420681, Length=172, Percent_Identity=25, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788728, Length=275, Percent_Identity=38.5454545454545, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789275, Length=255, Percent_Identity=28.2352941176471, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786364, Length=185, Percent_Identity=31.3513513513514, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508215, Length=292, Percent_Identity=26.3698630136986, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=233, Percent_Identity=29.1845493562232, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=262, Percent_Identity=24.8091603053435, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321118, Length=286, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322999, Length=172, Percent_Identity=33.7209302325581, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19920384, Length=262, Percent_Identity=27.8625954198473, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161078230, Length=239, Percent_Identity=30.1255230125523, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357287, Length=239, Percent_Identity=30.1255230125523, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357079, Length=299, Percent_Identity=25.4180602006689, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355531, Length=172, Percent_Identity=26.1627906976744, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137632, Length=166, Percent_Identity=30.7228915662651, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40258; Mature: 40258

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00491 PROLINE_PEPTIDASE ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDRIEKLLNKMAKNNIYQAIISSPPSLYYFLNEWFEPGERLLVLFVNTSGEVKLLVNE
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEC
LFPVNTVEEENLIKYSDSEDPLKILSSLIEKDKPIGIDGSWETRFLLGLMDIIKDLSLKQ
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
LSPIISELRMVKDVDEIALMRSSSLLNDSAMEKVIDLVSEMLPEKYLAKAIKNIFEREGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DGVSFEPIVGYGQNTANPHHMPTNAKLKDGDVVLLDMGCIKNYYCSDMTRTVFFGKPIET
CCCCCCCEECCCCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHCCCHHHEEECCHHHH
LKNIYHIVLEANLKAIEKIKPGLKASEIDATSRNYIESKGYGKYFTHRTGHGVGIEIHEK
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHCCCCCCHHCCCCCCCCEEEEECC
PYISSNSEEILTPGMIFSIEPGIYLPGVGGVRIEDLVLVTDNGCEVLNRYPKDFLVI
CCCCCCCCCEECCCEEEEECCCEEECCCCCCEEEEEEEEECCCHHHHHCCCCCEECC
>Mature Secondary Structure
MRKDRIEKLLNKMAKNNIYQAIISSPPSLYYFLNEWFEPGERLLVLFVNTSGEVKLLVNE
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEC
LFPVNTVEEENLIKYSDSEDPLKILSSLIEKDKPIGIDGSWETRFLLGLMDIIKDLSLKQ
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
LSPIISELRMVKDVDEIALMRSSSLLNDSAMEKVIDLVSEMLPEKYLAKAIKNIFEREGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DGVSFEPIVGYGQNTANPHHMPTNAKLKDGDVVLLDMGCIKNYYCSDMTRTVFFGKPIET
CCCCCCCEECCCCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHCCCHHHEEECCHHHH
LKNIYHIVLEANLKAIEKIKPGLKASEIDATSRNYIESKGYGKYFTHRTGHGVGIEIHEK
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHCCCCCCHHCCCCCCCCEEEEECC
PYISSNSEEILTPGMIFSIEPGIYLPGVGGVRIEDLVLVTDNGCEVLNRYPKDFLVI
CCCCCCCCCEECCCEEEEECCCEEECCCCCCEEEEEEEEECCCHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]