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The map label for this gene is ahpC [C]

Identifier: 160901880

GI number: 160901880

Start: 425037

End: 425687

Strand: Direct

Name: ahpC [C]

Synonym: Pmob_0396

Alternate gene names: 160901880

Gene position: 425037-425687 (Clockwise)

Preceding gene: 160901872

Following gene: 160901881

Centisome position: 19.59

GC content: 38.4

Gene sequence:

>651_bases
ATGGAAGGAAGGATTCCTTTAATTGGAGAAAAGTTTCCTGAAATGAAAGTATTAACAACGGACGGTGCAAAAGAACTACC
AAAAGACTACAAAGGAAAATGGTTGGTGCTCTTCAGCCATCCAGGAGATTTTACACCTGTTTGTACAACAGAATTTGTTG
AATTTGCAAAAAAGCATGAAGATTTCAAAAAGATCAACACGGAACTTTTAGGACTTTCTGTTGATGCCGTTCATTCACAT
ATCAAATGGATGGAATGGATCAAAGATAACCTTGGAGTAGAAATTACTTTCCCTATAATAGCTGATACAATGGGAAGAGT
AGCCTCAAGATTGGGAATGGTAGACCCCGAAAAAGGTTCCGCAACTGTTAGAGCAGTTTTCATCTTAGATCCTGAAGGAA
CCATTAGATTGATCATGTACTATCCTTCTGAGGTTGGAAGATACATCGAGGAAATATACCGAGCTGTAAGAGCTTTACAA
TTGGCAGACAAAAACAAGGTAGTAACCCCAGCCAATTGGCCCGAAAACTCGATATTTGGAAGTAAAGTAATAATTCCACC
AGCATCAACTTATGCTGAAGCAATGAAGAGAAAAACGTCAGCCGAAGAAGGATACGATTGGTGGCTAAAGGTTAAAGAAG
TTAAAGAATAA

Upstream 100 bases:

>100_bases
TACTTGACTTTTCTATTTTTTAGGTATATAATTTTTTTAGACAAACCTAAAAAATAGATATTTCATAAATAAAAAATCAT
CAAATAGGAGGTAGGTAAAT

Downstream 100 bases:

>100_bases
TACTAAACCCCAGCTAGTAGGAAGTAGATAAGATATTATCTACTTCCTACTTTTTTATGATACAATTATGAATATAAAAT
CGAATGAAATTAGACACTAT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MEGRIPLIGEKFPEMKVLTTDGAKELPKDYKGKWLVLFSHPGDFTPVCTTEFVEFAKKHEDFKKINTELLGLSVDAVHSH
IKWMEWIKDNLGVEITFPIIADTMGRVASRLGMVDPEKGSATVRAVFILDPEGTIRLIMYYPSEVGRYIEEIYRAVRALQ
LADKNKVVTPANWPENSIFGSKVIIPPASTYAEAMKRKTSAEEGYDWWLKVKEVKE

Sequences:

>Translated_216_residues
MEGRIPLIGEKFPEMKVLTTDGAKELPKDYKGKWLVLFSHPGDFTPVCTTEFVEFAKKHEDFKKINTELLGLSVDAVHSH
IKWMEWIKDNLGVEITFPIIADTMGRVASRLGMVDPEKGSATVRAVFILDPEGTIRLIMYYPSEVGRYIEEIYRAVRALQ
LADKNKVVTPANWPENSIFGSKVIIPPASTYAEAMKRKTSAEEGYDWWLKVKEVKE
>Mature_216_residues
MEGRIPLIGEKFPEMKVLTTDGAKELPKDYKGKWLVLFSHPGDFTPVCTTEFVEFAKKHEDFKKINTELLGLSVDAVHSH
IKWMEWIKDNLGVEITFPIIADTMGRVASRLGMVDPEKGSATVRAVFILDPEGTIRLIMYYPSEVGRYIEEIYRAVRALQ
LADKNKVVTPANWPENSIFGSKVIIPPASTYAEAMKRKTSAEEGYDWWLKVKEVKE

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=38.6934673366834, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32189392, Length=174, Percent_Identity=38.5057471264368, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI5453549, Length=159, Percent_Identity=37.7358490566038, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI4505591, Length=150, Percent_Identity=37.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI32455266, Length=150, Percent_Identity=37.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI32455264, Length=150, Percent_Identity=37.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI5802974, Length=150, Percent_Identity=37.3333333333333, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI32483377, Length=150, Percent_Identity=37.3333333333333, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=48.1481481481481, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786822, Length=149, Percent_Identity=30.8724832214765, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=36.4583333333333, Blast_Score=126, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=151, Percent_Identity=36.4238410596026, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32565831, Length=170, Percent_Identity=38.2352941176471, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193204376, Length=170, Percent_Identity=38.2352941176471, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319407, Length=175, Percent_Identity=51.4285714285714, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6323613, Length=145, Percent_Identity=37.2413793103448, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320661, Length=145, Percent_Identity=34.4827586206897, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652436, Length=199, Percent_Identity=43.21608040201, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17975518, Length=199, Percent_Identity=43.21608040201, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24652434, Length=199, Percent_Identity=43.21608040201, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24581278, Length=194, Percent_Identity=37.1134020618557, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17738015, Length=151, Percent_Identity=38.4105960264901, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17157991, Length=146, Percent_Identity=41.0958904109589, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641739, Length=146, Percent_Identity=41.0958904109589, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=36.3013698630137, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24656348, Length=158, Percent_Identity=34.8101265822785, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17864676, Length=158, Percent_Identity=34.8101265822785, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24551; Mature: 24551

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRIPLIGEKFPEMKVLTTDGAKELPKDYKGKWLVLFSHPGDFTPVCTTEFVEFAKKHE
CCCCCCCCCCCCCCEEEEECCCHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
DFKKINTELLGLSVDAVHSHIKWMEWIKDNLGVEITFPIIADTMGRVASRLGMVDPEKGS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCC
ATVRAVFILDPEGTIRLIMYYPSEVGRYIEEIYRAVRALQLADKNKVVTPANWPENSIFG
EEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
SKVIIPPASTYAEAMKRKTSAEEGYDWWLKVKEVKE
CEEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MEGRIPLIGEKFPEMKVLTTDGAKELPKDYKGKWLVLFSHPGDFTPVCTTEFVEFAKKHE
CCCCCCCCCCCCCCEEEEECCCHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
DFKKINTELLGLSVDAVHSHIKWMEWIKDNLGVEITFPIIADTMGRVASRLGMVDPEKGS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCC
ATVRAVFILDPEGTIRLIMYYPSEVGRYIEEIYRAVRALQLADKNKVVTPANWPENSIFG
EEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
SKVIIPPASTYAEAMKRKTSAEEGYDWWLKVKEVKE
CEEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]