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The map label for this gene is hutU [H]

Identifier: 160901726

GI number: 160901726

Start: 254032

End: 256059

Strand: Direct

Name: hutU [H]

Synonym: Pmob_0240

Alternate gene names: 160901726

Gene position: 254032-256059 (Clockwise)

Preceding gene: 160901725

Following gene: 160901727

Centisome position: 11.71

GC content: 40.14

Gene sequence:

>2028_bases
ATGGTGAACAATATTGATATTTCAAATGCAATGTCCATTAAGTTGGATGATGAACTCCCTCCTATGCCCAAATTCATCGA
AGGCATAAGAAGGGCACCTAAAAGACCTTTAAACTTATCAAAAAGAGAAGTAGAACTAGCCCTTGCAAACGCCTTAAGGT
ACGTGCCGGAAAATTTGCATGAAAAATTGGCTCCAGAATTTCTGCAAGAGTTGCTTACTCGAGGTAGAATTTATGGATAC
AGGTATAGGCCTGAGGGCAACATTAAGGCAAAACCTATAGATATGTACAAGGGTAAATGTACTGAAGGAAAGGCATTTCA
GGTCATGATCGACAACAACTTGGATTTCGATGTTGCTTTGTATCCTTATGAACTGGTAACCTACGGTGAAACCGGTCAAG
TATGTCAAAATTGGATGCAGTACAGATTGATTAAAAAGTACCTAGAAGAACTAACAAGGGAACAAACTTTAGTTGTGGCT
TCAGGACATCCCCTTGGCTTGTTCAGATCAACACCAAATAGTCCACGAGTGATAATAACAAACGCTTTGATGGTTGGGAT
GTTTGATGACCAAGAACATTGGATCAAGGCACAAGCTATGGGTGTTGCCAACTACGGGCAAATGACTGCGGGAGGTTGGA
TGTATATAGGACCTCAAGGTATCGTTCATGGCACTTACAATACCTTGTTGAACGCTGGAAGGTTGAAATTAGGGATACCA
CAAGATAGTGATCTAAGAGGACGTTTATTTGTTAGTTCAGGTTTAGGTGGAATGAGCGGTGCTCAAGCTAAAGCGATAGA
AATCGCAAGAGGCGTTGGAATAATTGCAGAAGTGGATTATTCGAGAATACAAACAAGACTAAACCAAGGTTGGTTAAAAA
CCTACAGCAAAGATTTGGACGAAGTTTTTGAAATAGCCTTCGATCATCTGAATAGAAAAGAACCCATTTCCATCGGTTAT
TATGGTAATATTGTAGATCTATTGGAATACATTGTAAAGAAAGGTATAAAGGTAGATTTGCTATCAGATCAGACGTCTTG
TCACGCTGCCTACGAGGGAGGGTACTGCCCGCAAGGCTTGACTCATGAAGAGAAGAATCACCTCTTAGAAACAAATAAAG
AGAGATTTGTTGAATTAGTCAACAATTCATTGAGAAGACATTTCGAGCTTATAAAAACAATGGTTGAAAGGGGAACCTAC
TTTTTTGACTATGGGAATAGTTTCATGAAGGCGATTTTTGATGCAGGAGTGAAAGAAATAGCAAAAAATGGGTTGGATGA
AAGCGAAGGGTTCATATTTCCCTCGTATGTGGAAGATATAATGGGGCCATTAATATTCGACTATGGTTATGGACCTTTCA
GGTGGGTATGTTTAAGTGGAAAACGGGAAGATCTATTGAAAACGGATAAAGCAGCGATGGAATGCATAGATCCCAACAGA
AGGGGTCAGGATAGAGATAACTACATATGGATTAGAGATGCAGATAAAAACAATCTTGTTGTTGGTACTCAAGCACGAAT
TCTTTATCAGGATGCTATGGGCAGGATGAAGATAGCCCTTAAATTCAACGAAATGGTTAGAAAAGGGGAAGTTGGCCCCA
TTATGCTTGGAAGGGATCATCACGATGCAGGCGGAGCTGACTCTCCTTTTAGAGAAACAGCGAATATAAAAGATGGGAGT
AATATAATGGCGGATATGGCAACCCATGATTTCGCTGGAAATATAGCAAGGGGAATGAGTTTGGTAACACTGCACAACGG
AGGTGGAGTTGGTATCGGTAAGGCCATTAACGGTGGCTTTGGCTTGGTTCTGGATGGAAGTGAAAGGGTGGATGAAATAA
TAAAGAACGCAATTCCATGGGATGTTATGGTTGGTGTCGCCAGGCGATCATGGGCTAGGAATGAAGCTTCTATAGAAACA
TCCATAGAGTACAACAAAGAAAACAAAAATACAGACCACATAACTTTACCGTACATTGCTGATGAAAATATGGTAAAAGA
TTTAGTTGATAAATATTATCAGGGTTAG

Upstream 100 bases:

>100_bases
AAATGATAGATAAGAGTGAAGAAATCTTAAAATCTGGCATAATCGTTAAAGAAGTGGAAAAAGAAACTGGTAAATTATTT
TAAAGAAAGGAGAAATTATC

Downstream 100 bases:

>100_bases
GAGGTAGATACTTTGAACAAAATTGTAGAATGTGTTCCAAATTTCAGTGAAGGAAGAGATAAAGAAAAATTAGAGCGTAT
TGTAGATGAAATAAGAAAAC

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MVNNIDISNAMSIKLDDELPPMPKFIEGIRRAPKRPLNLSKREVELALANALRYVPENLHEKLAPEFLQELLTRGRIYGY
RYRPEGNIKAKPIDMYKGKCTEGKAFQVMIDNNLDFDVALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTREQTLVVA
SGHPLGLFRSTPNSPRVIITNALMVGMFDDQEHWIKAQAMGVANYGQMTAGGWMYIGPQGIVHGTYNTLLNAGRLKLGIP
QDSDLRGRLFVSSGLGGMSGAQAKAIEIARGVGIIAEVDYSRIQTRLNQGWLKTYSKDLDEVFEIAFDHLNRKEPISIGY
YGNIVDLLEYIVKKGIKVDLLSDQTSCHAAYEGGYCPQGLTHEEKNHLLETNKERFVELVNNSLRRHFELIKTMVERGTY
FFDYGNSFMKAIFDAGVKEIAKNGLDESEGFIFPSYVEDIMGPLIFDYGYGPFRWVCLSGKREDLLKTDKAAMECIDPNR
RGQDRDNYIWIRDADKNNLVVGTQARILYQDAMGRMKIALKFNEMVRKGEVGPIMLGRDHHDAGGADSPFRETANIKDGS
NIMADMATHDFAGNIARGMSLVTLHNGGGVGIGKAINGGFGLVLDGSERVDEIIKNAIPWDVMVGVARRSWARNEASIET
SIEYNKENKNTDHITLPYIADENMVKDLVDKYYQG

Sequences:

>Translated_675_residues
MVNNIDISNAMSIKLDDELPPMPKFIEGIRRAPKRPLNLSKREVELALANALRYVPENLHEKLAPEFLQELLTRGRIYGY
RYRPEGNIKAKPIDMYKGKCTEGKAFQVMIDNNLDFDVALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTREQTLVVA
SGHPLGLFRSTPNSPRVIITNALMVGMFDDQEHWIKAQAMGVANYGQMTAGGWMYIGPQGIVHGTYNTLLNAGRLKLGIP
QDSDLRGRLFVSSGLGGMSGAQAKAIEIARGVGIIAEVDYSRIQTRLNQGWLKTYSKDLDEVFEIAFDHLNRKEPISIGY
YGNIVDLLEYIVKKGIKVDLLSDQTSCHAAYEGGYCPQGLTHEEKNHLLETNKERFVELVNNSLRRHFELIKTMVERGTY
FFDYGNSFMKAIFDAGVKEIAKNGLDESEGFIFPSYVEDIMGPLIFDYGYGPFRWVCLSGKREDLLKTDKAAMECIDPNR
RGQDRDNYIWIRDADKNNLVVGTQARILYQDAMGRMKIALKFNEMVRKGEVGPIMLGRDHHDAGGADSPFRETANIKDGS
NIMADMATHDFAGNIARGMSLVTLHNGGGVGIGKAINGGFGLVLDGSERVDEIIKNAIPWDVMVGVARRSWARNEASIET
SIEYNKENKNTDHITLPYIADENMVKDLVDKYYQG
>Mature_675_residues
MVNNIDISNAMSIKLDDELPPMPKFIEGIRRAPKRPLNLSKREVELALANALRYVPENLHEKLAPEFLQELLTRGRIYGY
RYRPEGNIKAKPIDMYKGKCTEGKAFQVMIDNNLDFDVALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTREQTLVVA
SGHPLGLFRSTPNSPRVIITNALMVGMFDDQEHWIKAQAMGVANYGQMTAGGWMYIGPQGIVHGTYNTLLNAGRLKLGIP
QDSDLRGRLFVSSGLGGMSGAQAKAIEIARGVGIIAEVDYSRIQTRLNQGWLKTYSKDLDEVFEIAFDHLNRKEPISIGY
YGNIVDLLEYIVKKGIKVDLLSDQTSCHAAYEGGYCPQGLTHEEKNHLLETNKERFVELVNNSLRRHFELIKTMVERGTY
FFDYGNSFMKAIFDAGVKEIAKNGLDESEGFIFPSYVEDIMGPLIFDYGYGPFRWVCLSGKREDLLKTDKAAMECIDPNR
RGQDRDNYIWIRDADKNNLVVGTQARILYQDAMGRMKIALKFNEMVRKGEVGPIMLGRDHHDAGGADSPFRETANIKDGS
NIMADMATHDFAGNIARGMSLVTLHNGGGVGIGKAINGGFGLVLDGSERVDEIIKNAIPWDVMVGVARRSWARNEASIET
SIEYNKENKNTDHITLPYIADENMVKDLVDKYYQG

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=655, Percent_Identity=46.8702290076336, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI260306182, Length=372, Percent_Identity=44.3548387096774, Blast_Score=304, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI71997891, Length=658, Percent_Identity=48.0243161094225, Blast_Score=600, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 75990; Mature: 75990

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNNIDISNAMSIKLDDELPPMPKFIEGIRRAPKRPLNLSKREVELALANALRYVPENLH
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EKLAPEFLQELLTRGRIYGYRYRPEGNIKAKPIDMYKGKCTEGKAFQVMIDNNLDFDVAL
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
YPYELVTYGETGQVCQNWMQYRLIKKYLEELTREQTLVVASGHPLGLFRSTPNSPRVIIT
ECEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCEEEEE
NALMVGMFDDQEHWIKAQAMGVANYGQMTAGGWMYIGPQGIVHGTYNTLLNAGRLKLGIP
EEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECCHHHHHCCCCEEECCC
QDSDLRGRLFVSSGLGGMSGAQAKAIEIARGVGIIAEVDYSRIQTRLNQGWLKTYSKDLD
CCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
EVFEIAFDHLNRKEPISIGYYGNIVDLLEYIVKKGIKVDLLSDQTSCHAAYEGGYCPQGL
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHEEECCCCCCCCC
THEEKNHLLETNKERFVELVNNSLRRHFELIKTMVERGTYFFDYGNSFMKAIFDAGVKEI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
AKNGLDESEGFIFPSYVEDIMGPLIFDYGYGPFRWVCLSGKREDLLKTDKAAMECIDPNR
HHCCCCCCCCEECHHHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
RGQDRDNYIWIRDADKNNLVVGTQARILYQDAMGRMKIALKFNEMVRKGEVGPIMLGRDH
CCCCCCCEEEEEECCCCCEEEECCHHHHHHHCCCCEEEEEEHHHHHHCCCCCCEEECCCC
HDAGGADSPFRETANIKDGSNIMADMATHDFAGNIARGMSLVTLHNGGGVGIGKAINGGF
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCHHHCCEEEEEEECCCCEEECCCCCCCE
GLVLDGSERVDEIIKNAIPWDVMVGVARRSWARNEASIETSIEYNKENKNTDHITLPYIA
EEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEC
DENMVKDLVDKYYQG
CHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNNIDISNAMSIKLDDELPPMPKFIEGIRRAPKRPLNLSKREVELALANALRYVPENLH
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EKLAPEFLQELLTRGRIYGYRYRPEGNIKAKPIDMYKGKCTEGKAFQVMIDNNLDFDVAL
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
YPYELVTYGETGQVCQNWMQYRLIKKYLEELTREQTLVVASGHPLGLFRSTPNSPRVIIT
ECEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCEEEEE
NALMVGMFDDQEHWIKAQAMGVANYGQMTAGGWMYIGPQGIVHGTYNTLLNAGRLKLGIP
EEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEECCHHHHHCCCCEEECCC
QDSDLRGRLFVSSGLGGMSGAQAKAIEIARGVGIIAEVDYSRIQTRLNQGWLKTYSKDLD
CCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
EVFEIAFDHLNRKEPISIGYYGNIVDLLEYIVKKGIKVDLLSDQTSCHAAYEGGYCPQGL
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHEEECCCCCCCCC
THEEKNHLLETNKERFVELVNNSLRRHFELIKTMVERGTYFFDYGNSFMKAIFDAGVKEI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
AKNGLDESEGFIFPSYVEDIMGPLIFDYGYGPFRWVCLSGKREDLLKTDKAAMECIDPNR
HHCCCCCCCCEECHHHHHHHHHHHEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC
RGQDRDNYIWIRDADKNNLVVGTQARILYQDAMGRMKIALKFNEMVRKGEVGPIMLGRDH
CCCCCCCEEEEEECCCCCEEEECCHHHHHHHCCCCEEEEEEHHHHHHCCCCCCEEECCCC
HDAGGADSPFRETANIKDGSNIMADMATHDFAGNIARGMSLVTLHNGGGVGIGKAINGGF
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHCHHHCCEEEEEEECCCCEEECCCCCCCE
GLVLDGSERVDEIIKNAIPWDVMVGVARRSWARNEASIETSIEYNKENKNTDHITLPYIA
EEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEC
DENMVKDLVDKYYQG
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA