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The map label for this gene is nrdR

Identifier: 160901646

GI number: 160901646

Start: 158769

End: 159221

Strand: Direct

Name: nrdR

Synonym: Pmob_0157

Alternate gene names: 160901646

Gene position: 158769-159221 (Clockwise)

Preceding gene: 160901645

Following gene: 160901647

Centisome position: 7.32

GC content: 33.77

Gene sequence:

>453_bases
ATGAAATGTCCTTTCTGTGGTTACGAGGAAACTAAAGTTCTGGACTCAAGACCAGTTAGTAACGGCACTTCCATAAGAAG
AAGAAGAGAGTGCTTGCAATGCCAAGCGCGCTTTACAACTTATGAAAGATACGAGCAAACAAGGATAAGAATAATAAAAA
AAGATGGCAGAAGAGAACTTTACGATAGAAAAAAACTAATGAACGGGATCTTAAAAGCTTGTGAAAAAAGGCCTGTAAGT
ACTGATCAAATCGAAGAAATTGTTGATAATATAGAAGAACAATTAAGAAGAAGTGGCAATTCAGAAATTTATTCTTCTGA
AATTGGTGATAAGGTTATGGAGCAATTGAAATCAATCGACCAGGTAGCTTATGTGAGATTTGCTTCCGTGTATAAAGAAT
TTAGAGATTTAGACAGCTTTTTACAAGCTATAAGAGAATTAAAAAATAGTTAA

Upstream 100 bases:

>100_bases
AATGAAAAAATCTACCTTGTACAACAAACTAAAAAAAATCTCAAAAATTGCCGAATCTCTAAAAAATACCTAATTTAGGT
AAAATGGTGGTGCAATAATT

Downstream 100 bases:

>100_bases
TCACCATTATTAGAAATGGGAGGAGCGATACAAAAGTGGCTGAACAAGTATACCAACTAACCCGAGAAGGGTACGAAAAA
TTAAAGAGGGAACGAGAAGA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRRELYDRKKLMNGILKACEKRPVS
TDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSIDQVAYVRFASVYKEFRDLDSFLQAIRELKNS

Sequences:

>Translated_150_residues
MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRRELYDRKKLMNGILKACEKRPVS
TDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSIDQVAYVRFASVYKEFRDLDSFLQAIRELKNS
>Mature_150_residues
MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRRELYDRKKLMNGILKACEKRPVS
TDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSIDQVAYVRFASVYKEFRDLDSFLQAIRELKNS

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=49.6644295302013, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PETMO (A9BFB9)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001567227.1
- GeneID:   5757287
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_0157
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   PMOB403833:PMOB_0157-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17776; Mature: 17776

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRREL
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YDRKKLMNGILKACEKRPVSTDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QVAYVRFASVYKEFRDLDSFLQAIRELKNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCGYEETKVLDSRPVSNGTSIRRRRECLQCQARFTTYERYEQTRIRIIKKDGRREL
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YDRKKLMNGILKACEKRPVSTDQIEEIVDNIEEQLRRSGNSEIYSSEIGDKVMEQLKSID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QVAYVRFASVYKEFRDLDSFLQAIRELKNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA