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The map label for this gene is arlR [H]

Identifier: 160901586

GI number: 160901586

Start: 93291

End: 93965

Strand: Direct

Name: arlR [H]

Synonym: Pmob_0095

Alternate gene names: 160901586

Gene position: 93291-93965 (Clockwise)

Preceding gene: 160901585

Following gene: 160901587

Centisome position: 4.3

GC content: 30.81

Gene sequence:

>675_bases
ATGTTTAGAATTCTAGTGGTAGAAGATGATAAAGCAATCTCAAGGCTTTTAGAGTTGGAATTAACTCATGTCGGCTACAA
CGTAAAAATAGCAAAAGATGGAGATGAGGCTTTAAAATTCTATGAAAATTTTAAGCCTGATATAATATTATTGGATATAA
TGTTGCCTATAAGAGATGGATTTGAAGTTGCTGAGGCAATTAGAGACTATGACAGTGATATTGGAATAATAATGATCACA
GCCAAAGGAGAGTTGGAAAGTAAGGTTAAAGGTTTAAAAAATGCTGATGATTATGTCGTTAAACCTTTTGAAATAGAAGA
AATATTGGCAAGAATAGAGGCTTTATTAAAAAGAATGGGGAAAACTAAAGAACTAATAAAAGTAGGAGACATAGAGATTT
ATCCTCAAAACATGGAAGTTCTTGTAAACAAAAAAAATGTTCATTTGAGCCTCACGGAATTTAACATACTAAAGTTACTG
GCTATCAATAAAAATATAGTTGTCTCAAAAGAAAAAATCTTAGAAGAGATTTGGGGATACTACGATGAAGAGAACAACAA
CTTAGTTGAAGTATACATCAATTATTTAAGAAAAAAATTGAAAGATTCCACACAAAATATAGAAACTGTGCGAGGTGTTG
GTTACGTTATTAGGGAGAAAGAAAGTAAAACATAG

Upstream 100 bases:

>100_bases
CATCAAAGCTTACACACTATCAGTTTATCAATTGAATTTTAACTAGGGGCGCTATTAAAGTTTTTAAAGACATTAATTTT
AATTTTGGGGAGGATTACAA

Downstream 100 bases:

>100_bases
TGCAATTTTTAGACAAACAATAGTTTTTACAGCCATTACTATGAGTATAGTATTGACAATTGTTGGCATAGTGAGGATCG
TTTTTGTACAATTCACACTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MFRILVVEDDKAISRLLELELTHVGYNVKIAKDGDEALKFYENFKPDIILLDIMLPIRDGFEVAEAIRDYDSDIGIIMIT
AKGELESKVKGLKNADDYVVKPFEIEEILARIEALLKRMGKTKELIKVGDIEIYPQNMEVLVNKKNVHLSLTEFNILKLL
AINKNIVVSKEKILEEIWGYYDEENNNLVEVYINYLRKKLKDSTQNIETVRGVGYVIREKESKT

Sequences:

>Translated_224_residues
MFRILVVEDDKAISRLLELELTHVGYNVKIAKDGDEALKFYENFKPDIILLDIMLPIRDGFEVAEAIRDYDSDIGIIMIT
AKGELESKVKGLKNADDYVVKPFEIEEILARIEALLKRMGKTKELIKVGDIEIYPQNMEVLVNKKNVHLSLTEFNILKLL
AINKNIVVSKEKILEEIWGYYDEENNNLVEVYINYLRKKLKDSTQNIETVRGVGYVIREKESKT
>Mature_224_residues
MFRILVVEDDKAISRLLELELTHVGYNVKIAKDGDEALKFYENFKPDIILLDIMLPIRDGFEVAEAIRDYDSDIGIIMIT
AKGELESKVKGLKNADDYVVKPFEIEEILARIEALLKRMGKTKELIKVGDIEIYPQNMEVLVNKKNVHLSLTEFNILKLL
AINKNIVVSKEKILEEIWGYYDEENNNLVEVYINYLRKKLKDSTQNIETVRGVGYVIREKESKT

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.0909090909091, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=31.6742081447964, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=35.2941176470588, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=31.2217194570136, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=31.9634703196347, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=32.1266968325792, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.981981981982, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=30.2127659574468, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=33.4782608695652, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=28.8288288288288, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=32.2869955156951, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=29.3333333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=26.7543859649123, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=26.6094420600858, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25896; Mature: 25896

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRILVVEDDKAISRLLELELTHVGYNVKIAKDGDEALKFYENFKPDIILLDIMLPIRDG
CEEEEEEECCHHHHHHHHHHHEECCEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCCCC
FEVAEAIRDYDSDIGIIMITAKGELESKVKGLKNADDYVVKPFEIEEILARIEALLKRMG
HHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
KTKELIKVGDIEIYPQNMEVLVNKKNVHLSLTEFNILKLLAINKNIVVSKEKILEEIWGY
CHHHHEEECCEEECCCCEEEEEECCCEEEEEEHHHEEEEEEECCCEEECHHHHHHHHCCC
YDEENNNLVEVYINYLRKKLKDSTQNIETVRGVGYVIREKESKT
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MFRILVVEDDKAISRLLELELTHVGYNVKIAKDGDEALKFYENFKPDIILLDIMLPIRDG
CEEEEEEECCHHHHHHHHHHHEECCEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCCCC
FEVAEAIRDYDSDIGIIMITAKGELESKVKGLKNADDYVVKPFEIEEILARIEALLKRMG
HHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
KTKELIKVGDIEIYPQNMEVLVNKKNVHLSLTEFNILKLLAINKNIVVSKEKILEEIWGY
CHHHHEEECCEEECCCCEEEEEECCCEEEEEEHHHEEEEEEECCCEEECHHHHHHHHCCC
YDEENNNLVEVYINYLRKKLKDSTQNIETVRGVGYVIREKESKT
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA