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The map label for this gene is alsA [C]

Identifier: 160877550

GI number: 160877550

Start: 5256060

End: 5257430

Strand: Reverse

Name: alsA [C]

Synonym: Sbal195_4449

Alternate gene names: 160877550

Gene position: 5257430-5256060 (Counterclockwise)

Preceding gene: 160877551

Following gene: 160877549

Centisome position: 98.32

GC content: 51.28

Gene sequence:

>1371_bases
ATGAAACTCCTAGCGCTCGAAGGCGTTAGCTTCAACTATGGCAGCCAGTTACCGACTGTATTGCAGGAGGTTAACTTGGC
GATTGGCACCGGCCAATGCCATTGCGTGAGCGGTCATACGGGCTCTGGGAAATCGAGTCTGCTAAACCTACTGGCGGGCG
TGTTAAATCGCCCGCATGAAGGTGACATCTGGCGTTACCCACAACTGGTTACGGGTCTGGTGATGCAGGACCCGCAAACC
CAGCTCCTTCGGCAAACCGTTGGCGCCGAAGTGGCTTTCGCCATAGAAAATCTTGGCATTCCCGCTGAGCAAATGCTACC
TAAAGTGCAATTGGCACTACGGCGCGTGGGCTTGTATCTGCGTCTCGATACACAAGTCAGCACGCTTTCCCTCGGTCAAA
AATATCGTTTAATGATTGCCGCCCAATTGGTGTGCGAGCCGCATTTACTGCTGCTCGATGAACCTTGGGCGCAACTCGAT
GATCACGGTGTGAGTGAGCTGCTGGTCGTACTTCGCAACCTTATTCAAGATGGCATGGCGCTAGTGTTGGTTGAACATAA
CGCCTCGGCCTTCGCTGAGATTATTCAGCATTACTGGCAGTTAGAGGCGGGCAAGCTATCCGAAGGCATCTATACCGTGA
ACGATGCGCCGCAAATTGAGGCGCCTGCGTGGCGAAATCAGCCTAAGTTTGAGCATTTGGGCAAAGTCTTGGTCAGCGCC
GAAGCCTTTGATTTTGGATTCGATGCTTGTCCCATTTTATTTGCGTGTCCGCACGGATTCCAACTGCAGGCGGGTGAGAT
AGTGACCTTAGTGGGAGATAACGGCTCAGGTAAAACTAGTTTGTTGAAAACCATAGCTGGCGTACTCAGTTCAAGGCAGC
GTCTTCCGCTTAAAGTGCTCGGGCGAAGACCTAAGTTGGGGATTTATGGCGCTGAGCTGGGTCTGCTGATGCAAAGGCCG
AGTCGACAATTATTCGAGACCAGCGTGCTCGCCGAAATGCAGTTTAGCCTTAGGCGTTTTGAACTCCCCAAAGAACGCGC
GGCGCAGATGTTGGATGAATTGGATTTATTTAGCTTAGCTCAGCTGTCGCCCCACAAATTATCCTACGGCCAACAGCACT
TGATTGCCTTAGCGTCACTCGCCTGTTTACGCCCTAAAGTATTGCTTTTGGACGATCCATTGGCGGGGATGGATAAGCAT
TACTACGGCAAAGTGTGGTACTTGCTGAAGCGGTTAAGCTCTCAAGGTTGCGCTATTTTGCTCAGCAGTCACAGAAGCAT
TGAACACAGCGCTGTATCACGGCAATTGAGTTTGCGTAATGGTTTATTGGTGGAGGAATTGATTGAAACAGGAGAGCGTT
ATGTGGGCTAG

Upstream 100 bases:

>100_bases
CTACGTGCGACTAACTTGCTGGATGAAAACTACTACCAGAGTGAAGCCCTGCCGCAGGCAGGACGACAGATCTTCATCGG
TGTGAACTGGCAGATCTAAG

Downstream 100 bases:

>100_bases
TTGTCGGCGCCTACGCGCGCTGCGGCATTGGAGTTATGAGCGGCGGGAAACGGCACTTTGTGCGTTGTCGCTGCTATTGG
TGTGCGTGCTCTCAGCCTGT

Product: ABC transporter-like protein

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKLLALEGVSFNYGSQLPTVLQEVNLAIGTGQCHCVSGHTGSGKSSLLNLLAGVLNRPHEGDIWRYPQLVTGLVMQDPQT
QLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRVGLYLRLDTQVSTLSLGQKYRLMIAAQLVCEPHLLLLDEPWAQLD
DHGVSELLVVLRNLIQDGMALVLVEHNASAFAEIIQHYWQLEAGKLSEGIYTVNDAPQIEAPAWRNQPKFEHLGKVLVSA
EAFDFGFDACPILFACPHGFQLQAGEIVTLVGDNGSGKTSLLKTIAGVLSSRQRLPLKVLGRRPKLGIYGAELGLLMQRP
SRQLFETSVLAEMQFSLRRFELPKERAAQMLDELDLFSLAQLSPHKLSYGQQHLIALASLACLRPKVLLLDDPLAGMDKH
YYGKVWYLLKRLSSQGCAILLSSHRSIEHSAVSRQLSLRNGLLVEELIETGERYVG

Sequences:

>Translated_456_residues
MKLLALEGVSFNYGSQLPTVLQEVNLAIGTGQCHCVSGHTGSGKSSLLNLLAGVLNRPHEGDIWRYPQLVTGLVMQDPQT
QLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRVGLYLRLDTQVSTLSLGQKYRLMIAAQLVCEPHLLLLDEPWAQLD
DHGVSELLVVLRNLIQDGMALVLVEHNASAFAEIIQHYWQLEAGKLSEGIYTVNDAPQIEAPAWRNQPKFEHLGKVLVSA
EAFDFGFDACPILFACPHGFQLQAGEIVTLVGDNGSGKTSLLKTIAGVLSSRQRLPLKVLGRRPKLGIYGAELGLLMQRP
SRQLFETSVLAEMQFSLRRFELPKERAAQMLDELDLFSLAQLSPHKLSYGQQHLIALASLACLRPKVLLLDDPLAGMDKH
YYGKVWYLLKRLSSQGCAILLSSHRSIEHSAVSRQLSLRNGLLVEELIETGERYVG
>Mature_456_residues
MKLLALEGVSFNYGSQLPTVLQEVNLAIGTGQCHCVSGHTGSGKSSLLNLLAGVLNRPHEGDIWRYPQLVTGLVMQDPQT
QLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRVGLYLRLDTQVSTLSLGQKYRLMIAAQLVCEPHLLLLDEPWAQLD
DHGVSELLVVLRNLIQDGMALVLVEHNASAFAEIIQHYWQLEAGKLSEGIYTVNDAPQIEAPAWRNQPKFEHLGKVLVSA
EAFDFGFDACPILFACPHGFQLQAGEIVTLVGDNGSGKTSLLKTIAGVLSSRQRLPLKVLGRRPKLGIYGAELGLLMQRP
SRQLFETSVLAEMQFSLRRFELPKERAAQMLDELDLFSLAQLSPHKLSYGQQHLIALASLACLRPKVLLLDDPLAGMDKH
YYGKVWYLLKRLSSQGCAILLSSHRSIEHSAVSRQLSLRNGLLVEELIETGERYVG

Specific function: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI215820660, Length=234, Percent_Identity=27.3504273504274, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI20143975, Length=234, Percent_Identity=27.3504273504274, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI46592898, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI46592915, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI46592978, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI46592956, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI46592964, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI46592971, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790525, Length=467, Percent_Identity=24.4111349036403, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788506, Length=514, Percent_Identity=26.4591439688716, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789991, Length=500, Percent_Identity=24.8, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790190, Length=431, Percent_Identity=23.8979118329466, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI48994943, Length=473, Percent_Identity=25.1585623678647, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787029, Length=255, Percent_Identity=29.0196078431373, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=30.3482587064677, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786563, Length=182, Percent_Identity=32.967032967033, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789873, Length=224, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=29.5774647887324, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787792, Length=456, Percent_Identity=24.5614035087719, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786975, Length=471, Percent_Identity=24.6284501061571, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786398, Length=213, Percent_Identity=29.5774647887324, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788225, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786872, Length=186, Percent_Identity=26.8817204301075, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787105, Length=208, Percent_Identity=29.8076923076923, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=197, Percent_Identity=29.4416243654822, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787164, Length=228, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786319, Length=205, Percent_Identity=28.2926829268293, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=190, Percent_Identity=31.0526315789474, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787089, Length=244, Percent_Identity=27.0491803278689, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082267, Length=168, Percent_Identity=29.7619047619048, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=31.2217194570136, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=162, Percent_Identity=33.9506172839506, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789963, Length=235, Percent_Identity=27.6595744680851, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=175, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076684, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581617, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581615, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076682, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574744, Length=188, Percent_Identity=29.2553191489362, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581191, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581189, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581193, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581195, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920532, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24580930, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574533, Length=330, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85724858, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85724856, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580547, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580551, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580549, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580545, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 50371; Mature: 50371

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLALEGVSFNYGSQLPTVLQEVNLAIGTGQCHCVSGHTGSGKSSLLNLLAGVLNRPHE
CEEEEECCCCCCCCCHHHHHHHHHHHEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCC
GDIWRYPQLVTGLVMQDPQTQLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRVGLYL
CCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHCCEEE
RLDTQVSTLSLGQKYRLMIAAQLVCEPHLLLLDEPWAQLDDHGVSELLVVLRNLIQDGMA
EECCCCHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHCCCEE
LVLVEHNASAFAEIIQHYWQLEAGKLSEGIYTVNDAPQIEAPAWRNQPKFEHLGKVLVSA
EEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
EAFDFGFDACPILFACPHGFQLQAGEIVTLVGDNGSGKTSLLKTIAGVLSSRQRLPLKVL
HHHCCCCCCCCCEEECCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHH
GRRPKLGIYGAELGLLMQRPSRQLFETSVLAEMQFSLRRFELPKERAAQMLDELDLFSLA
CCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QLSPHKLSYGQQHLIALASLACLRPKVLLLDDPLAGMDKHYYGKVWYLLKRLSSQGCAIL
HCCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEE
LSSHRSIEHSAVSRQLSLRNGLLVEELIETGERYVG
EECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLLALEGVSFNYGSQLPTVLQEVNLAIGTGQCHCVSGHTGSGKSSLLNLLAGVLNRPHE
CEEEEECCCCCCCCCHHHHHHHHHHHEEECCEEEEECCCCCCCHHHHHHHHHHHHCCCCC
GDIWRYPQLVTGLVMQDPQTQLLRQTVGAEVAFAIENLGIPAEQMLPKVQLALRRVGLYL
CCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHCCEEE
RLDTQVSTLSLGQKYRLMIAAQLVCEPHLLLLDEPWAQLDDHGVSELLVVLRNLIQDGMA
EECCCCHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCHHHHHHHHHHHHCCCEE
LVLVEHNASAFAEIIQHYWQLEAGKLSEGIYTVNDAPQIEAPAWRNQPKFEHLGKVLVSA
EEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
EAFDFGFDACPILFACPHGFQLQAGEIVTLVGDNGSGKTSLLKTIAGVLSSRQRLPLKVL
HHHCCCCCCCCCEEECCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHH
GRRPKLGIYGAELGLLMQRPSRQLFETSVLAEMQFSLRRFELPKERAAQMLDELDLFSLA
CCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QLSPHKLSYGQQHLIALASLACLRPKVLLLDDPLAGMDKHYYGKVWYLLKRLSSQGCAIL
HCCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEE
LSSHRSIEHSAVSRQLSLRNGLLVEELIETGERYVG
EECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]