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The map label for this gene is ykoW [H]

Identifier: 160877478

GI number: 160877478

Start: 5171170

End: 5173434

Strand: Direct

Name: ykoW [H]

Synonym: Sbal195_4376

Alternate gene names: 160877478

Gene position: 5171170-5173434 (Clockwise)

Preceding gene: 160877476

Following gene: 160877479

Centisome position: 96.71

GC content: 43.66

Gene sequence:

>2265_bases
TTGCTTCAATGGCTGAAAGGTTTTTTGTTTATTAGGGATCGAGACTTTTTAAATCCTGATAGAACAATATTAAAAACCAG
CTTATTGCGGATTATTCTGCTCAGTGGCGCGATGTTGACCGCTAGCATAGTGCTGCATAGCTCTTTAATTGCGTATCAGT
TAAACCTCGCTTTCATTATCAGCATTACGGTCAGTTTTTTAACCGTACTCTTCTTAACTTTATGGTTTACCGGCAAATAT
TTACTCGCCAGCTCAATCAGTCTGTTGGCTATGGTCATTGCCGCCTGCATTTCTATACTCTTGTTTGTCCCAGACTTTAA
CTTATCCCAGGCAGGTATTACCTTCTTATATACTCTTCCCTTAATGGCGCTTTTTCTATTTGGCAGAAAAGTAGCCGTTA
TTATGATGTTTTTTAATGTATTGCCTTTTCTACTGCTACTGCGTAACCAAAATATTCCCCCGATTATTGATATTGATATC
AGTCTGCCTGCAACCCACGCTTATCTGAATGGCTTGCTGTTTGTCTTTTTTAATATCTGTATTCCCTTGTCGGCGATGCG
CCTGCTAAAAACCCAGAAAGTCCATGCGCAGCAAATGATCCAGCATCAAAATGATCTGCAACGTACCTTAGATCAATATG
CTGAAATCTTTGAAAATAATGGTACCGCTTCCTTCTTCTGTAATGAGGACGGCGTGATTCTCAACCTGAATAATGCGGCC
AAAGAAATCGCCGGAGAGGTCACACTAAACCGCACTCGCCTATGTGACATTTTTGAACTTACCGAAGATACCAGCACAAA
TTTACTGGCGGCCGCGTTTCCGACCCATTTAAAGAACAATAACAGTATTAAATATCTGCTGCAGAAAGCCTCATTAGAGC
ACCATGACACTTTGTTGTTTCACTGCCACGATGTCACTGAACAGGCAAACCATGCGATTGAACTAAGCCGACTTAAAAAG
CACCATATCAGCACACATTTCTATGATTTAGTGACCGGATTACCCAACGAGAATCACTGGTATAACCCAGCCCCAAGTAC
GATCCATTTGGATATGACAGTCGCCTTAGTCAAAATTGATAATCTGAGTCAAATCAATGCCGCCTTCGGTATCAGCGTCG
GGGATGCCATCCTAAAAGCCTTTGCGACCGAACTCAAAAATCGCTTTGGTCATCACGCAAAAATATACCGGTTTAGGGGA
GCCTCGTTTGCGCTTGAGTTTACCAGCCTGCCGCTGATCTCCCCCGAAAACCTCGCGCTACAATTACGCGAGCGTATTCC
AACAAACCTGCAGCTTAAACATGAACAACAAATTGAATATCATCTCGAGTGCCGAGTCGGTTGCAGTTCGGGTAATAAAG
CCTCACCGCAGCAAGCCGCAGAGCAATGTTTAATTGCCATTAAGCAAACCACCCAAGCTAGCCCAGTCATGGTGTATTAC
ATTGGTTTGATTAATAATCTTCTCGAAGCCTCATCGCAGAAAGCCAAAATTCGCGACGCATTGAAACACAATCGTCTGGA
AATGTGGCTACAGCCTAAAGTAAGGGCAGATGGCCACATTATTAGCTTTGAAGCGCTGGCAAGAATGTTCGATGAAGACG
GCACTATGATTATGCCGAACACGTTTATTCCCATCATAGAGTCATCCCAATTACAGGCGATTTTTGCGATAAAAGTCTTC
AGGCAATTACTACAACTGATCCGTTCTTGGCCGAAAAACGTGCCTCTGGTCAGGATTGCCTTCAACTTATCTGGGCAAGA
TATTTTGTCGGATCGCTTCTTTAAGGTGTTGATCCAAACCTATATGAATCACCCCGAACTCATCCCATTATTAGAAATTG
AAATCACTGAAACCTCAGTATTTTCAACCCATAAAGAAACGGGCCGACGCCTAAACACCTTAGCTCGCATGGGAGTTTCT
ATCGCCATTGACGATTTTGGCACTGGCCATGCCTCATTAAGCCAACTCATCGATATCAGTGCCGACACGATAAAAATCGA
CCGCTGCTTTGTCAGTCAAATGGGCATTAGTGAACGCCATACCCAAATTGTCAACGCCGCCATCCTGTTAGCCAAGAGCT
TAAAACTCAACGTCATTGCCGAAGGTATAGAAACCGAAGCCCAGTTATTGCAACTCACGGCGTTAGGATGTGAACAATTT
CAAGGCTATCTATTCGGTAAACCCGCACCCGCGAATCTATGGCTGAAAACCTTTCAAATGCAAACGCCTACACACTGGTT
CGCCAATAAAAAGAGCGCCAACTGA

Upstream 100 bases:

>100_bases
ATAAAGATAGTAATCTATTTGTATAACAATTAAGTGATTTATGTTATATGTTATATCCCCAGTCAACCTGCGTGACTTCC
GTATGGGATAAGGACTCTTT

Downstream 100 bases:

>100_bases
GGCATTAAATTTACGCCTACAAGCATCGCAGGTATAATTGGCGTCAGGCATTTGCCTCTCTTTGCTTTGTTTGCAAATTA
CTAGGATCCCCCATGTTAAG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MLQWLKGFLFIRDRDFLNPDRTILKTSLLRIILLSGAMLTASIVLHSSLIAYQLNLAFIISITVSFLTVLFLTLWFTGKY
LLASSISLLAMVIAACISILLFVPDFNLSQAGITFLYTLPLMALFLFGRKVAVIMMFFNVLPFLLLLRNQNIPPIIDIDI
SLPATHAYLNGLLFVFFNICIPLSAMRLLKTQKVHAQQMIQHQNDLQRTLDQYAEIFENNGTASFFCNEDGVILNLNNAA
KEIAGEVTLNRTRLCDIFELTEDTSTNLLAAAFPTHLKNNNSIKYLLQKASLEHHDTLLFHCHDVTEQANHAIELSRLKK
HHISTHFYDLVTGLPNENHWYNPAPSTIHLDMTVALVKIDNLSQINAAFGISVGDAILKAFATELKNRFGHHAKIYRFRG
ASFALEFTSLPLISPENLALQLRERIPTNLQLKHEQQIEYHLECRVGCSSGNKASPQQAAEQCLIAIKQTTQASPVMVYY
IGLINNLLEASSQKAKIRDALKHNRLEMWLQPKVRADGHIISFEALARMFDEDGTMIMPNTFIPIIESSQLQAIFAIKVF
RQLLQLIRSWPKNVPLVRIAFNLSGQDILSDRFFKVLIQTYMNHPELIPLLEIEITETSVFSTHKETGRRLNTLARMGVS
IAIDDFGTGHASLSQLIDISADTIKIDRCFVSQMGISERHTQIVNAAILLAKSLKLNVIAEGIETEAQLLQLTALGCEQF
QGYLFGKPAPANLWLKTFQMQTPTHWFANKKSAN

Sequences:

>Translated_754_residues
MLQWLKGFLFIRDRDFLNPDRTILKTSLLRIILLSGAMLTASIVLHSSLIAYQLNLAFIISITVSFLTVLFLTLWFTGKY
LLASSISLLAMVIAACISILLFVPDFNLSQAGITFLYTLPLMALFLFGRKVAVIMMFFNVLPFLLLLRNQNIPPIIDIDI
SLPATHAYLNGLLFVFFNICIPLSAMRLLKTQKVHAQQMIQHQNDLQRTLDQYAEIFENNGTASFFCNEDGVILNLNNAA
KEIAGEVTLNRTRLCDIFELTEDTSTNLLAAAFPTHLKNNNSIKYLLQKASLEHHDTLLFHCHDVTEQANHAIELSRLKK
HHISTHFYDLVTGLPNENHWYNPAPSTIHLDMTVALVKIDNLSQINAAFGISVGDAILKAFATELKNRFGHHAKIYRFRG
ASFALEFTSLPLISPENLALQLRERIPTNLQLKHEQQIEYHLECRVGCSSGNKASPQQAAEQCLIAIKQTTQASPVMVYY
IGLINNLLEASSQKAKIRDALKHNRLEMWLQPKVRADGHIISFEALARMFDEDGTMIMPNTFIPIIESSQLQAIFAIKVF
RQLLQLIRSWPKNVPLVRIAFNLSGQDILSDRFFKVLIQTYMNHPELIPLLEIEITETSVFSTHKETGRRLNTLARMGVS
IAIDDFGTGHASLSQLIDISADTIKIDRCFVSQMGISERHTQIVNAAILLAKSLKLNVIAEGIETEAQLLQLTALGCEQF
QGYLFGKPAPANLWLKTFQMQTPTHWFANKKSAN
>Mature_754_residues
MLQWLKGFLFIRDRDFLNPDRTILKTSLLRIILLSGAMLTASIVLHSSLIAYQLNLAFIISITVSFLTVLFLTLWFTGKY
LLASSISLLAMVIAACISILLFVPDFNLSQAGITFLYTLPLMALFLFGRKVAVIMMFFNVLPFLLLLRNQNIPPIIDIDI
SLPATHAYLNGLLFVFFNICIPLSAMRLLKTQKVHAQQMIQHQNDLQRTLDQYAEIFENNGTASFFCNEDGVILNLNNAA
KEIAGEVTLNRTRLCDIFELTEDTSTNLLAAAFPTHLKNNNSIKYLLQKASLEHHDTLLFHCHDVTEQANHAIELSRLKK
HHISTHFYDLVTGLPNENHWYNPAPSTIHLDMTVALVKIDNLSQINAAFGISVGDAILKAFATELKNRFGHHAKIYRFRG
ASFALEFTSLPLISPENLALQLRERIPTNLQLKHEQQIEYHLECRVGCSSGNKASPQQAAEQCLIAIKQTTQASPVMVYY
IGLINNLLEASSQKAKIRDALKHNRLEMWLQPKVRADGHIISFEALARMFDEDGTMIMPNTFIPIIESSQLQAIFAIKVF
RQLLQLIRSWPKNVPLVRIAFNLSGQDILSDRFFKVLIQTYMNHPELIPLLEIEITETSVFSTHKETGRRLNTLARMGVS
IAIDDFGTGHASLSQLIDISADTIKIDRCFVSQMGISERHTQIVNAAILLAKSLKLNVIAEGIETEAQLLQLTALGCEQF
QGYLFGKPAPANLWLKTFQMQTPTHWFANKKSAN

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=425, Percent_Identity=27.5294117647059, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87081921, Length=428, Percent_Identity=24.7663551401869, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87082096, Length=394, Percent_Identity=27.9187817258883, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081743, Length=268, Percent_Identity=30.5970149253731, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=32.3404255319149, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI226510982, Length=251, Percent_Identity=29.4820717131474, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=30.5785123966942, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=29.5546558704453, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787055, Length=407, Percent_Identity=24.3243243243243, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=29.2, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081980, Length=238, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1787410, Length=115, Percent_Identity=35.6521739130435, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84980; Mature: 84980

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQWLKGFLFIRDRDFLNPDRTILKTSLLRIILLSGAMLTASIVLHSSLIAYQLNLAFII
CCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
SITVSFLTVLFLTLWFTGKYLLASSISLLAMVIAACISILLFVPDFNLSQAGITFLYTLP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LMALFLFGRKVAVIMMFFNVLPFLLLLRNQNIPPIIDIDISLPATHAYLNGLLFVFFNIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
IPLSAMRLLKTQKVHAQQMIQHQNDLQRTLDQYAEIFENNGTASFFCNEDGVILNLNNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECHHH
KEIAGEVTLNRTRLCDIFELTEDTSTNLLAAAFPTHLKNNNSIKYLLQKASLEHHDTLLF
HHHHCCEEECHHHHHHHHHHCCCCCCCEEEECCCHHCCCCCCHHHHHHHHCCCCCCEEEE
HCHDVTEQANHAIELSRLKKHHISTHFYDLVTGLPNENHWYNPAPSTIHLDMTVALVKID
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEC
NLSQINAAFGISVGDAILKAFATELKNRFGHHAKIYRFRGASFALEFTSLPLISPENLAL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCCCHHHH
QLRERIPTNLQLKHEQQIEYHLECRVGCSSGNKASPQQAAEQCLIAIKQTTQASPVMVYY
HHHHHCCCCEEECCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHH
IGLINNLLEASSQKAKIRDALKHNRLEMWLQPKVRADGHIISFEALARMFDEDGTMIMPN
HHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCCEECCC
TFIPIIESSQLQAIFAIKVFRQLLQLIRSWPKNVPLVRIAFNLSGQDILSDRFFKVLIQT
CCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
YMNHPELIPLLEIEITETSVFSTHKETGRRLNTLARMGVSIAIDDFGTGHASLSQLIDIS
HCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCC
ADTIKIDRCFVSQMGISERHTQIVNAAILLAKSLKLNVIAEGIETEAQLLQLTALGCEQF
CCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHCHHHH
QGYLFGKPAPANLWLKTFQMQTPTHWFANKKSAN
CCEECCCCCCCHHHEEEEECCCCCHHHCCCCCCC
>Mature Secondary Structure
MLQWLKGFLFIRDRDFLNPDRTILKTSLLRIILLSGAMLTASIVLHSSLIAYQLNLAFII
CCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
SITVSFLTVLFLTLWFTGKYLLASSISLLAMVIAACISILLFVPDFNLSQAGITFLYTLP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LMALFLFGRKVAVIMMFFNVLPFLLLLRNQNIPPIIDIDISLPATHAYLNGLLFVFFNIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
IPLSAMRLLKTQKVHAQQMIQHQNDLQRTLDQYAEIFENNGTASFFCNEDGVILNLNNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECHHH
KEIAGEVTLNRTRLCDIFELTEDTSTNLLAAAFPTHLKNNNSIKYLLQKASLEHHDTLLF
HHHHCCEEECHHHHHHHHHHCCCCCCCEEEECCCHHCCCCCCHHHHHHHHCCCCCCEEEE
HCHDVTEQANHAIELSRLKKHHISTHFYDLVTGLPNENHWYNPAPSTIHLDMTVALVKID
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEC
NLSQINAAFGISVGDAILKAFATELKNRFGHHAKIYRFRGASFALEFTSLPLISPENLAL
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCCCHHHH
QLRERIPTNLQLKHEQQIEYHLECRVGCSSGNKASPQQAAEQCLIAIKQTTQASPVMVYY
HHHHHCCCCEEECCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHH
IGLINNLLEASSQKAKIRDALKHNRLEMWLQPKVRADGHIISFEALARMFDEDGTMIMPN
HHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCCEECCC
TFIPIIESSQLQAIFAIKVFRQLLQLIRSWPKNVPLVRIAFNLSGQDILSDRFFKVLIQT
CCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
YMNHPELIPLLEIEITETSVFSTHKETGRRLNTLARMGVSIAIDDFGTGHASLSQLIDIS
HCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCC
ADTIKIDRCFVSQMGISERHTQIVNAAILLAKSLKLNVIAEGIETEAQLLQLTALGCEQF
CCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHCHHHH
QGYLFGKPAPANLWLKTFQMQTPTHWFANKKSAN
CCEECCCCCCCHHHEEEEECCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]