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The map label for this gene is phoP [H]

Identifier: 160877446

GI number: 160877446

Start: 5134087

End: 5134782

Strand: Direct

Name: phoP [H]

Synonym: Sbal195_4344

Alternate gene names: 160877446

Gene position: 5134087-5134782 (Clockwise)

Preceding gene: 160877445

Following gene: 160877447

Centisome position: 96.01

GC content: 48.28

Gene sequence:

>696_bases
ATGCGATTGTTATTGGTTGAAGATGATTTAGAACTGCAGGCTAACTTAAAACAACATCTGCTCGATGCCCATTACAGTAT
CGATGTGGCGAGCGATGGTGAAGAAGGCTTATTTCAAGCACTCGAATACAACTATGATGCGGCGATAATCGATGTCGGTT
TGCCTAAGCTCGATGGTATCGCGCTTATCCGCAGCGTACGCGAACAGGAACGCGACTTCCCAATCCTTATTTTAACCGCG
AGGGACAGTTGGCAAGATAAGGTGGAAGGGCTCGACGCCGGTGCCGACGACTACCTGACGAAACCTTTCCATCCCCAAGA
ACTGGTCGCGCGGCTAAAAGCCCTGATCCGTCGCTCTGCCGGCAAGGCCAGCCCTTTGATTTATAACGGTCCCTTTAGCC
TAAATACCAGCAGCTTAGAAGTGCGTAAAGGCGAAGAACTGGTTAACCTCAGCGGCTCTGAATACAAGTTATTCGAATTT
TTTATGCTGCATCAGGGTGAAGTGAAATCCAAAACCGTCCTCACAGAGCACATCTACGATCAGGATTTTGATTTAGATTC
AAACGTCATCGAAGTCTTTATCCGCCGGTTACGCAAAAAACTCGACCCTGATAATCAATACAACCTGATTGAAACCCTGC
GCGGCCAAGGTTATCGCCTAAAAGCGTTAACGCCCGAGCCAACTGCCGATGAGTAA

Upstream 100 bases:

>100_bases
CCAGCGGCTCAGGGTATCGGGTTAAGCTCCTCAATAATGATGGCCAAGTGTTTTCAGTCTCAGTGGATGCCGCAACTGGC
CGAGTGTCGAGGAACTAACT

Downstream 100 bases:

>100_bases
ACGTGCCATTGTGTGGCAAGTATTGAACTCCCTTAAAGCGCGCTTAGTGATTAGCGCGCTATTCTTTATCTTAGTGTTAT
TGCCTTTGATCGGCGTCGCC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGIALIRSVREQERDFPILILTA
RDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSAGKASPLIYNGPFSLNTSSLEVRKGEELVNLSGSEYKLFEF
FMLHQGEVKSKTVLTEHIYDQDFDLDSNVIEVFIRRLRKKLDPDNQYNLIETLRGQGYRLKALTPEPTADE

Sequences:

>Translated_231_residues
MRLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGIALIRSVREQERDFPILILTA
RDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSAGKASPLIYNGPFSLNTSSLEVRKGEELVNLSGSEYKLFEF
FMLHQGEVKSKTVLTEHIYDQDFDLDSNVIEVFIRRLRKKLDPDNQYNLIETLRGQGYRLKALTPEPTADE
>Mature_231_residues
MRLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGIALIRSVREQERDFPILILTA
RDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSAGKASPLIYNGPFSLNTSSLEVRKGEELVNLSGSEYKLFEF
FMLHQGEVKSKTVLTEHIYDQDFDLDSNVIEVFIRRLRKKLDPDNQYNLIETLRGQGYRLKALTPEPTADE

Specific function: Member of the two-component regulatory system phoQ/phoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=44.0366972477064, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.4449339207048, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=38.5650224215247, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=39.0909090909091, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=36.6071428571429, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=37.219730941704, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=29.7777777777778, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.5892857142857, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.8828828828829, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=32.034632034632, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.8777292576419, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=24.8908296943231, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=32.8358208955224, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=79, Percent_Identity=37.9746835443038, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26307; Mature: 26307

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGI
CEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
ALIRSVREQERDFPILILTARDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSA
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GKASPLIYNGPFSLNTSSLEVRKGEELVNLSGSEYKLFEFFMLHQGEVKSKTVLTEHIYD
CCCCCEEECCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCC
QDFDLDSNVIEVFIRRLRKKLDPDNQYNLIETLRGQGYRLKALTPEPTADE
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRLLLVEDDLELQANLKQHLLDAHYSIDVASDGEEGLFQALEYNYDAAIIDVGLPKLDGI
CEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHH
ALIRSVREQERDFPILILTARDSWQDKVEGLDAGADDYLTKPFHPQELVARLKALIRRSA
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GKASPLIYNGPFSLNTSSLEVRKGEELVNLSGSEYKLFEFFMLHQGEVKSKTVLTEHIYD
CCCCCEEECCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCC
QDFDLDSNVIEVFIRRLRKKLDPDNQYNLIETLRGQGYRLKALTPEPTADE
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA