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The map label for this gene is aaeR [H]

Identifier: 160877344

GI number: 160877344

Start: 5020799

End: 5021800

Strand: Direct

Name: aaeR [H]

Synonym: Sbal195_4242

Alternate gene names: 160877344

Gene position: 5020799-5021800 (Clockwise)

Preceding gene: 160877342

Following gene: 160877345

Centisome position: 93.89

GC content: 49.6

Gene sequence:

>1002_bases
ATGATCAAAGGCATGATCGTTTTTGCGGCAATCGCAGAAAAGGGTTCAATGAGTGCCGCGGCGCAGCAGTTAAACCTCAG
CTCCTCGGCGGTGAGTCAACAAGTGACTAAGCTCGAAATGGACATGGGGATCAGTCTATTCCACCGCAATACTCGCAATC
TTACCCTCACAGAAGCGGGCAGCTTGTTCTATGAGAATTGCCGAAAAGTCATCGCGATAGTCGAAAACACAGAGCAAAAA
CTCAATAACTTGAAAGGGATTCCTTCGGGGGAATTAAAGATTGCCGCGCCCATAGGTTTTGGCGGCGGCCTATTGAGTGA
GCCCTTTAACTACCTGTTGGCGGCGCATCCGCAGATAAGTTTGAATTTACTGCTGCAGGATGGCCCGATAGATATAGTCA
ACGAGGGCATAGATCTGGCGATTTGCATCGGTCCTTTATCAGACTCCAACTTAATTGCCCGCCACTTAGCCGATTGGCGC
ATGTTGCTGTGCGCCTCACCCGATTATTTGCCAATGCACAAAATTTTTAAGCATCCCGCTGAATTGGCGGCCTTTAATCG
CATTAATCACCCCTGCGCTAACAGTGAAACCTTGACCCATGCCCGCAGCCAAGAGTGCTTCGAGCTGACAAGTCAGCGCA
TTACCGTCAACAATATGCAGGCATTAATCCAACTCACTCTCGATGGTCTCGGGTTTGCCGCCCTGCCCGAACCTGAAGTG
CATAAATACCTCGAAAGCGGCCAGCTTGTGACCCTCTTACCCGAATGGTCACTCAATACTTACAGCGTTTACAGCGTCAC
TTCGGCGCGGGATAAGCAGCCCGCAAAAGTGAAAGAAGCGCTCAATACACTTAGCCAATACTTCAGTCAGGCGGATTTTA
CCCCTGCCGTTCAATCTAAACAGCCTGTTCAAAATGGTGGCACAAAGGATTGCGTGACCAATATTTTACCCATAAAGCCC
AAGCAAGCGTCCCATCACACCAACGTCGATCACGCATCTTAA

Upstream 100 bases:

>100_bases
AGAACAATTTTCAATACGGCAATGTATCCCTATGTTACAATCAGCTCAAGTTAGACTTTAGGTATTCACTTGTAAGAGTT
ACTTAAAAATGAATAAAAAC

Downstream 100 bases:

>100_bases
GTGTGCCTTTTGCGCATTCATTTCTGCGCTAAGCTGGGGTATTCTGCTGGGATGAACCGATAAAAAGATGTAACTCGATG
AAAGATGTGGCCTTAGTGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIKGMIVFAAIAEKGSMSAAAQQLNLSSSAVSQQVTKLEMDMGISLFHRNTRNLTLTEAGSLFYENCRKVIAIVENTEQK
LNNLKGIPSGELKIAAPIGFGGGLLSEPFNYLLAAHPQISLNLLLQDGPIDIVNEGIDLAICIGPLSDSNLIARHLADWR
MLLCASPDYLPMHKIFKHPAELAAFNRINHPCANSETLTHARSQECFELTSQRITVNNMQALIQLTLDGLGFAALPEPEV
HKYLESGQLVTLLPEWSLNTYSVYSVTSARDKQPAKVKEALNTLSQYFSQADFTPAVQSKQPVQNGGTKDCVTNILPIKP
KQASHHTNVDHAS

Sequences:

>Translated_333_residues
MIKGMIVFAAIAEKGSMSAAAQQLNLSSSAVSQQVTKLEMDMGISLFHRNTRNLTLTEAGSLFYENCRKVIAIVENTEQK
LNNLKGIPSGELKIAAPIGFGGGLLSEPFNYLLAAHPQISLNLLLQDGPIDIVNEGIDLAICIGPLSDSNLIARHLADWR
MLLCASPDYLPMHKIFKHPAELAAFNRINHPCANSETLTHARSQECFELTSQRITVNNMQALIQLTLDGLGFAALPEPEV
HKYLESGQLVTLLPEWSLNTYSVYSVTSARDKQPAKVKEALNTLSQYFSQADFTPAVQSKQPVQNGGTKDCVTNILPIKP
KQASHHTNVDHAS
>Mature_333_residues
MIKGMIVFAAIAEKGSMSAAAQQLNLSSSAVSQQVTKLEMDMGISLFHRNTRNLTLTEAGSLFYENCRKVIAIVENTEQK
LNNLKGIPSGELKIAAPIGFGGGLLSEPFNYLLAAHPQISLNLLLQDGPIDIVNEGIDLAICIGPLSDSNLIARHLADWR
MLLCASPDYLPMHKIFKHPAELAAFNRINHPCANSETLTHARSQECFELTSQRITVNNMQALIQLTLDGLGFAALPEPEV
HKYLESGQLVTLLPEWSLNTYSVYSVTSARDKQPAKVKEALNTLSQYFSQADFTPAVQSKQPVQNGGTKDCVTNILPIKP
KQASHHTNVDHAS

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=31.1643835616438, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=31.5254237288136, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=29.2929292929293, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI145693193, Length=283, Percent_Identity=28.9752650176678, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789440, Length=272, Percent_Identity=28.6764705882353, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787128, Length=256, Percent_Identity=27.734375, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=26.2962962962963, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788706, Length=284, Percent_Identity=24.6478873239437, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790011, Length=302, Percent_Identity=23.841059602649, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790783, Length=271, Percent_Identity=25.4612546125461, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=24.21875, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=240, Percent_Identity=24.1666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=209, Percent_Identity=28.7081339712919, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082024, Length=252, Percent_Identity=24.2063492063492, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786713, Length=254, Percent_Identity=25.5905511811024, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36385; Mature: 36385

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGMIVFAAIAEKGSMSAAAQQLNLSSSAVSQQVTKLEMDMGISLFHRNTRNLTLTEAG
CCCCEEEEEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHH
SLFYENCRKVIAIVENTEQKLNNLKGIPSGELKIAAPIGFGGGLLSEPFNYLLAAHPQIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEE
LNLLLQDGPIDIVNEGIDLAICIGPLSDSNLIARHLADWRMLLCASPDYLPMHKIFKHPA
EEEEEECCCCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCHHHHHHCHH
ELAAFNRINHPCANSETLTHARSQECFELTSQRITVNNMQALIQLTLDGLGFAALPEPEV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCCCCHHH
HKYLESGQLVTLLPEWSLNTYSVYSVTSARDKQPAKVKEALNTLSQYFSQADFTPAVQSK
HHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
QPVQNGGTKDCVTNILPIKPKQASHHTNVDHAS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKGMIVFAAIAEKGSMSAAAQQLNLSSSAVSQQVTKLEMDMGISLFHRNTRNLTLTEAG
CCCCEEEEEEHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHH
SLFYENCRKVIAIVENTEQKLNNLKGIPSGELKIAAPIGFGGGLLSEPFNYLLAAHPQIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEE
LNLLLQDGPIDIVNEGIDLAICIGPLSDSNLIARHLADWRMLLCASPDYLPMHKIFKHPA
EEEEEECCCCHHHCCCCEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCHHHHHHCHH
ELAAFNRINHPCANSETLTHARSQECFELTSQRITVNNMQALIQLTLDGLGFAALPEPEV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCCCCCCHHH
HKYLESGQLVTLLPEWSLNTYSVYSVTSARDKQPAKVKEALNTLSQYFSQADFTPAVQSK
HHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
QPVQNGGTKDCVTNILPIKPKQASHHTNVDHAS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]