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The map label for this gene is coaE [H]

Identifier: 160877167

GI number: 160877167

Start: 4796753

End: 4797370

Strand: Direct

Name: coaE [H]

Synonym: Sbal195_4063

Alternate gene names: 160877167

Gene position: 4796753-4797370 (Clockwise)

Preceding gene: 160877166

Following gene: 160877168

Centisome position: 89.7

GC content: 46.6

Gene sequence:

>618_bases
ATGTCAAAGTTTGTCGTTGGCCTTACAGGCGGTATTGGCAGCGGTAAAACAACGGTTGCCAATTTATTCGCCGCCGAAGG
GATTACCTTAGTCGACGCAGATATTGTTGCCCGCGAGGTCGTCGCTCCGGGTTCAAAAGGACTGGAAGCGATCGTAACTC
ATTTTGGTGCTGAGATATTAACACCAGAGGGTGAACTCGATCGCGCCAAGTTGCGGCAGCGGATATTTAGCCATCCAGAA
GAGCGTGAATGGCTAAACCAACTATTACACCCCATGATCCGCCAAGAAATGCTAGCGCAGGTAGAAAAAGCGACCTCGGC
CTATGTAATTATGGTCGTGCCCTTGCTATTTGAGAACGGGTTAGATAGGTTAGTCAATCGGACTTTAGTGGTGGATATTT
CGCCTGAGTTGCAAGTAAATCGCACCGTAAAACGTGACAATGTTGATGCATCTCAAGTTAATAACATCATTAGTAGCCAA
TGTAGTCGCAGCGAAAAACTCGCCAGAGCCGACGACATTATTGATAATCAAGGAGAGATATCAACCTTAAAACGAGAGGT
GCTAGCATTGCACCAGCGATATTTACAACTTTCTGGTACTGATAACGCCCATGACTGA

Upstream 100 bases:

>100_bases
AGGCTGGATAGCCTTGCTATTTGGACAGCAGATTGTCGATTGGTACCTATCAACACTGTAAAAGCATGCAAACTAAGCAC
AAAGCTATCCGGAGTATGTT

Downstream 100 bases:

>100_bases
ATTAGTTTACGAACAGCCCCTAAACGAGAAAATTCGCAGCTACTTGCGGCTCGAATACCTCGATAAACAGCTGCAAAGTA
ACCTAAATCATGACCACCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSKFVVGLTGGIGSGKTTVANLFAAEGITLVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPE
EREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQVNRTVKRDNVDASQVNNIISSQ
CSRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD

Sequences:

>Translated_205_residues
MSKFVVGLTGGIGSGKTTVANLFAAEGITLVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPE
EREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQVNRTVKRDNVDASQVNNIISSQ
CSRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD
>Mature_204_residues
SKFVVGLTGGIGSGKTTVANLFAAEGITLVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPEE
REWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQVNRTVKRDNVDASQVNNIISSQC
SRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=38.0208333333333, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=38.0208333333333, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI110227607, Length=188, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI110227605, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227603, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227601, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI205277394, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=53.5714285714286, Blast_Score=215, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=41.4893617021277, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25143409, Length=165, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=192, Percent_Identity=36.9791666666667, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=32.8125, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24658602, Length=185, Percent_Identity=28.1081081081081, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22608; Mature: 22477

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFVVGLTGGIGSGKTTVANLFAAEGITLVDADIVAREVVAPGSKGLEAIVTHFGAEIL
CCCEEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHCCHHC
TPEGELDRAKLRQRIFSHPEEREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQVNRTVKRDNVDASQVNNIISSQCSRSEKLARADDIIDNQGEI
HHHHHCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
STLKREVLALHQRYLQLSGTDNAHD
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKFVVGLTGGIGSGKTTVANLFAAEGITLVDADIVAREVVAPGSKGLEAIVTHFGAEIL
CCEEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHCCHHC
TPEGELDRAKLRQRIFSHPEEREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQVNRTVKRDNVDASQVNNIISSQCSRSEKLARADDIIDNQGEI
HHHHHCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
STLKREVLALHQRYLQLSGTDNAHD
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]