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The map label for this gene is alsR [H]

Identifier: 160877092

GI number: 160877092

Start: 4694169

End: 4695050

Strand: Reverse

Name: alsR [H]

Synonym: Sbal195_3988

Alternate gene names: 160877092

Gene position: 4695050-4694169 (Counterclockwise)

Preceding gene: 160877093

Following gene: 160877088

Centisome position: 87.8

GC content: 44.56

Gene sequence:

>882_bases
TTGAATATTCAACGAGTTAAAGCATTTGTATTGACGACTCAACTAGGCTCAGTTTCAGCCGCCGCTCGCGCTCTGGGAAA
ACGTCAGCCGCAAGTGAGTCAGTGGATTGCCGATCTAGAAGTCGACATCGGTGTGGATTTATTTGAGCGTAGTGCAAATC
AAGTGGCACTCACTGCGGGAGGTGAGCATTTACTACCTAAGGCTATTTTAGCCTTGGCCCAATGGGAACAATTTACTCAA
TCGGCGACCCATTATGCTGAGCTTGGTAAAGGTCGGTTAGTGTTGGGGGTTGAAAATTATATTCCTTTAGAAGTCTTACG
TTCGACGATTCAGCGCTATTTAATGCAGTTTCCAACGCTGGATTTTGTCCTAAAAGTGGATACTTTCGATGCTTTACACA
GCGCTTTTTTATCCAATGATATCGACCTTTTACTGTTACATGAAACGGTTGAATTACATCAATCTCAATCGGGTTACTGC
CGCCTTGGCGAATATCAAGAGGTAATGTTGATATCTGGACAGCATGCATTAGCTTCACAGCAGGTAATCGACCCCGCACA
ATTAGCGCCCTATCGTGAATATATTTGGGCAGGAGGGCAGACTGAAAGTGATGATCTCGAAGTCGGATTTAGTGGCCATT
ATTGCCAAATCCCCGATCTTGCTTTGTTAAAGTCCTTACTTGCCGAAGGGGATGGATATAGTTTTTTGCCGTTATCTTTA
GCGCAGACAGAAATCGACAGTGGAAGATTAAAAGTTGTCCAATTGAGTAGTGAATTTGCGCCTATGAAGCGGCGGCTCGA
AATGCGCTGGCATCATGGGTTTGAGGCCAGCACCTTAGGGTCTTCTTTGCTGACGTTAATAAAAGAGCAACTCAGCAAAT
AA

Upstream 100 bases:

>100_bases
TTTTAACAAAGTGTCTTGCATAGGTAAGTTAATGTTGTGATTCCGTCTGACGGGTATTAAAGTCAAGTGCACAACGCGCT
TATAAAATAGTAGAGCACAT

Downstream 100 bases:

>100_bases
TTAGATTGATACGGGATTGCTATTGATCATTGAGATCGAACACTAGCTCCCCCTCTAACCACGTCATTAAAATTTGAGTG
TCAGCAATTTGTTTTGCTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNIQRVKAFVLTTQLGSVSAAARALGKRQPQVSQWIADLEVDIGVDLFERSANQVALTAGGEHLLPKAILALAQWEQFTQ
SATHYAELGKGRLVLGVENYIPLEVLRSTIQRYLMQFPTLDFVLKVDTFDALHSAFLSNDIDLLLLHETVELHQSQSGYC
RLGEYQEVMLISGQHALASQQVIDPAQLAPYREYIWAGGQTESDDLEVGFSGHYCQIPDLALLKSLLAEGDGYSFLPLSL
AQTEIDSGRLKVVQLSSEFAPMKRRLEMRWHHGFEASTLGSSLLTLIKEQLSK

Sequences:

>Translated_293_residues
MNIQRVKAFVLTTQLGSVSAAARALGKRQPQVSQWIADLEVDIGVDLFERSANQVALTAGGEHLLPKAILALAQWEQFTQ
SATHYAELGKGRLVLGVENYIPLEVLRSTIQRYLMQFPTLDFVLKVDTFDALHSAFLSNDIDLLLLHETVELHQSQSGYC
RLGEYQEVMLISGQHALASQQVIDPAQLAPYREYIWAGGQTESDDLEVGFSGHYCQIPDLALLKSLLAEGDGYSFLPLSL
AQTEIDSGRLKVVQLSSEFAPMKRRLEMRWHHGFEASTLGSSLLTLIKEQLSK
>Mature_293_residues
MNIQRVKAFVLTTQLGSVSAAARALGKRQPQVSQWIADLEVDIGVDLFERSANQVALTAGGEHLLPKAILALAQWEQFTQ
SATHYAELGKGRLVLGVENYIPLEVLRSTIQRYLMQFPTLDFVLKVDTFDALHSAFLSNDIDLLLLHETVELHQSQSGYC
RLGEYQEVMLISGQHALASQQVIDPAQLAPYREYIWAGGQTESDDLEVGFSGHYCQIPDLALLKSLLAEGDGYSFLPLSL
AQTEIDSGRLKVVQLSSEFAPMKRRLEMRWHHGFEASTLGSSLLTLIKEQLSK

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082024, Length=259, Percent_Identity=27.4131274131274, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32585; Mature: 32585

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQRVKAFVLTTQLGSVSAAARALGKRQPQVSQWIADLEVDIGVDLFERSANQVALTAG
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEECC
GEHLLPKAILALAQWEQFTQSATHYAELGKGRLVLGVENYIPLEVLRSTIQRYLMQFPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCE
DFVLKVDTFDALHSAFLSNDIDLLLLHETVELHQSQSGYCRLGEYQEVMLISGQHALASQ
EEEEEECHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCEECCCCCEEEEECCCHHHHHH
QVIDPAQLAPYREYIWAGGQTESDDLEVGFSGHYCQIPDLALLKSLLAEGDGYSFLPLSL
HCCCHHHHCCHHHHHCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHCCCCCEEEEHHH
AQTEIDSGRLKVVQLSSEFAPMKRRLEMRWHHGFEASTLGSSLLTLIKEQLSK
HHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIQRVKAFVLTTQLGSVSAAARALGKRQPQVSQWIADLEVDIGVDLFERSANQVALTAG
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEECC
GEHLLPKAILALAQWEQFTQSATHYAELGKGRLVLGVENYIPLEVLRSTIQRYLMQFPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCE
DFVLKVDTFDALHSAFLSNDIDLLLLHETVELHQSQSGYCRLGEYQEVMLISGQHALASQ
EEEEEECHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCEECCCCCEEEEECCCHHHHHH
QVIDPAQLAPYREYIWAGGQTESDDLEVGFSGHYCQIPDLALLKSLLAEGDGYSFLPLSL
HCCCHHHHCCHHHHHCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHHCCCCCEEEEHHH
AQTEIDSGRLKVVQLSSEFAPMKRRLEMRWHHGFEASTLGSSLLTLIKEQLSK
HHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]