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The map label for this gene is hupB [H]

Identifier: 160877047

GI number: 160877047

Start: 4645865

End: 4646137

Strand: Direct

Name: hupB [H]

Synonym: Sbal195_3943

Alternate gene names: 160877047

Gene position: 4645865-4646137 (Clockwise)

Preceding gene: 160877046

Following gene: 160877048

Centisome position: 86.88

GC content: 45.79

Gene sequence:

>273_bases
ATGAACAAAACTGAACTTATCGCCAAAATTGCAGAAAATGCCGATCTAACGAAAGTAGAAGCCGCACGCGCATTGAAGTC
TTTTGAAGCAGCCATTACCGAATCAATGAAAAATGGTGACAAAATCTCCATCGTAGGCTTCGGTTCGTTTGAAACTGCGA
CTCGTGCCGCTCGCACCGGCCGTAACCCACAAACGGGTAAAGAAATTCAAATCGCTGAAGCGACTGTACCTAAGTTTAAA
GCGGGTAAGACCCTACGCGACAGCGTAAACTAA

Upstream 100 bases:

>100_bases
TCCGGCACCTTAGACGCAAAAGGCTTTCCAAGCGCTAAACCTTATGGCATGTTAGGCACGCTTATTTCAAATAAATCTAC
GGAAAGAAGAGACAATAAAA

Downstream 100 bases:

>100_bases
GCTAGAAAATTCAAAACAACGCCTCCATTGTGAGGCGTTTTTTTTGCCCTATCCCAGTGAAACGCTGAATATTTTTTGCA
CAACAAGAGTGCGCCTCTGC

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTGRNPQTGKEIQIAEATVPKFK
AGKTLRDSVN

Sequences:

>Translated_90_residues
MNKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTGRNPQTGKEIQIAEATVPKFK
AGKTLRDSVN
>Mature_90_residues
MNKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTGRNPQTGKEIQIAEATVPKFK
AGKTLRDSVN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=61.1111111111111, Blast_Score=116, Evalue=3e-28,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=61.7977528089888, Blast_Score=110, Evalue=2e-26,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=39.5604395604396, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9655; Mature: 9655

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTG
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCC
RNPQTGKEIQIAEATVPKFKAGKTLRDSVN
CCCCCCCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKTELIAKIAENADLTKVEAARALKSFEAAITESMKNGDKISIVGFGSFETATRAARTG
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCC
RNPQTGKEIQIAEATVPKFKAGKTLRDSVN
CCCCCCCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]