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The map label for this gene is yisQ [H]

Identifier: 160876883

GI number: 160876883

Start: 4453856

End: 4455217

Strand: Reverse

Name: yisQ [H]

Synonym: Sbal195_3779

Alternate gene names: 160876883

Gene position: 4455217-4453856 (Counterclockwise)

Preceding gene: 160876885

Following gene: 160876881

Centisome position: 83.32

GC content: 50.44

Gene sequence:

>1362_bases
GTGGCTAAAGCACCTAAAACATTGCAACAACGCATGAGCATAGTCGCCCTCACTTGGCCGATTTTTGTCGAGACCTTGCT
GCAATCACTGCTTGGGATCAGCGACATTTTTATGCTCAGCCATTATTCCGATAACGCGGTAGCGGCAGTGGGACTCACGA
CTCAGCTGATGTTCTTCATGATGGTCATGTCCATGATGGTGAGCACAGGTGCGAGCATTTTGATTAGCCAGAACAATGGT
GCAGGCCAGTCGCAACAGGCTGTCGATATCGGGGTGGCAAGTGTCGCATTGAGCTTAGGACTCGCCTTGATCATGGGCGC
CTCTATGTTCTTCGGTGCTAAGGGGATTATCGGCCTATTTGCACTTGAACACGATGTGGCAGGCTTTGGATATGACTATT
TAGTGATTTGCGGCAGCTTGAGTATAGGCTTGGTCATGAATATCGCTTTTGCCGCGATTTTAAGGAGTTACGGCTTTACC
CGCTCGGCTATGCTCGTCACCTCAAGCACAGGCTTGATGAACGTCATCGGTAATTATATTGCCCTGTATTCTCCCTTTGG
TTTACCTGTTTATGGGGTAACAGGGGTGGCTATTTCCACCGTCACCAGCCAGATCATCGGTGCCGTGATCATGCTGATGG
TGATCCGCTATAAAAAGATCCCGCTGCCACTGCAACGGCTTAAATTATTACCGCGCAGCACCTATTGGAGCGTGATGCGT
ATCGGCTTGCTCAATGCCGGTGAGATGTTGTCTTACAATGTGGCGCAGATGACCATCATCTATTTTATCAGTCAGATGGG
GACGTTATCGCTCACGGCTTATACCTATGGCCTAAACATCAGCCGGTTTATTTATTGTTTTGCGGTGGCGCTCGGGCAGG
CGACGCAAATTCAGACCGGGTACTATGTCGGCAAACAATGGTTCGATGAAATCACTGTGAGAGTGCAACGTTACTGTCTG
GTGGGTTTTATCGCTTCGCTGGTCATAGTCTTAGTCTTCTACTGGCAGCGATTCACTATCGTTGGCTGGCTTAGTGAGAA
CGAGGAAGTCATCCAACTGACGGCGTTATTACTGGCAGGTTCTATCGCGCTTGAAACGGGGCGGGTGTTTAATCTGGTGA
TTATTTCGGCATTAAAAGGGGCGGGTGATGTGGCGTTCCCAGTACGGGTTGGCCTCTTTAGCATGTGGGGCATAGGGGTA
TTATTGGCTTGGTTCTTTGGCCTTCACTTAGGTTATGGCGTACTCGCCGCTTGGCTTGCCGTCGCCGCAGATGAATGGAT
ACGCGGCCTGATTATGGTATACCGCTGGCGCTCGGGTCGCTGGCAGCGTTTTACTCGAATACCCGCTGTGACTGCAGTGT
AA

Upstream 100 bases:

>100_bases
CAGTCTCTTGGCTAAAATATAGGTTGCCAAGATACCGTTTGAGCGACACATTGAGCCAGCGCTCACATCGTTATCCGTAC
TCTATTTGCAGGAATTCTCC

Downstream 100 bases:

>100_bases
TTTTGGTGAGGTGAATTGGAAGCGCAGCAAACATAGGCTGCGCTTTTTGTTTGATAAGCTTAACTTTGCTGCTTCAACAA
GGTACGACATAGCTTGATAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNG
AGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFT
RSAMLVTSSTGLMNVIGNYIALYSPFGLPVYGVTGVAISTVTSQIIGAVIMLMVIRYKKIPLPLQRLKLLPRSTYWSVMR
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITVRVQRYCL
VGFIASLVIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGV
LLAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSGRWQRFTRIPAVTAV

Sequences:

>Translated_453_residues
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNG
AGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFT
RSAMLVTSSTGLMNVIGNYIALYSPFGLPVYGVTGVAISTVTSQIIGAVIMLMVIRYKKIPLPLQRLKLLPRSTYWSVMR
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITVRVQRYCL
VGFIASLVIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGV
LLAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSGRWQRFTRIPAVTAV
>Mature_452_residues
AKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNGA
GQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTR
SAMLVTSSTGLMNVIGNYIALYSPFGLPVYGVTGVAISTVTSQIIGAVIMLMVIRYKKIPLPLQRLKLLPRSTYWSVMRI
GLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITVRVQRYCLV
GFIASLVIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVL
LAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSGRWQRFTRIPAVTAV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=468, Percent_Identity=23.5042735042735, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49546; Mature: 49414

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHHH
MVMSMMVSTGASILISQNNGAGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVIGNYI
HHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
ALYSPFGLPVYGVTGVAISTVTSQIIGAVIMLMVIRYKKIPLPLQRLKLLPRSTYWSVMR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHH
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECC
YYVGKQWFDEITVRVQRYCLVGFIASLVIVLVFYWQRFTIVGWLSENEEVIQLTALLLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
SIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVLLAWFFGLHLGYGVLAAWLA
HHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAADEWIRGLIMVYRWRSGRWQRFTRIPAVTAV
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHHH
MVMSMMVSTGASILISQNNGAGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVIGNYI
HHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
ALYSPFGLPVYGVTGVAISTVTSQIIGAVIMLMVIRYKKIPLPLQRLKLLPRSTYWSVMR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHH
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECC
YYVGKQWFDEITVRVQRYCLVGFIASLVIVLVFYWQRFTIVGWLSENEEVIQLTALLLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
SIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVLLAWFFGLHLGYGVLAAWLA
HHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAADEWIRGLIMVYRWRSGRWQRFTRIPAVTAV
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]