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The map label for this gene is fabB [H]

Identifier: 160875950

GI number: 160875950

Start: 3382304

End: 3383539

Strand: Reverse

Name: fabB [H]

Synonym: Sbal195_2840

Alternate gene names: 160875950

Gene position: 3383539-3382304 (Counterclockwise)

Preceding gene: 160875952

Following gene: 160875949

Centisome position: 63.28

GC content: 48.3

Gene sequence:

>1236_bases
ATGTACACAATGGATAGCAATAAAATGAAAAGAGTCGTGATCACCGGAATGGGTGTTGTTTCAAGTATCGGTAATAACAA
GCAAGAAGTGACCGAGTCACTGAAAGCGGGCCGCAGTGGTATTACGCATTCAGCTCAGTTTGAAGAGATGCAGTTACGTA
GCCACGTATGGGGTGACATCAAGTTAAACCCTGCTGAGCATATCGATCGTAAAGCGCTACGCTTCATGGGCGATGCCGCT
GCCTATGCTTACATTGCGATGCAAGAAGCCGTTAGCGATGCCAATTTAACTGAAGAGCAGTATTCAGATCCGCGCGTCGG
TTTGATTGTCGGTACAGGCGGCGCATCATCGTCTAACCAAGTACAATCTGCCGATACACTGCGTGAAAAAGGCGTTAAAC
GTGTTGGTCCGTATATTGTGCCTCGCATCATGTCGAGCACGGCCAGCGCTTGTTTAGCCACACCATTTAAAATTAAAGGC
ATGAATTATTCTATCAGTTCAGCCTGTGCAACCAGCGCCCACTGTATTGGTCACGCCGTTGAACTTATCCAAATGGGTAA
GCAAGACATGGTGTTTGCCGGTGGTGCTGAAGAAGTGGATTGGACGCTGACCATGGGCTTTGATGCTATGGGCGCACTGT
CAACTAAGTACAATGCCACACCAGAAAAAGCCTCTCGTACCTATGATGCAGACCGTGATGGTTTTGTGATCTCTGGCGGC
GGCGGTATTTTAGTGGTTGAAGAGTTAGAGCATGCTCTGGCTCGCGGCGCAAAAATTTACGCTGAAGTGATTGGTTATGG
CGCGTCTTCAGACGGTTATGACATGGTAGCGCCATCTGGCGAAGGCGCAGTGCGTTGTATGCAAATGGCGATGATGGATG
TCGATACCCCAATCGATTACATCAACACTCACGGCACTTCAACGCCAGTGGGCGACGTGCGCGAATTAGAAGCGCTACGT
GAAGTTTTCAAAGACAAGTGCCCACCGATTGCATCGACTAAGTCTATGACAGGTCATGCATTAGGCGCTGCAGGCGTACA
TGAAGCGATTTACAGCTTAATCATGATGGAAAACAGCTTTATTGCCCCAAGCATCAATATCGAAAATCTGGACGACGCGG
CGAAAGATATGCCTATCGTGCGTGAATATCGCGATGCTGAGCTGAATACAGTCATGAGTAACAGCTTTGGTTTTGGCGGT
ACAAACGCCACGCTAGTGATGCGTAAATTCAAATAA

Upstream 100 bases:

>100_bases
GGTCTCATAATTGGCATTATTTTACTCGCCTTTATGGAAAGCTGACCACTTAATTGAGTCAAAACAGATACTATTGGCTC
AGCGAAAAGTAGGTACTGAC

Downstream 100 bases:

>100_bases
GTTTGTTTATCAAACGCGATAGAAGGGAAGCTTAGGCTTCCCTTTTTTATGGGCGTTTTATGTGAACCTGTTGCATAGGC
AGGGATTTATCCCATTAGTC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase I; Beta-ketoacyl-ACP synthase I; KAS I [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MYTMDSNKMKRVVITGMGVVSSIGNNKQEVTESLKAGRSGITHSAQFEEMQLRSHVWGDIKLNPAEHIDRKALRFMGDAA
AYAYIAMQEAVSDANLTEEQYSDPRVGLIVGTGGASSSNQVQSADTLREKGVKRVGPYIVPRIMSSTASACLATPFKIKG
MNYSISSACATSAHCIGHAVELIQMGKQDMVFAGGAEEVDWTLTMGFDAMGALSTKYNATPEKASRTYDADRDGFVISGG
GGILVVEELEHALARGAKIYAEVIGYGASSDGYDMVAPSGEGAVRCMQMAMMDVDTPIDYINTHGTSTPVGDVRELEALR
EVFKDKCPPIASTKSMTGHALGAAGVHEAIYSLIMMENSFIAPSINIENLDDAAKDMPIVREYRDAELNTVMSNSFGFGG
TNATLVMRKFK

Sequences:

>Translated_411_residues
MYTMDSNKMKRVVITGMGVVSSIGNNKQEVTESLKAGRSGITHSAQFEEMQLRSHVWGDIKLNPAEHIDRKALRFMGDAA
AYAYIAMQEAVSDANLTEEQYSDPRVGLIVGTGGASSSNQVQSADTLREKGVKRVGPYIVPRIMSSTASACLATPFKIKG
MNYSISSACATSAHCIGHAVELIQMGKQDMVFAGGAEEVDWTLTMGFDAMGALSTKYNATPEKASRTYDADRDGFVISGG
GGILVVEELEHALARGAKIYAEVIGYGASSDGYDMVAPSGEGAVRCMQMAMMDVDTPIDYINTHGTSTPVGDVRELEALR
EVFKDKCPPIASTKSMTGHALGAAGVHEAIYSLIMMENSFIAPSINIENLDDAAKDMPIVREYRDAELNTVMSNSFGFGG
TNATLVMRKFK
>Mature_411_residues
MYTMDSNKMKRVVITGMGVVSSIGNNKQEVTESLKAGRSGITHSAQFEEMQLRSHVWGDIKLNPAEHIDRKALRFMGDAA
AYAYIAMQEAVSDANLTEEQYSDPRVGLIVGTGGASSSNQVQSADTLREKGVKRVGPYIVPRIMSSTASACLATPFKIKG
MNYSISSACATSAHCIGHAVELIQMGKQDMVFAGGAEEVDWTLTMGFDAMGALSTKYNATPEKASRTYDADRDGFVISGG
GGILVVEELEHALARGAKIYAEVIGYGASSDGYDMVAPSGEGAVRCMQMAMMDVDTPIDYINTHGTSTPVGDVRELEALR
EVFKDKCPPIASTKSMTGHALGAAGVHEAIYSLIMMENSFIAPSINIENLDDAAKDMPIVREYRDAELNTVMSNSFGFGG
TNATLVMRKFK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=422, Percent_Identity=35.0710900473934, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI223972627, Length=139, Percent_Identity=41.0071942446043, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI41872631, Length=338, Percent_Identity=26.6272189349112, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788663, Length=405, Percent_Identity=69.8765432098765, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=37.712895377129, Blast_Score=253, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=35.1674641148325, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=39.622641509434, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17550940, Length=356, Percent_Identity=26.4044943820225, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=356, Percent_Identity=26.685393258427, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=30.7349665924276, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24644341, Length=416, Percent_Identity=37.9807692307692, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI19920632, Length=338, Percent_Identity=27.2189349112426, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221330659, Length=338, Percent_Identity=27.2189349112426, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24581345, Length=345, Percent_Identity=22.3188405797101, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 44117; Mature: 44117

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTMDSNKMKRVVITGMGVVSSIGNNKQEVTESLKAGRSGITHSAQFEEMQLRSHVWGDI
CCCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
KLNPAEHIDRKALRFMGDAAAYAYIAMQEAVSDANLTEEQYSDPRVGLIVGTGGASSSNQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCCC
VQSADTLREKGVKRVGPYIVPRIMSSTASACLATPFKIKGMNYSISSACATSAHCIGHAV
HHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH
ELIQMGKQDMVFAGGAEEVDWTLTMGFDAMGALSTKYNATPEKASRTYDADRDGFVISGG
HHHHCCCCCEEEECCCCCEEEEEEECCCHHHHCCCCCCCCHHHHHCCCCCCCCCEEEECC
GGILVVEELEHALARGAKIYAEVIGYGASSDGYDMVAPSGEGAVRCMQMAMMDVDTPIDY
CCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHH
INTHGTSTPVGDVRELEALREVFKDKCPPIASTKSMTGHALGAAGVHEAIYSLIMMENSF
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHCCCC
IAPSINIENLDDAAKDMPIVREYRDAELNTVMSNSFGFGGTNATLVMRKFK
CCCCCCCCCCCHHHHCCCHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MYTMDSNKMKRVVITGMGVVSSIGNNKQEVTESLKAGRSGITHSAQFEEMQLRSHVWGDI
CCCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
KLNPAEHIDRKALRFMGDAAAYAYIAMQEAVSDANLTEEQYSDPRVGLIVGTGGASSSNQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCCC
VQSADTLREKGVKRVGPYIVPRIMSSTASACLATPFKIKGMNYSISSACATSAHCIGHAV
HHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH
ELIQMGKQDMVFAGGAEEVDWTLTMGFDAMGALSTKYNATPEKASRTYDADRDGFVISGG
HHHHCCCCCEEEECCCCCEEEEEEECCCHHHHCCCCCCCCHHHHHCCCCCCCCCEEEECC
GGILVVEELEHALARGAKIYAEVIGYGASSDGYDMVAPSGEGAVRCMQMAMMDVDTPIDY
CCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHH
INTHGTSTPVGDVRELEALREVFKDKCPPIASTKSMTGHALGAAGVHEAIYSLIMMENSF
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHCCCC
IAPSINIENLDDAAKDMPIVREYRDAELNTVMSNSFGFGGTNATLVMRKFK
CCCCCCCCCCCHHHHCCCHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]