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The map label for this gene is fabH2 [H]

Identifier: 160875859

GI number: 160875859

Start: 3267384

End: 3268451

Strand: Direct

Name: fabH2 [H]

Synonym: Sbal195_2748

Alternate gene names: 160875859

Gene position: 3267384-3268451 (Clockwise)

Preceding gene: 160875858

Following gene: 160875872

Centisome position: 61.1

GC content: 48.5

Gene sequence:

>1068_bases
ATGCAGTACGCCACTATCACAGGTTGGGGCAAATGTGTTCCACCAGCCACTCTGACCAACGATGATCTTGCGACCTTTAT
CGAGACATCCGACGAATGGATTAAATCTCGCACCGGCATCAGCCAGCGCCATATCAGTCATGTTAACACCTCTGAACTCG
CTTCAGTTGCAGCACAACGCGCGCTCGCAGCTGCGGGTATCGATGGCAGTGAAATCGACATGATCATTCTGGCTAGCGCC
AGCCCAGACACTTTGATCCCGAATATCGCATCAACTGTACAAGCTAATATTGGCGCCAGTTGTGCCGCGTTCGACATCAA
TGCTGCCTGCAGTGGCTTTTTATATGGCTTAGGTTTAGCCAGCTCACAAATCAAGAGTGGTCAGAGCAAGAAAGTATTGG
TGATTGGTGCCGAGCGTCTCTCTTTCTATTTAGATTGGTCACGCCGCGAAACTGCCGTGTTATTCGGTGATGGCGCTGGT
GCCGTTGTCGTTGAAGCAACAGATGTTGCCGGTGGCGTGCTTGGTTATGAACTGAATAACGATCCTGAAGGTCGTGACAT
TCTTAAAGCGGGCTTTGGCACGGCGATGGACAGATTCTCTGCCGAGTCATTGGATTTCTTTATTGAATTCGATGGCCAAG
AAATCTTCAAACGCGCGATTAACGGCATGAACAAGTTAAGCACTAAAGTGCTTGAAAAATGTGGCGTTGATAAAGATGAA
GTGGATCTAGTGATCCCGCATCAAGCCAACGAGCGCATTATCGATACCTTAGTCAGTCGGATGAAAATTCCGAAAGAAAA
AGCCTTCGTTAACATTGCCAATTATGGCAATACCTCGGCAGCAACCATTCCAATTGCGATTTGTGATGCGTTAGAGCAAG
GCGTGATCAAGCCGAATCAAACCATACTCTCTTGTGCCTTTGGTGCGGGCTTAACCTCTGCCGCACTCTTGCTGCAATGG
GGCGATCGCGTGACGCCTATCAATATCAGTGATGCCGAGTTACCGCCTTGCGATAAAACGGGCATAGAGTTAGTTAAACG
CGCTGTGGATTATTTTTGTAAGCCGTAA

Upstream 100 bases:

>100_bases
GTGGTCTAGATCACGGACGGCCATTAGAGTTGCCGATAAGCTTTGTTGTCGATTCAAGGCAGCGCTCAGGTTCTGCCTTT
TTTATTTGAGAGAAACCACC

Downstream 100 bases:

>100_bases
ACGGTTTCTGCAAAACGATAATATCGTGTTTTACTAAAACAAAAAGCCATCTTAATCGATGGCTTTTTTAGTTTATGACG
ACAGATCTTATTCATTCAGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAQRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQSKKVLVIGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVAGGVLGYELNNDPEGRDILKAGFGTAMDRFSAESLDFFIEFDGQEIFKRAINGMNKLSTKVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEQGVIKPNQTILSCAFGAGLTSAALLLQW
GDRVTPINISDAELPPCDKTGIELVKRAVDYFCKP

Sequences:

>Translated_355_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAQRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQSKKVLVIGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVAGGVLGYELNNDPEGRDILKAGFGTAMDRFSAESLDFFIEFDGQEIFKRAINGMNKLSTKVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEQGVIKPNQTILSCAFGAGLTSAALLLQW
GDRVTPINISDAELPPCDKTGIELVKRAVDYFCKP
>Mature_355_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAQRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQSKKVLVIGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVAGGVLGYELNNDPEGRDILKAGFGTAMDRFSAESLDFFIEFDGQEIFKRAINGMNKLSTKVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEQGVIKPNQTILSCAFGAGLTSAALLLQW
GDRVTPINISDAELPPCDKTGIELVKRAVDYFCKP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=36.1370716510903, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37813; Mature: 37813

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAQR
CCEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ALAAAGIDGSEIDMIILASASPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLA
HHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCC
SSQIKSGQSKKVLVIGAERLSFYLDWSRRETAVLFGDGAGAVVVEATDVAGGVLGYELNN
HHHHCCCCCCEEEEEEHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCC
DPEGRDILKAGFGTAMDRFSAESLDFFIEFDGQEIFKRAINGMNKLSTKVLEKCGVDKDE
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEQGVIKPNQ
EEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCC
TILSCAFGAGLTSAALLLQWGDRVTPINISDAELPPCDKTGIELVKRAVDYFCKP
CEEEEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAQR
CCEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ALAAAGIDGSEIDMIILASASPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLA
HHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCC
SSQIKSGQSKKVLVIGAERLSFYLDWSRRETAVLFGDGAGAVVVEATDVAGGVLGYELNN
HHHHCCCCCCEEEEEEHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCC
DPEGRDILKAGFGTAMDRFSAESLDFFIEFDGQEIFKRAINGMNKLSTKVLEKCGVDKDE
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEQGVIKPNQ
EEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCC
TILSCAFGAGLTSAALLLQWGDRVTPINISDAELPPCDKTGIELVKRAVDYFCKP
CEEEEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]