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The map label for this gene is gmhB [H]

Identifier: 160875857

GI number: 160875857

Start: 3265604

End: 3266152

Strand: Reverse

Name: gmhB [H]

Synonym: Sbal195_2746

Alternate gene names: 160875857

Gene position: 3266152-3265604 (Counterclockwise)

Preceding gene: 160875860

Following gene: 160875854

Centisome position: 61.08

GC content: 46.45

Gene sequence:

>549_bases
GTGAGTCGAGCAGTATTTTTAGACCGTGATGGCGTGATTAACAAAGATCATGGTTATGTCCACTTAGTGGATGACTTCGA
ATATATCGAAGGTGTGTTTGAATCTTGCCTCTCTTTGAAGGACATGGGCTACAAGTTAGTTGTCGTCACTAATCAATCTG
GTATTGCCCGTGGTATGTATACAGAAGATCAATTCCACAGCTTAACTGAGTGGATGGATTGGAACTTTGCCGACAAAGGC
GTTGAACTCGATGGTATCTACTATTGCCCGCACCATGCTGAAAATGGCATAGGGGAATATAAGGTCGACTGTGATTGCCG
CAAACCTAAGCCGGGTATGCTCAATGATGCGGCGCAATTCCTGAAAATAGACTTAGCTCTCTCAGTCATGGTTGGCGACA
AAGCCGAAGATATGCAGGCAGCGAAAGCGGCGGGCGTAACCACACGTATATTAGTGCGCACTGGTAAGGTTATTGCTGAT
GACAGTGATGCCACAGTGGTACTTGGCAGTATTGCCGATGTGCCGGCTTACTTAAAAAGCCTAGGCTAG

Upstream 100 bases:

>100_bases
ACGCTCAATTTAGCGTTAAAAGCACAACTTCGCGGTGCAATTTCTGATAATGAATGGAATAATAGCGCGATAACGCCTTA
GGCGATTTTGGAGTATTACA

Downstream 100 bases:

>100_bases
TTGCTGCACTACTACTTATAAGCAGATAAACATTTGCTGATAAGTTCATCTCAAGCAGCAACTATCACAGTAACCAGTAG
CGCGAGTTGCCGCTCTTGTT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKDMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKG
VELDGIYYCPHHAENGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLALSVMVGDKAEDMQAAKAAGVTTRILVRTGKVIAD
DSDATVVLGSIADVPAYLKSLG

Sequences:

>Translated_182_residues
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKDMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKG
VELDGIYYCPHHAENGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLALSVMVGDKAEDMQAAKAAGVTTRILVRTGKVIAD
DSDATVVLGSIADVPAYLKSLG
>Mature_181_residues
SRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKDMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKGV
ELDGIYYCPHHAENGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLALSVMVGDKAEDMQAAKAAGVTTRILVRTGKVIADD
SDATVVLGSIADVPAYLKSLG

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=178, Percent_Identity=61.2359550561798, Blast_Score=231, Evalue=2e-62,
Organism=Escherichia coli, GI87082027, Length=149, Percent_Identity=32.2147651006711, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20048; Mature: 19917

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKDMGYKLVVVTNQSGIARGMY
CCCEEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TEDQFHSLTEWMDWNFADKGVELDGIYYCPHHAENGIGEYKVDCDCRKPKPGMLNDAAQF
CCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHH
LKIDLALSVMVGDKAEDMQAAKAAGVTTRILVRTGKVIADDSDATVVLGSIADVPAYLKS
HHHEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCEEEEECHHHHHHHHHH
LG
CC
>Mature Secondary Structure 
SRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKDMGYKLVVVTNQSGIARGMY
CCEEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TEDQFHSLTEWMDWNFADKGVELDGIYYCPHHAENGIGEYKVDCDCRKPKPGMLNDAAQF
CCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHH
LKIDLALSVMVGDKAEDMQAAKAAGVTTRILVRTGKVIADDSDATVVLGSIADVPAYLKS
HHHEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCEEEEECHHHHHHHHHH
LG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]