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The map label for this gene is ggt [H]

Identifier: 160875845

GI number: 160875845

Start: 3240147

End: 3241886

Strand: Direct

Name: ggt [H]

Synonym: Sbal195_2733

Alternate gene names: 160875845

Gene position: 3240147-3241886 (Clockwise)

Preceding gene: 160875843

Following gene: 160875850

Centisome position: 60.59

GC content: 50.86

Gene sequence:

>1740_bases
ATGCGTCCAACAAGACCTTTTAGACCTCTTATTCTCGCCATTGCCATGGCGCTTCCCCTACTATCATCACCCAGTCTGCT
TGCCGAAGAATCGTCAATTTTCAGCCAGATGGCTACAGCACAACCTGTGTGGGCCAAGCATGGCATGGTTGCCAGCCAAG
AAACACTCGCCAGTCGCACCGGCGTTGAGATCCTAAAACAAGGGGGCAATGCCGTTGATGCGGCCGTGGCCGTGGCTTTT
AGTTTGGCAGTTACCTTACCACGTGCCGGCAATATCGGTGGCGGCGGTTTTATGTTGGTACATATTGCCAAAGAAAACAA
AACCATAGCAATCGATTACCGTGAAATGGCGCCATCTAAAGCCAAGAAAGATATTTTCCTCGACGAGAATGGCGATGCAG
TTGAGAAGCTGAGCCGCGAACACGGCCTTGCTGTAGGTGTCCCAGGTACAGTCATGGGCATGAGCTTAGCCCTTGAAAAA
TATGGCACTATGACACTCGCACAAGTCACTGCTCCTGCAATTAAAATGGCGCAGGAAGGCATTAGCGTGACGCCAGATCT
TGCCCAATCCCTTGCAGGTCTAAAACGCCGCATGACCCAATGGCCAACCACAGCCGCTATCTTCTACAAAGCCGACGGCA
GTGACTATCAAGTTGATGATATTCTTAAACAACCTGAGCTTGCCCATTCATTAAGTCTGATCGCTGAAAAAGGCACCAAA
GGATTCTACGAAGGTGAAACCGCCACTAAACTCATCAATGCGGTGAAAGACGCTGGCGGCATTATGACCTTAGACGACCT
TAAAAATTATAAGGTTGTAGAACGCGAACCCGTGCGCGGCGAATACCGTGGCTACGAGGTCGTGTCTATGCCACCACCAT
CATCGGGCGGCGTGCACATCATAGAAATGCTTAATGTGTTGCAACAATTCCCGATTGATAAACTCGGCCACAATACGGCG
CAGACGATTCATTTGATGGCAGAAACCATGAAGCATGCCTATAGCGATCGCAGCGAATACTTAGGCGATCCCGACTTTTA
TAAGGTGCCCGTCAAAGCCTTAACCAGTAAGGACTACGCCCAAAAAATCGCCAGCCAAATCGCGATGAATAAAACAACGC
CAAGCGCCGAAATCAAGCCAGGTAAACTCGCGCCCTATGAGAGCGACCAAACCACTCACTTCTCGGTAGTGGATAAATGG
GGCAATGCGGTTTCAAACACTTACACCTTAAACTTCAGCTACGGCTCAGGTTTAGTGGCCAAGGGTACTGGCATTTTGCT
CAATAACGAGATGGATGATTTCTCGGCCAAACCCGGCGTGCCAAACGGCTACGGTTTAGTTGGCGGTGATGCCAATGCGG
TCGAAGGCAATAAGCGCCCATTGAGCTCCATGAGCCCCACTATTGTGATGAAAGATGGCAAGCCCTTCCTCGTCACTGGC
AGCCCCGGCGGTTCACGCATTATCACCACCACACTGCAGATCATCATGAATGTGATCGACCATGGATTAAACATCGCCGA
AGCCAGTAATGCGGCGCGGGTACACCATCAATGGCTGCCCGATGAACTGCGAGTCGAATCCAGCTTAAACCGCGATACCA
TTTCCCTGCTCGAAGCCAAAGGCCACAAAGTGAAAGTACAGTCCGCTATGGGCAGCACACAATCAATCATGGTGACTGAA
CAAGGGATTTTTGGCGCGTCTGACCCGCGCCACTCAGGTAGCGAAGCCATCGGCTACTAG

Upstream 100 bases:

>100_bases
TTCTCGTCCTTTACGGATCTTAACTAATATACAAGGTTGCAATTAAGCCTAATTCTCGGCACATTGCATAGCCATAATGA
AAATAAATTCAGGATTGAGT

Downstream 100 bases:

>100_bases
CATCTCCATGATGCCAATGTTAGTGAAAGAGATGAATGTAAAGAGATGAGTGAGAGATAAGTAAGAGAAATAGGTGAATG
AGATAAAAGGATTTATGACC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MRPTRPFRPLILAIAMALPLLSSPSLLAEESSIFSQMATAQPVWAKHGMVASQETLASRTGVEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHIAKENKTIAIDYREMAPSKAKKDIFLDENGDAVEKLSREHGLAVGVPGTVMGMSLALEK
YGTMTLAQVTAPAIKMAQEGISVTPDLAQSLAGLKRRMTQWPTTAAIFYKADGSDYQVDDILKQPELAHSLSLIAEKGTK
GFYEGETATKLINAVKDAGGIMTLDDLKNYKVVEREPVRGEYRGYEVVSMPPPSSGGVHIIEMLNVLQQFPIDKLGHNTA
QTIHLMAETMKHAYSDRSEYLGDPDFYKVPVKALTSKDYAQKIASQIAMNKTTPSAEIKPGKLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGVPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTE
QGIFGASDPRHSGSEAIGY

Sequences:

>Translated_579_residues
MRPTRPFRPLILAIAMALPLLSSPSLLAEESSIFSQMATAQPVWAKHGMVASQETLASRTGVEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHIAKENKTIAIDYREMAPSKAKKDIFLDENGDAVEKLSREHGLAVGVPGTVMGMSLALEK
YGTMTLAQVTAPAIKMAQEGISVTPDLAQSLAGLKRRMTQWPTTAAIFYKADGSDYQVDDILKQPELAHSLSLIAEKGTK
GFYEGETATKLINAVKDAGGIMTLDDLKNYKVVEREPVRGEYRGYEVVSMPPPSSGGVHIIEMLNVLQQFPIDKLGHNTA
QTIHLMAETMKHAYSDRSEYLGDPDFYKVPVKALTSKDYAQKIASQIAMNKTTPSAEIKPGKLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGVPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTE
QGIFGASDPRHSGSEAIGY
>Mature_579_residues
MRPTRPFRPLILAIAMALPLLSSPSLLAEESSIFSQMATAQPVWAKHGMVASQETLASRTGVEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHIAKENKTIAIDYREMAPSKAKKDIFLDENGDAVEKLSREHGLAVGVPGTVMGMSLALEK
YGTMTLAQVTAPAIKMAQEGISVTPDLAQSLAGLKRRMTQWPTTAAIFYKADGSDYQVDDILKQPELAHSLSLIAEKGTK
GFYEGETATKLINAVKDAGGIMTLDDLKNYKVVEREPVRGEYRGYEVVSMPPPSSGGVHIIEMLNVLQQFPIDKLGHNTA
QTIHLMAETMKHAYSDRSEYLGDPDFYKVPVKALTSKDYAQKIASQIAMNKTTPSAEIKPGKLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGVPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTE
QGIFGASDPRHSGSEAIGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=538, Percent_Identity=32.5278810408922, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI73915090, Length=538, Percent_Identity=32.5278810408922, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI73915096, Length=538, Percent_Identity=32.5278810408922, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI73915094, Length=538, Percent_Identity=32.5278810408922, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI113429324, Length=528, Percent_Identity=32.1969696969697, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI113429326, Length=532, Percent_Identity=31.5789473684211, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI109148539, Length=551, Percent_Identity=31.0344827586207, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI153266901, Length=550, Percent_Identity=26.9090909090909, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI153266885, Length=548, Percent_Identity=26.8248175182482, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI153266907, Length=548, Percent_Identity=25.7299270072993, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI30581157, Length=229, Percent_Identity=36.6812227074236, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI30581155, Length=229, Percent_Identity=36.6812227074236, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI218505805, Length=228, Percent_Identity=34.6491228070175, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI310124095, Length=228, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1789856, Length=541, Percent_Identity=60.0739371534196, Blast_Score=642, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72000294, Length=574, Percent_Identity=31.7073170731707, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI212646519, Length=574, Percent_Identity=31.7073170731707, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17506189, Length=535, Percent_Identity=31.214953271028, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17542894, Length=556, Percent_Identity=32.0143884892086, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193208247, Length=508, Percent_Identity=30.3149606299213, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193208245, Length=508, Percent_Identity=30.3149606299213, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17564448, Length=423, Percent_Identity=28.6052009456265, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001497, Length=241, Percent_Identity=24.4813278008299, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72001495, Length=241, Percent_Identity=24.4813278008299, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323330, Length=529, Percent_Identity=30.2457466918715, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45551474, Length=545, Percent_Identity=31.743119266055, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI18859893, Length=531, Percent_Identity=32.5800376647834, Blast_Score=235, Evalue=7e-62,
Organism=Drosophila melanogaster, GI161077878, Length=545, Percent_Identity=31.743119266055, Blast_Score=235, Evalue=7e-62,
Organism=Drosophila melanogaster, GI161077880, Length=545, Percent_Identity=31.743119266055, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24642670, Length=545, Percent_Identity=31.743119266055, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24642666, Length=545, Percent_Identity=31.743119266055, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI161077496, Length=506, Percent_Identity=31.8181818181818, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI18859741, Length=546, Percent_Identity=29.1208791208791, Blast_Score=197, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62075; Mature: 62075

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTRPFRPLILAIAMALPLLSSPSLLAEESSIFSQMATAQPVWAKHGMVASQETLASRT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
GVEILKQGGNAVDAAVAVAFSLAVTLPRAGNIGGGGFMLVHIAKENKTIAIDYREMAPSK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCC
AKKDIFLDENGDAVEKLSREHGLAVGVPGTVMGMSLALEKYGTMTLAQVTAPAIKMAQEG
CCCCEEECCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHCC
ISVTPDLAQSLAGLKRRMTQWPTTAAIFYKADGSDYQVDDILKQPELAHSLSLIAEKGTK
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
GFYEGETATKLINAVKDAGGIMTLDDLKNYKVVEREPVRGEYRGYEVVSMPPPSSGGVHI
CCCCCHHHHHHHHHHHHCCCEEEHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHH
IEMLNVLQQFPIDKLGHNTAQTIHLMAETMKHAYSDRSEYLGDPDFYKVPVKALTSKDYA
HHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCHHHHCCHHHH
QKIASQIAMNKTTPSAEIKPGKLAPYESDQTTHFSVVDKWGNAVSNTYTLNFSYGSGLVA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCCEEE
KGTGILLNNEMDDFSAKPGVPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
CCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEC
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAK
CCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHCC
GHKVKVQSAMGSTQSIMVTEQGIFGASDPRHSGSEAIGY
CCEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPTRPFRPLILAIAMALPLLSSPSLLAEESSIFSQMATAQPVWAKHGMVASQETLASRT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
GVEILKQGGNAVDAAVAVAFSLAVTLPRAGNIGGGGFMLVHIAKENKTIAIDYREMAPSK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCC
AKKDIFLDENGDAVEKLSREHGLAVGVPGTVMGMSLALEKYGTMTLAQVTAPAIKMAQEG
CCCCEEECCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHCC
ISVTPDLAQSLAGLKRRMTQWPTTAAIFYKADGSDYQVDDILKQPELAHSLSLIAEKGTK
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
GFYEGETATKLINAVKDAGGIMTLDDLKNYKVVEREPVRGEYRGYEVVSMPPPSSGGVHI
CCCCCHHHHHHHHHHHHCCCEEEHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHH
IEMLNVLQQFPIDKLGHNTAQTIHLMAETMKHAYSDRSEYLGDPDFYKVPVKALTSKDYA
HHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCHHHHCCHHHH
QKIASQIAMNKTTPSAEIKPGKLAPYESDQTTHFSVVDKWGNAVSNTYTLNFSYGSGLVA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCCEEE
KGTGILLNNEMDDFSAKPGVPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
CCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEC
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAK
CCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHCC
GHKVKVQSAMGSTQSIMVTEQGIFGASDPRHSGSEAIGY
CCEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]