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The map label for this gene is sdhB [H]

Identifier: 160875741

GI number: 160875741

Start: 3115377

End: 3116084

Strand: Reverse

Name: sdhB [H]

Synonym: Sbal195_2629

Alternate gene names: 160875741

Gene position: 3116084-3115377 (Counterclockwise)

Preceding gene: 160875742

Following gene: 160875740

Centisome position: 58.27

GC content: 44.63

Gene sequence:

>708_bases
ATGAAATTGACATTTGCAGTTTATCGCTACAATCCTGACGTAGATACTAAACCGTATATGCAGGATTACACCTTAGAAGT
GGCTGAAGGCTCTGACATGATGGTGCTCGATGCACTGATCAAGTTAAAAGAGCAAGATCCGACTCTGTCATTCCGTCGCT
CATGCCGTGAAGGTGTGTGTGGTTCTGACGGCGTGAACATGAATGGTAAAAATGGTCTGGCGTGTATTACCCCAATTTCA
ACCTTTAAAGGCAAGAAATTAGAAATACGTCCATTACCAGGTATGCCAGTTGTTCGCGACTTAGTCGTTGATTTAACTCA
GTTCTATAAGCAGTATGAGAAGATCAAGCCTTACCTCATCAATGATGAGAAAGCACCAGCCCGTGAACACTTACAATCAC
CTGAAGAGCGTGCTCATTTAGATGGTCTGTACGAATGTATCATGTGTGCCTGTTGTTCTACGGCTTGCCCATCATTCTGG
TGGAATCCTGATAAGTTTATCGGTCCAAGCGGTCTGCTTCACGCATATCGTTTCTTGATCGACAGTCGCGATACAGCAAC
AGAAGAACGTTTATCTGAGCTGGACGACGCCTATAGCGTGTTCCGTTGCCACGGCATCATGAACTGCGTTGACGTTTGTC
CAAAAGGTCTTAATCCGACTAAAGCAATTGGTCATATTAAGTCCATGCTGTTGAAGCGAGCAGTGTAA

Upstream 100 bases:

>100_bases
ACCCAATCACTGAAACGATGGATCGTCGTGCAGTGAACATGGCACCTAAGTTACGTGAAGCATTCCCGCCGAAGAAACGT
ACCTACTAGGAGTTGCAAAG

Downstream 100 bases:

>100_bases
TGCGAGAACCCGAGCTGAAACCAATAATAATATAGCTCTTGAAGAGTCACTTTCTGGTAGCAGAAGGTGACTCTTTTGCG
TATGTAATGGAAGACAACGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKLTFAVYRYNPDVDTKPYMQDYTLEVAEGSDMMVLDALIKLKEQDPTLSFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPYLINDEKAPAREHLQSPEERAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV

Sequences:

>Translated_235_residues
MKLTFAVYRYNPDVDTKPYMQDYTLEVAEGSDMMVLDALIKLKEQDPTLSFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPYLINDEKAPAREHLQSPEERAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
>Mature_235_residues
MKLTFAVYRYNPDVDTKPYMQDYTLEVAEGSDMMVLDALIKLKEQDPTLSFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPYLINDEKAPAREHLQSPEERAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=230, Percent_Identity=56.9565217391304, Blast_Score=270, Evalue=1e-72,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=77.9661016949153, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1790596, Length=228, Percent_Identity=39.0350877192982, Blast_Score=154, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17533915, Length=233, Percent_Identity=53.2188841201717, Blast_Score=256, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=55.6521739130435, Blast_Score=262, Evalue=3e-71,
Organism=Drosophila melanogaster, GI17137106, Length=232, Percent_Identity=56.4655172413793, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=52.5862068965517, Blast_Score=256, Evalue=1e-68,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26571; Mature: 26571

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTFAVYRYNPDVDTKPYMQDYTLEVAEGSDMMVLDALIKLKEQDPTLSFRRSCREGVC
CCEEEEEEEECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGVNMNGKNGLACITPISTFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPYLI
CCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
NDEKAPAREHLQSPEERAHLDGLYECIMCACCSTACPSFWWNPDKFIGPSGLLHAYRFLI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLTFAVYRYNPDVDTKPYMQDYTLEVAEGSDMMVLDALIKLKEQDPTLSFRRSCREGVC
CCEEEEEEEECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGVNMNGKNGLACITPISTFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPYLI
CCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
NDEKAPAREHLQSPEERAHLDGLYECIMCACCSTACPSFWWNPDKFIGPSGLLHAYRFLI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]