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The map label for this gene is ribE [H]

Identifier: 160875445

GI number: 160875445

Start: 2750806

End: 2751429

Strand: Reverse

Name: ribE [H]

Synonym: Sbal195_2333

Alternate gene names: 160875445

Gene position: 2751429-2750806 (Counterclockwise)

Preceding gene: 160875447

Following gene: 160875442

Centisome position: 51.45

GC content: 44.23

Gene sequence:

>624_bases
ATGTTTACAGGTATAGTTCAAGCCACCTGCGAGGTGGTTGCAATACATAAGAAAGATGGCCTAAATACCCTTGAGGTAGC
GTTCGAACCTGATTTGCATGAGGGACTTGCGATTGGTGCAAGTGTGGCAAATAACGGGGTATGTCTTACTGTGACTCAGG
TCGTTGATGATAGGGTATTTTTCGACGTAGTGGAAGAGACCTTGCGACTGACGAATCTGGCTAATTTGTCTATAGGTCAA
AGCGTTAATGTTGAGCGTTCGTTAACTTTTGGTAGTGAGATTGGTGGTCACATTCTCTCTGGCCATATCCATACTAAGGC
TAAAGTCGTTGATATTAGCCATACAGAACAGCATTATGATCTGACACTGGGCATTGAGCCTAAATGGATGGATTACATTT
TTTATAAAGGTTTTGTTGGCGTTAACGGCTGCAGCTTAACGGTAGGCGAGGTGAGTGACTCCGGCTTTAAGTTGCACTTA
ATTCCTGAAACCCTAAAACTGACCAATTTAAGTCAGTATAAAGTGGGTGATGAACTCAATATTGAGATCGACAGCCAAAC
GCAAGTTATCGTCGACACTGTCGAGCGCGTGCTGGCCAGGCGTTTTAACGAACAAGCCCGTTAG

Upstream 100 bases:

>100_bases
CCTGAGCTATTAGCACCGGCAGCGCCAATTGGATTAAACGTTTGGCTTGATAGCCTGAATTATTCATAAATACAGCCTTT
AACGATTAAGCGAGCAAAAA

Downstream 100 bases:

>100_bases
TTTCATGACATCGCAGCCTTTAATGCAATCTCGTTTAATAGATTTGCTCGTCGTCTGAATCGATATACAGCTCAACGATA
CGTCTCAATTCGTCGATATG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGIVQATCEVVAIHKKDGLNTLEVAFEPDLHEGLAIGASVANNGVCLTVTQVVDDRVFFDVVEETLRLTNLANLSIGQ
SVNVERSLTFGSEIGGHILSGHIHTKAKVVDISHTEQHYDLTLGIEPKWMDYIFYKGFVGVNGCSLTVGEVSDSGFKLHL
IPETLKLTNLSQYKVGDELNIEIDSQTQVIVDTVERVLARRFNEQAR

Sequences:

>Translated_207_residues
MFTGIVQATCEVVAIHKKDGLNTLEVAFEPDLHEGLAIGASVANNGVCLTVTQVVDDRVFFDVVEETLRLTNLANLSIGQ
SVNVERSLTFGSEIGGHILSGHIHTKAKVVDISHTEQHYDLTLGIEPKWMDYIFYKGFVGVNGCSLTVGEVSDSGFKLHL
IPETLKLTNLSQYKVGDELNIEIDSQTQVIVDTVERVLARRFNEQAR
>Mature_207_residues
MFTGIVQATCEVVAIHKKDGLNTLEVAFEPDLHEGLAIGASVANNGVCLTVTQVVDDRVFFDVVEETLRLTNLANLSIGQ
SVNVERSLTFGSEIGGHILSGHIHTKAKVVDISHTEQHYDLTLGIEPKWMDYIFYKGFVGVNGCSLTVGEVSDSGFKLHL
IPETLKLTNLSQYKVGDELNIEIDSQTQVIVDTVERVLARRFNEQAR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=51.9607843137255, Blast_Score=205, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6319733, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22784; Mature: 22784

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQATCEVVAIHKKDGLNTLEVAFEPDLHEGLAIGASVANNGVCLTVTQVVDDRVF
CCCCCEECEEEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEHHHHCCHHH
FDVVEETLRLTNLANLSIGQSVNVERSLTFGSEIGGHILSGHIHTKAKVVDISHTEQHYD
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECEEECEEEEEEECCCCCEEE
LTLGIEPKWMDYIFYKGFVGVNGCSLTVGEVSDSGFKLHLIPETLKLTNLSQYKVGDELN
EEEECCCHHHHEEEEECCCCCCCCEEEEECCCCCCEEEEEECCEEEECCCCCEECCCEEE
IEIDSQTQVIVDTVERVLARRFNEQAR
EEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVQATCEVVAIHKKDGLNTLEVAFEPDLHEGLAIGASVANNGVCLTVTQVVDDRVF
CCCCCEECEEEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEHHHHCCHHH
FDVVEETLRLTNLANLSIGQSVNVERSLTFGSEIGGHILSGHIHTKAKVVDISHTEQHYD
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECEEECEEEEEEECCCCCEEE
LTLGIEPKWMDYIFYKGFVGVNGCSLTVGEVSDSGFKLHLIPETLKLTNLSQYKVGDELN
EEEECCCHHHHEEEEECCCCCCCCEEEEECCCCCCEEEEEECCEEEECCCCCEECCCEEE
IEIDSQTQVIVDTVERVLARRFNEQAR
EEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]