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The map label for this gene is glnS [H]

Identifier: 160874736

GI number: 160874736

Start: 1956838

End: 1958508

Strand: Direct

Name: glnS [H]

Synonym: Sbal195_1619

Alternate gene names: 160874736

Gene position: 1956838-1958508 (Clockwise)

Preceding gene: 160874735

Following gene: 160874738

Centisome position: 36.59

GC content: 43.69

Gene sequence:

>1671_bases
ATGAGTCATGTGGACACTGAAGTACGTCCGAGTAACTTTATTCGTAATATCATAGATGAAGATTTACAAAGCGGTAAGCA
CACGAGTGTACAGACTCGTTTCCCGCCGGAACCGAATGGCTATCTTCATATTGGTCATGCTAAATCTATCTGCTTAAATT
TTGGGATAGCGCGAGACTATAACGGTCTGTGTAATTTACGTTTTGACGATACAAATCCTGAAAAAGAAGACATTGATTAT
GTGAATTCTATTCAGGCGGATGTGCGTTGGCTTGGATTCCAGTGGGATGGCGATGTACGCTATTCATCAAACTATTTTGA
TCAGTTACATCAATATGCAGTTGAACTGATCAATAAAGGTTTGGCTTATGTGTGTTTCTTGAATGCTGATGAAACTCGCG
AATACCGTGGCACGTTAAAAGAGCCAGGTAAAAACAGTCCTTTCCGCGACACATCAGTCGAAGAGAATCTTGCCTTATTC
GCTAAGATGCGCGACGGTGGTTTTAAAGAAGGTGAGTGTGCGCTGCGTGCCAAAATTGATATGGCGTCGCCATTCATGTG
TATGCGCGATCCTATCATCTATCGTATTCGTTTTGCCCATCACCACCAAACGGGTGACAAGTGGTGCATTTACCCAATGT
ACGACTTTACCCACTGTATTTCTGATGCGTTAGAACATATTACCCATTCTTTATGTACTTTAGAGTTCCAAGACAACCGT
CGTTTATACGACTGGGTGTTGGATAATTTGAATGATTTTCAAGCGCCGAATCGTACTCGTCAATACGAGTTTTCACGCTT
AAATCTCGAATATACCTTGATGTCTAAGCGTAAGCTAAACGATCTTGTGACCCGTAAATTAGTGTCAGGTTGGGACGACC
CACGTATGCCAACGATTGCTGGTCTACGTCGTCGTGGTTACACGCCTGCGTCAATTCGCGAGTTCTGCCAACGTATCGGC
GTGACTAAGCAAGAGAATATGATTGAAGTCGGCATGTTAGATGCGTGTATTCGTGAAGAATTGAACGAACATGCACCGCG
TGCTATGGCCGTATTACGTCCATTGAAACTGATCATCGAAAACTATGCTGAAGGTGAACTTGAGTACATTCAAGCGGCCG
CTCATCCAAATGATGAGAGCATGGGGACGCGTGAATTAGCCTTTGGCCGTGAAATATTGATTGATGTGGCTGACTTTAGA
GAAGAAGCCAACAAACAATACAAACGCCTTGTGACAGGCAAAGAAGTACGTTTACGCAATGCCTATGTGATTAAAGCTGA
GCGTTGTGACAAAGACAGCGAAGGCAATATTACGACGGTTTACTGCACTTATGATCCTGAAACCTTAGGTAAAAACCCTG
CTGATGGCCGTAAAGTCAAAGGCGTGATCCATTGGGTTGAGGCATCTACTGCCAAGCCTGCTGAATTCCGCTTATATCAG
CGTTTATTTACCGATCCTAATCCAGCTGCCGCTGAGACTGTGGACGAAGTATTAAACCCTGAATCATTAGTGGTTGTGTA
CGGTTTTGCTGAAGCAAGCCTAGTAAATGCACCAGCAGAAAAAGCTTATCAGTTTGAGCGTGAAGGTTATTTCTGTGCTG
ACAGCAAAGATTCATCAGCTGATAAACTCGTGTTTAACTTAACCGTAGCGCTGCGTGATTCTTTCGAATGA

Upstream 100 bases:

>100_bases
CAAAAACCATAGTTTTTAGCACTAGGCATTGTAACTAGTAGTGATCTGTAGGATCATGCTGGTTTTCTTAAAATTGCCAT
TGTTCGCAAAGAGGAATTCC

Downstream 100 bases:

>100_bases
TTTGATAGCATTGGTTTGATAGAATTTGTTTGATGAAATGAGTCAAACAGTTCAACTCAACGAAGCTAAGTTGAATTAAG
CTAAGTCATTCTGATCATTA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDY
VNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALF
AKMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKLIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFR
EEANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
RLFTDPNPAAAETVDEVLNPESLVVVYGFAEASLVNAPAEKAYQFEREGYFCADSKDSSADKLVFNLTVALRDSFE

Sequences:

>Translated_556_residues
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDY
VNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALF
AKMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKLIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFR
EEANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
RLFTDPNPAAAETVDEVLNPESLVVVYGFAEASLVNAPAEKAYQFEREGYFCADSKDSSADKLVFNLTVALRDSFE
>Mature_555_residues
SHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDYV
NSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFA
KMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNRR
LYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIGV
TKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKLIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFRE
EANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQR
LFTDPNPAAAETVDEVLNPESLVVVYGFAEASLVNAPAEKAYQFEREGYFCADSKDSSADKLVFNLTVALRDSFE

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=530, Percent_Identity=46.2264150943396, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=516, Percent_Identity=32.1705426356589, Blast_Score=257, Evalue=3e-68,
Organism=Escherichia coli, GI1786895, Length=551, Percent_Identity=74.0471869328494, Blast_Score=857, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=107, Percent_Identity=29.9065420560748, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=535, Percent_Identity=43.3644859813084, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17511007, Length=523, Percent_Identity=30.7839388145315, Blast_Score=223, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324742, Length=567, Percent_Identity=39.5061728395062, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321192, Length=530, Percent_Identity=33.3962264150943, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI17864488, Length=533, Percent_Identity=42.2138836772983, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=421, Percent_Identity=39.9049881235154, Blast_Score=270, Evalue=2e-72,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63966; Mature: 63835

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDY
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHCCCCCCCC
NGLCNLRFDDTNPEKEDIDYVNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKG
CCEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHCC
LAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFAKMRDGGFKEGECALRAKID
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKLIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
NYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFREEANKQYKRLVTGKEVRLRN
HCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
EEEEEEHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFTDPNPAAAETVDEVLNPESLVVVYGFAEASLVNAPAEKAYQFEREGYFCADSKDSSA
HHHCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCHHHHHHHHCCCEEEECCCCCCC
DKLVFNLTVALRDSFE
CEEEEEEEEEECCCCC
>Mature Secondary Structure 
SHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDY
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHCCCCCCCC
NGLCNLRFDDTNPEKEDIDYVNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKG
CCEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHCC
LAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFAKMRDGGFKEGECALRAKID
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKLIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
NYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFREEANKQYKRLVTGKEVRLRN
HCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
EEEEEEHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFTDPNPAAAETVDEVLNPESLVVVYGFAEASLVNAPAEKAYQFEREGYFCADSKDSSA
HHHCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCHHHHHHHHCCCEEEECCCCCCC
DKLVFNLTVALRDSFE
CEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]