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The map label for this gene is ddc [H]

Identifier: 160874720

GI number: 160874720

Start: 1931494

End: 1933143

Strand: Reverse

Name: ddc [H]

Synonym: Sbal195_1603

Alternate gene names: 160874720

Gene position: 1933143-1931494 (Counterclockwise)

Preceding gene: 160874721

Following gene: 160874718

Centisome position: 36.15

GC content: 51.09

Gene sequence:

>1650_bases
ATGACCCAGAAACTCCCTCGCCAAGCCACAGCATCCGAAGAAAGTCTGCTCCGCATTTTTACTGCACCGGAAGATGCAGG
ATCAACGCTGAGTATTATCGAGCAGAAGCTCTCCGAGGACTTAGCAGGCTTTTTGGGTGACAGTATCGCCGCGCTCGAAA
AACCCTTGTCGGAAATTGAAACCGATTTTCAAGCCTTTGAGATCCCAACTCAGCCGCGTTTCGTCTCCGATTACACCGAC
GAGATCATGCAAAATCTGGTGGCGCATTCGGTACACACAGCGGCACCAAGTTTTATCGGCCACATGACGTCGGCACTGCC
CTACTTTGTGTTGCCGCTGTCGAAAATGATGGTGGGACTGAATCAAAATCTGGTCAAAATCGAAACCTCAAAGGCATTTA
CGCCGCTTGAGCGCCAAGTGCTCGGCATGATGCACCATTTGATTTACGACCAAGATACGGATTTTTATCAAAGCTGGATG
CACAGTGCGAATCATTCCCTCGGGGCATTTTGCTCCGGCGGCACAGTGGCCAACATCACCGCCCTGTGGATTGCCCGCAA
CCAATTATTGAAAGCCGATGGCGAGTTTAAAGGCGTCAGCCGCGAAGGTTTACTCAAGGCACTGCGCCACTATGGCTATG
ACGATTTAGCGATTTTAGTCTCGGAGCGCGGTCACTATTCGCTAGGCAAAGCCGTCGATCTGCTTGGTATCGGTCGTGAC
AATATCATCAGCATTCCCACGGGCATCGATAACAAGGTCGATGTCGCGAAAATGCGCCAAGCCGCCCTTGAACTTGCCAG
TAAAAACATCAAAGTGTTGGCGATTGTTGGTGTGGCTGGCACCACAGAAACCGGTAATGTTGACCCATTGACAGAATTAG
CGGCGCTGGCAAAAGAGTTAAATTGCCATTTCCATGTGGATGCGGCGTGGGGAGGCGCGAGTTTATTATCCAATAAATAC
CGCCACTTACTCACAGGTATCGAACTTGCCGATTCAGTCACCATAGATGCCCACAAACAAATGTACGTGCCTATGGGCGC
GGGTATGGTGTTATTTAAAGACCCAGAGTTCGCCCACGCCATTGCCCATCACGCCGAATATATTCTGCGCCGTGGTTCAA
AGGACTTAGGCAGCCAAACGCTCGAAGGTTCACGCCCCGGCATGGCGATGTTAGTGCACGCTTGCTTACAGATCATCGGC
CGCGATGGGTATGAAATCTTAATCAATAACAGCCTTGAAAAAGCGCGTTATTTTGCCGAGCAAATCAAAGCCCATAAGGA
TTTTGAGCTGGTCACTGAGCCAGAACTGTGTCTGCTGACTTATCGTTATGTCCCCGCCTGCGTCCAAGCCGCCATACAGC
TTGCCTGTGAGCAAGCAGACACGATAAGAGTCGCCCGCTTTAACGAGCTGCTCGATGGCCTGACACAGTTTATTCAAAAG
CACCAACGCGAACAGGGTAAATCCTTCGTCTCCCGCACCCGCATTCAGCCAGCCCGCTACTTTAGGCAAGCGACCGTGGT
GTTTCGCGTAGTGCTCGCTAACCCCCTCACCAGCCATGACATCCTCAATCAAGTGCTTGTTGAGCAAAGTGAAATCGCCG
CACTAGATAATGAGTTTTTACCCGTACTCATGGCGATGGTTGCTGATTAG

Upstream 100 bases:

>100_bases
ATTGAACATTTTGAGAGTCGCTGGTCGAAAGTCACTGGTCCGTTATACTCTTCGAGCAAATTTGCGGTTTCACTATAAAA
ATTAATAGACGGCAAGCCCC

Downstream 100 bases:

>100_bases
CAAGTGGTTTGATGTAAGCTTTCAATCCCAGTTCAAATACAGTGTGTTAATCGCAAACAGCCGCAAATTTTTTGCGGCTG
TTTTTATTGGCAGAGCTAAA

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTGIDNKVDVAKMRQAALELASKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKY
RHLLTGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIKAHKDFELVTEPELCLLTYRYVPACVQAAIQLACEQADTIRVARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLVEQSEIAALDNEFLPVLMAMVAD

Sequences:

>Translated_549_residues
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTGIDNKVDVAKMRQAALELASKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKY
RHLLTGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIKAHKDFELVTEPELCLLTYRYVPACVQAAIQLACEQADTIRVARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLVEQSEIAALDNEFLPVLMAMVAD
>Mature_548_residues
TQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTDE
IMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMH
SANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRDN
IISIPTGIDNKVDVAKMRQAALELASKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKYR
HLLTGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGR
DGYEILINNSLEKARYFAEQIKAHKDFELVTEPELCLLTYRYVPACVQAAIQLACEQADTIRVARFNELLDGLTQFIQKH
QREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLVEQSEIAALDNEFLPVLMAMVAD

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=372, Percent_Identity=28.494623655914, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI197276620, Length=477, Percent_Identity=26.4150943396226, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4503875, Length=477, Percent_Identity=26.4150943396226, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI58331246, Length=390, Percent_Identity=28.7179487179487, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI194294551, Length=373, Percent_Identity=27.6139410187668, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4503281, Length=383, Percent_Identity=20.6266318537859, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI132814448, Length=383, Percent_Identity=20.6266318537859, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI31982936, Length=261, Percent_Identity=25.6704980842912, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555682, Length=476, Percent_Identity=25.4201680672269, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71993062, Length=460, Percent_Identity=25.6521739130435, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71993058, Length=375, Percent_Identity=27.2, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17543922, Length=284, Percent_Identity=26.056338028169, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17136594, Length=450, Percent_Identity=28.6666666666667, Blast_Score=152, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24657193, Length=367, Percent_Identity=26.7029972752044, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24657185, Length=367, Percent_Identity=26.7029972752044, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24657188, Length=367, Percent_Identity=26.7029972752044, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356415, Length=381, Percent_Identity=22.8346456692913, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24585139, Length=249, Percent_Identity=26.5060240963855, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221476190, Length=249, Percent_Identity=26.5060240963855, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24585143, Length=249, Percent_Identity=26.5060240963855, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24652373, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 60644; Mature: 60513

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPTQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
NIISIPTGIDNKVDVAKMRQAALELASKNIKVLAIVGVAGTTETGNVDPLTELAALAKEL
CEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLTGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEEECCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIKAHKDFELVTEPELCLLTYRYVPACVQAAIQLACEQADTIRVARFNELLDGLTQFIQK
HHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLVEQSEIAALDNEFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
PVLMAMVAD
HHHHHHHCC
>Mature Secondary Structure 
TQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPTQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
NIISIPTGIDNKVDVAKMRQAALELASKNIKVLAIVGVAGTTETGNVDPLTELAALAKEL
CEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLTGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEEECCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIKAHKDFELVTEPELCLLTYRYVPACVQAAIQLACEQADTIRVARFNELLDGLTQFIQK
HHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLVEQSEIAALDNEFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
PVLMAMVAD
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]