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The map label for this gene is crt [H]

Identifier: 160874645

GI number: 160874645

Start: 1840921

End: 1841694

Strand: Direct

Name: crt [H]

Synonym: Sbal195_1528

Alternate gene names: 160874645

Gene position: 1840921-1841694 (Clockwise)

Preceding gene: 160874644

Following gene: 160874646

Centisome position: 34.43

GC content: 50.9

Gene sequence:

>774_bases
ATGGAATATTTAGTAGAACGTATCGAAGGCCATACGGCCATTCTGACGATGAATAATCCACCGGCAAATACTTGGACCGC
CGAGAGTTTGCAGGCGCTCAAAGCCAAAGTGCTTGAGCTGAACGCGAATAAAGAAATTTATGCCTTAGTGTTAACGGGCC
AAGGGCAAAAGTTCTTCTCTGCCGGTGCCGATTTGAAGCTGTTTAGTGATGGCGACAAAGGCAATGCGGCGACGATGGCA
AAGCACTTCGGTGAAGCCTTTGAAACCCTAAGTCAATTCCGCGGTGTATCGATTGCCGCGATTAACGGTTATGCCATGGG
CGGCGGCTTAGAAGTCGCACTTGCCTGTGATATTCGAATCGCCGAAATTCAAGCTGTGATGGCATTGCCTGAAGCGACCG
TAGGTTTATTACCTTGCGCAGGTGGCACCCAGAATCTGACCGCATTAGTTGGTGAAGGTTGGGCTAAGCGGATGATTTTA
TGCGGTGAGCGCGTCGATGCGACTCAAGCTTTGAATCTGCGTTTAGTGGAAGAAGTGGTCGAAACGGGCGAAGCGCTCAA
TGCGGCAATTGCGTTGGCCGTAAAAGTCGCCAACCAAAGCCCAAGCAGCGTCACAGCGTGCAAGACACTCATTCAAGCGG
GCCGCACTATGGCGCGTAGCCAAGCGCTGCCGATTGAGCGTGAATTATTTGTCGGGTTATTTGATACCGAAGATCAGGCC
GAAGGCGTGAATGCGTTTTTGGGCAAACGTAAAGCTGATTGGAAGAACCGCTAA

Upstream 100 bases:

>100_bases
CCCGTCGTTTACTCGATGAAAATGCAGGACAAATCCTCTAAGTCTACTCGCAAGAAGTGTGACTTATCGGTTGGCGATAA
CATAAAAGGAGTCTATACAG

Downstream 100 bases:

>100_bases
TGACTAATGTAGTAGATAACGTAAATCAGGCCACGACCACGCAAAACGTGGTTTTTCAAACCTTAGCCACCGCGTCCGGT
AAGTTGATTGGGGTGGTGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MEYLVERIEGHTAILTMNNPPANTWTAESLQALKAKVLELNANKEIYALVLTGQGQKFFSAGADLKLFSDGDKGNAATMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVDATQALNLRLVEEVVETGEALNAAIALAVKVANQSPSSVTACKTLIQAGRTMARSQALPIERELFVGLFDTEDQA
EGVNAFLGKRKADWKNR

Sequences:

>Translated_257_residues
MEYLVERIEGHTAILTMNNPPANTWTAESLQALKAKVLELNANKEIYALVLTGQGQKFFSAGADLKLFSDGDKGNAATMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVDATQALNLRLVEEVVETGEALNAAIALAVKVANQSPSSVTACKTLIQAGRTMARSQALPIERELFVGLFDTEDQA
EGVNAFLGKRKADWKNR
>Mature_257_residues
MEYLVERIEGHTAILTMNNPPANTWTAESLQALKAKVLELNANKEIYALVLTGQGQKFFSAGADLKLFSDGDKGNAATMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVDATQALNLRLVEEVVETGEALNAAIALAVKVANQSPSSVTACKTLIQAGRTMARSQALPIERELFVGLFDTEDQA
EGVNAFLGKRKADWKNR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=265, Percent_Identity=34.7169811320755, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI68989263, Length=211, Percent_Identity=35.5450236966825, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=29.3859649122807, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=29.3859649122807, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=33.5195530726257, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4502327, Length=237, Percent_Identity=29.957805907173, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI157694520, Length=210, Percent_Identity=29.5238095238095, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI261878539, Length=113, Percent_Identity=42.4778761061947, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI31542718, Length=258, Percent_Identity=26.3565891472868, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150378541, Length=256, Percent_Identity=30.859375, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=27.0967741935484, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=27.0967741935484, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI62530384, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=39.3822393822394, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=32.3886639676113, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=37.2448979591837, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790281, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082183, Length=237, Percent_Identity=24.4725738396624, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=28.2442748091603, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=34.6456692913386, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=32.6612903225806, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17540714, Length=233, Percent_Identity=31.3304721030043, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17558304, Length=186, Percent_Identity=30.6451612903226, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25144160, Length=192, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25144157, Length=192, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=258, Percent_Identity=24.4186046511628, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=25.8687258687259, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=196, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=34.0909090909091, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=34.0909090909091, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=31.2977099236641, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24650670, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357171, Length=149, Percent_Identity=32.8859060402685, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583165, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=22.1343873517787, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921018, Length=172, Percent_Identity=27.3255813953488, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27370; Mature: 27370

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLVERIEGHTAILTMNNPPANTWTAESLQALKAKVLELNANKEIYALVLTGQGQKFFS
CHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEEECCCCHHHH
AGADLKLFSDGDKGNAATMAKHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEECEEH
AEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERVDATQALNLRLVEEVV
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHEEECCCCCHHHHHHHHHHHHHH
ETGEALNAAIALAVKVANQSPSSVTACKTLIQAGRTMARSQALPIERELFVGLFDTEDQA
HCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCHH
EGVNAFLGKRKADWKNR
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEYLVERIEGHTAILTMNNPPANTWTAESLQALKAKVLELNANKEIYALVLTGQGQKFFS
CHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEEECCCCHHHH
AGADLKLFSDGDKGNAATMAKHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEECEEH
AEIQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERVDATQALNLRLVEEVV
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHEEECCCCCHHHHHHHHHHHHHH
ETGEALNAAIALAVKVANQSPSSVTACKTLIQAGRTMARSQALPIERELFVGLFDTEDQA
HCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCHH
EGVNAFLGKRKADWKNR
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]