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The map label for this gene is cysQ [H]

Identifier: 160874622

GI number: 160874622

Start: 1815402

End: 1816208

Strand: Direct

Name: cysQ [H]

Synonym: Sbal195_1505

Alternate gene names: 160874622

Gene position: 1815402-1816208 (Clockwise)

Preceding gene: 160874621

Following gene: 160874623

Centisome position: 33.95

GC content: 49.57

Gene sequence:

>807_bases
GTGACAGACAAGACGACAATAGCGCAGACATTGACCAAACAAGATCTACTGCAAGTGGTCGCGATTGCCAAAGCCGCAGG
CGATGCCATTATGACGGTTTATGGTCAAGATGACTTTTCAGTGAGCCATAAGGGCGATGATAGTCCCGTGACAGCGGCCG
ATTTAGCCGCGCACCACGTGATAGTGGCGGCATTGGCAAAGCAGTTTGTCGGTATTCCTATTATGTCTGAGGAAGCGGCG
GATATTGCGTGGGATGAGCGTCGTCAATGGCAAACCTATTGGTTAATTGACCCTTTAGATGGCACTAAGGAATTTATTAA
GCGCAATGGTGAGTTTACCGTCAATATTGCGCTTATCCATCAAGGGGTTGCAATCGCAGGAGTGGTATATGCGCCTGTGC
TCGATACCTATTATTACGGCGCTAAGCATTTAGGTGCATGGCGTCAACAAGCGGGTCAAGAAAGTCCCTTATTGGGCGCT
AAAGCGCCACGCGCGATGCCGATGATTGTTGGCAGTCGCTCGCACTTGAGCCCTGGTTTAGCGCAATATTTACAACAGTT
TGGCGAGCATGACATCTTAAGCGTGGGGAGCTCGCTTAAGTTTTGTATGTTGGCAGAAGGCAGTGCCGATCTGTACCCCA
GACTTGGCCCAACTAGCGAATGGGATACTGCTGCGGCGCAAGCTGTGCTCGAAAGTGCTGGCGGCACAGTTGTCTGTTAC
GACTCAGGTGAACCATTAACTTATAATCAAAAACCTGACATTTTAAACCCTTACTTTATTGCCACAGCCCCAGGCTGGGT
GAAATAA

Upstream 100 bases:

>100_bases
TCTTAGTCTATTTTGCTTGATGTATGATGAATTTGTTCTAAATTCCCCTTGGATGACAATGGCATAATGCCAAGATATTT
AATGCATTAAGGAAGTTTCA

Downstream 100 bases:

>100_bases
CGACCGCATAGCATCGATACTTGTTGATGAAAGGGCGGGCTAAACACTGGAGTAGTATTCATGATGCGCATGGGCGTCGA
TTTAGGCGGAACAAAAATAG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTDKTTIAQTLTKQDLLQVVAIAKAAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAKQFVGIPIMSEEAA
DIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQAGQESPLLGA
KAPRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
DSGEPLTYNQKPDILNPYFIATAPGWVK

Sequences:

>Translated_268_residues
MTDKTTIAQTLTKQDLLQVVAIAKAAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAKQFVGIPIMSEEAA
DIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQAGQESPLLGA
KAPRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
DSGEPLTYNQKPDILNPYFIATAPGWVK
>Mature_267_residues
TDKTTIAQTLTKQDLLQVVAIAKAAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAKQFVGIPIMSEEAAD
IAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQAGQESPLLGAK
APRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCYD
SGEPLTYNQKPDILNPYFIATAPGWVK

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=28.2700421940928, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI116812595, Length=264, Percent_Identity=27.6515151515151, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1790659, Length=245, Percent_Identity=52.6530612244898, Blast_Score=223, Evalue=9e-60,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=29.4372294372294, Blast_Score=77, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71995905, Length=284, Percent_Identity=26.056338028169, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=284, Percent_Identity=26.056338028169, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537869, Length=288, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193202572, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651149, Length=270, Percent_Identity=28.1481481481481, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28938; Mature: 28807

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKTTIAQTLTKQDLLQVVAIAKAAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
IVAALAKQFVGIPIMSEEAADIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHHCCCCCCCCCHHCCHHHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLDTYYYGAKHLGAWRQQAGQESPLLGAKAPRAMPMIVGSRSHLSPGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
AQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
HHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
DSGEPLTYNQKPDILNPYFIATAPGWVK
CCCCCCEECCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TDKTTIAQTLTKQDLLQVVAIAKAAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHV
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
IVAALAKQFVGIPIMSEEAADIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHHCCCCCCCCCHHCCHHHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLDTYYYGAKHLGAWRQQAGQESPLLGAKAPRAMPMIVGSRSHLSPGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
AQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
HHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
DSGEPLTYNQKPDILNPYFIATAPGWVK
CCCCCCEECCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]