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The map label for this gene is gltT [H]

Identifier: 160874249

GI number: 160874249

Start: 1336614

End: 1337873

Strand: Reverse

Name: gltT [H]

Synonym: Sbal195_1129

Alternate gene names: 160874249

Gene position: 1337873-1336614 (Counterclockwise)

Preceding gene: 160874255

Following gene: 160874248

Centisome position: 25.02

GC content: 48.49

Gene sequence:

>1260_bases
ATGATCCTTCAAACCATTAGCCGCATTCCGTTTTGGCAAAAAGTCTTAGCAGGCTTTATCTTAGGTGCGCTCGTTGGCGT
TATTTTAGGTGAAAGCGCTACAGTGCTAAAACCACTCGGAGATCTGTTCATTGGCGCCATTAAGATGTTGGTCGCGCCTT
TGGTATTTTGTGCCATTGTCGTCAGTATCACGTCGCTAGGCTCGCAAACTAGCCTGAAACGCTTGAGCCTTAAAACCTTA
GGCATGTTCATGCTGACAGGCACGATTGCCTCGCTGATTGGCTTAGCCGTAGGTTCAATGATCGACATGGGCGGCACTAT
GCAGCTCACGGCAACGGAAGTGCGCGAGCGTAATATTCCCGGTTTTGCACAAGTGTTGCTCGATATGATACCAGTCAATC
CTTTCGCCTCACTGGCTGAAGGCAAGGTACTGCAAATTATCGTGTTTGCCGCGTTAGTGGGTATCGCTATCAATAAAGTC
GGCGAGAAAGCTGAGCCGCTAAAACGCACCATAGAAGCGGGCGCAGAAGTCATGTTCCAACTGACTCGCATGGTCTTAAA
ACTAACCCCTATCGGTGTGTTTGGTTTAATGGCTTGGGTTGTCGGTGAATACGGTTTATCAACTCTACTGCCTTTAGGTA
AGTTTATCGGGGCTATCTACATTGCCGCCTTTATCCACATCATCTTTGTCTACGGTGGCTTAGTGAAATTTGTCGGTGGT
TTAAGCCCACTGCAATTTTTCCGCAAAGCTATGCCAGCGCAGTTAGTCGCCTTTAGTACTTCTTCAAGTTTCGGTACTTT
ACCTGCGAGTACACGTGCAGTCGAAACCATGGGCGTATCAAAGCGTTATAGCGCCTTTGTGATGCCATTAGGTGCGACGA
TGAACATGGACGGCTGTGGGGGTATTTATCCTGCGATTGCCGCTATCTTCATCGCGCAGATTTACAATATTCCGCTCGAT
ACACTGGACTATGTGATGATTGCCGTGACTGCGACCGTCGCTTCTGTTGGTACCGCTGGCGTGCCGGGAAGTGCAATGGT
GATGTTAACTGTGACCTTAGGTGTGATTGGTCTGCCACTTGAAGGCATTGCCTTTATCGCCGCGATTGACCGTATTATCG
ATATGATCCGCACGGCAACGAACGTGACGGGCGATATGATGACAGCAGTCGTGATTGGTAAATCAGAAAATGAACTCGAT
GAAGCGCAGTTCTATTCGAACGATACCCAAGACGTTACACCTGTGAGTTCGCAGCAATAA

Upstream 100 bases:

>100_bases
ATGACTGAGAGCGCGTTAACATCACGCTCAACTCGTTGAATACGAATCCTATCATCGCAGGTCTATTGGCTCACTCTTAA
TTTATTTTTCTGGAATATGC

Downstream 100 bases:

>100_bases
CAATACTGGATCGAAGCCACTGCGCTAAACCATCAGTAACATTGCGTAAATTGCGCAGATGATGTAAATCAAGAGACCGC
TTAGGCGGTCTTTTTTATTA

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MILQTISRIPFWQKVLAGFILGALVGVILGESATVLKPLGDLFIGAIKMLVAPLVFCAIVVSITSLGSQTSLKRLSLKTL
GMFMLTGTIASLIGLAVGSMIDMGGTMQLTATEVRERNIPGFAQVLLDMIPVNPFASLAEGKVLQIIVFAALVGIAINKV
GEKAEPLKRTIEAGAEVMFQLTRMVLKLTPIGVFGLMAWVVGEYGLSTLLPLGKFIGAIYIAAFIHIIFVYGGLVKFVGG
LSPLQFFRKAMPAQLVAFSTSSSFGTLPASTRAVETMGVSKRYSAFVMPLGATMNMDGCGGIYPAIAAIFIAQIYNIPLD
TLDYVMIAVTATVASVGTAGVPGSAMVMLTVTLGVIGLPLEGIAFIAAIDRIIDMIRTATNVTGDMMTAVVIGKSENELD
EAQFYSNDTQDVTPVSSQQ

Sequences:

>Translated_419_residues
MILQTISRIPFWQKVLAGFILGALVGVILGESATVLKPLGDLFIGAIKMLVAPLVFCAIVVSITSLGSQTSLKRLSLKTL
GMFMLTGTIASLIGLAVGSMIDMGGTMQLTATEVRERNIPGFAQVLLDMIPVNPFASLAEGKVLQIIVFAALVGIAINKV
GEKAEPLKRTIEAGAEVMFQLTRMVLKLTPIGVFGLMAWVVGEYGLSTLLPLGKFIGAIYIAAFIHIIFVYGGLVKFVGG
LSPLQFFRKAMPAQLVAFSTSSSFGTLPASTRAVETMGVSKRYSAFVMPLGATMNMDGCGGIYPAIAAIFIAQIYNIPLD
TLDYVMIAVTATVASVGTAGVPGSAMVMLTVTLGVIGLPLEGIAFIAAIDRIIDMIRTATNVTGDMMTAVVIGKSENELD
EAQFYSNDTQDVTPVSSQQ
>Mature_419_residues
MILQTISRIPFWQKVLAGFILGALVGVILGESATVLKPLGDLFIGAIKMLVAPLVFCAIVVSITSLGSQTSLKRLSLKTL
GMFMLTGTIASLIGLAVGSMIDMGGTMQLTATEVRERNIPGFAQVLLDMIPVNPFASLAEGKVLQIIVFAALVGIAINKV
GEKAEPLKRTIEAGAEVMFQLTRMVLKLTPIGVFGLMAWVVGEYGLSTLLPLGKFIGAIYIAAFIHIIFVYGGLVKFVGG
LSPLQFFRKAMPAQLVAFSTSSSFGTLPASTRAVETMGVSKRYSAFVMPLGATMNMDGCGGIYPAIAAIFIAQIYNIPLD
TLDYVMIAVTATVASVGTAGVPGSAMVMLTVTLGVIGLPLEGIAFIAAIDRIIDMIRTATNVTGDMMTAVVIGKSENELD
EAQFYSNDTQDVTPVSSQQ

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=291, Percent_Identity=34.7079037800687, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI21314632, Length=442, Percent_Identity=28.7330316742081, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI169790839, Length=297, Percent_Identity=31.986531986532, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI194239697, Length=287, Percent_Identity=32.7526132404181, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI66773030, Length=276, Percent_Identity=34.4202898550725, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI223468566, Length=304, Percent_Identity=33.2236842105263, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI40254478, Length=289, Percent_Identity=32.1799307958478, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI223468564, Length=272, Percent_Identity=33.4558823529412, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5032093, Length=304, Percent_Identity=33.2236842105263, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI301601644, Length=206, Percent_Identity=34.9514563106796, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI262359914, Length=180, Percent_Identity=31.6666666666667, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790514, Length=413, Percent_Identity=35.3510895883777, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789947, Length=405, Percent_Identity=33.0864197530864, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1788024, Length=409, Percent_Identity=31.2958435207824, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789473, Length=376, Percent_Identity=22.8723404255319, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17537407, Length=438, Percent_Identity=28.7671232876712, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71996953, Length=471, Percent_Identity=28.2377919320594, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71983106, Length=442, Percent_Identity=28.9592760180996, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71983099, Length=442, Percent_Identity=28.9592760180996, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17541374, Length=439, Percent_Identity=26.4236902050114, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193206654, Length=428, Percent_Identity=27.5700934579439, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193206505, Length=411, Percent_Identity=25.7907542579075, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24583025, Length=447, Percent_Identity=25.7270693512304, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17137668, Length=447, Percent_Identity=25.7270693512304, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24583023, Length=447, Percent_Identity=25.7270693512304, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281360481, Length=465, Percent_Identity=27.0967741935484, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281360483, Length=465, Percent_Identity=27.0967741935484, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17137666, Length=465, Percent_Identity=27.0967741935484, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 44192; Mature: 44192

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILQTISRIPFWQKVLAGFILGALVGVILGESATVLKPLGDLFIGAIKMLVAPLVFCAIV
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSITSLGSQTSLKRLSLKTLGMFMLTGTIASLIGLAVGSMIDMGGTMQLTATEVRERNIP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCC
GFAQVLLDMIPVNPFASLAEGKVLQIIVFAALVGIAINKVGEKAEPLKRTIEAGAEVMFQ
HHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LTRMVLKLTPIGVFGLMAWVVGEYGLSTLLPLGKFIGAIYIAAFIHIIFVYGGLVKFVGG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSPLQFFRKAMPAQLVAFSTSSSFGTLPASTRAVETMGVSKRYSAFVMPLGATMNMDGCG
CCHHHHHHHHCCHHHEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHEEECCCEECCCCCC
GIYPAIAAIFIAQIYNIPLDTLDYVMIAVTATVASVGTAGVPGSAMVMLTVTLGVIGLPL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCH
EGIAFIAAIDRIIDMIRTATNVTGDMMTAVVIGKSENELDEAQFYSNDTQDVTPVSSQQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]