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The map label for this gene is rstB [H]

Identifier: 160874223

GI number: 160874223

Start: 1304269

End: 1305537

Strand: Reverse

Name: rstB [H]

Synonym: Sbal195_1103

Alternate gene names: 160874223

Gene position: 1305537-1304269 (Counterclockwise)

Preceding gene: 160874224

Following gene: 160874221

Centisome position: 24.41

GC content: 49.01

Gene sequence:

>1269_bases
GTGAAACGTCTCTTTATCAGTTTATATCTGCTACTCAGTCTCAGCGTGCTTGGGATTGGCTGGACACTCGACAGCCTGTG
GCAGAAAAATGTGGATGACAATAACGCCCTCGATGCGCCATTAGTGGCCTTGGCGCAATTGTTAGCGGAACTGCCTCCCG
ATACCCGCCAAAGGTATCTGGAGGCGATCCCAGTCAATCCTGTGATGCCGTTGCAATTGCTCAGTGCCGATCAAGTCGCG
CTAGCAGACAATCAAGCTCTCAGCACCAGTACTGTGTTCACCACCACGACCAATGACGATAACCTACTGCAATTTATCCG
AGTCGGCGATCAAGTCTTAATGGCGGGGCCGCTGGACATCGATCCCAGAGCCAACCTTCGCAGCCTGTTCACCCTGTTCT
TCTATTTATCACTCGCCCTGGTCGCGCTGATCTGGGTTGGCCCGCTTTCTCGGGATTTGAGCATACTGCGTAAAGCTACC
AAAGAGTTTGGCGAAGCCAAATGGAACACGCGGATTACCCTGTCAAATCGCTCTCAGGTCAAACCCTTAGCCAATACCTT
TAACGAAATGGCGCGGCATATCAGTGCCTTGATTGAGAACCAGAAACACCTGTCTAATGCGGTCTCCCATGAGATCCGTA
CGCCGCTGGCGAGGCTCAAATTCGCCCTTGCACTCATGCCCATGTATTGTCAGCCTGATTCGGACGAACAAAAGCGCCAA
GACTTTCTCGATGAAATGCAGCTCGATATCAAAGAAATGGAAGACTTGCTTCAGGAACTGCTAACCTACGCCAGCTTAGA
GTCCCAGCGAGAAGGTATCCAGTTAGATGAGTACGATTTAATTAATCTCATCAATCAAAGCATTAAGCGTCTAGAAAGCT
TGAGCCCAACACCTATTACCCTTAAAACAGAAGTCGAAAAACTGCCCTTGTTTGGGGAACCCGCATTAATTGAACGTGCG
CTGCAGAATTTACTGACCAATGCCCAACGCTTTGCCCGTACTGAAATCGTTATTGAAGTTAAGCAGACCCAGCATAGGGT
CAATTTAAGTGTGAGTAACGACGGCGAACCTATACCAGCAGTAGATTTACCTAAAGTGTTCGAGCCTTTTTATCGCAGCC
AATCGGTGCAAAATGGCAATAAGGGACACGGTTTGGGACTGGCGATCATTAAACGGATTATGCAGCGGCATCAAGGGAAT
GTGAGCGTCACCAGCGATGCGCAACATACCCGATTTAATTTAATTTGGCCGAAGAAGCGCAAGCTGTAA

Upstream 100 bases:

>100_bases
AACTCAACGATAATATCGAGACACCTTTCAGAATTAAAACCGTTTGGGGACAAGGTTACCTCTTTGCTCCTGAAGCCTGG
AATAACTAAGCACAGATACA

Downstream 100 bases:

>100_bases
TAGGGATTGGGATTAAACGACTGCGCATCTGTAATTCATCAATGCGCTAATTCTACAAGCCAGTAAAACAAGTGAGTGAA
ACAAGACTATTTAACTGGCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKRLFISLYLLLSLSVLGIGWTLDSLWQKNVDDNNALDAPLVALAQLLAELPPDTRQRYLEAIPVNPVMPLQLLSADQVA
LADNQALSTSTVFTTTTNDDNLLQFIRVGDQVLMAGPLDIDPRANLRSLFTLFFYLSLALVALIWVGPLSRDLSILRKAT
KEFGEAKWNTRITLSNRSQVKPLANTFNEMARHISALIENQKHLSNAVSHEIRTPLARLKFALALMPMYCQPDSDEQKRQ
DFLDEMQLDIKEMEDLLQELLTYASLESQREGIQLDEYDLINLINQSIKRLESLSPTPITLKTEVEKLPLFGEPALIERA
LQNLLTNAQRFARTEIVIEVKQTQHRVNLSVSNDGEPIPAVDLPKVFEPFYRSQSVQNGNKGHGLGLAIIKRIMQRHQGN
VSVTSDAQHTRFNLIWPKKRKL

Sequences:

>Translated_422_residues
MKRLFISLYLLLSLSVLGIGWTLDSLWQKNVDDNNALDAPLVALAQLLAELPPDTRQRYLEAIPVNPVMPLQLLSADQVA
LADNQALSTSTVFTTTTNDDNLLQFIRVGDQVLMAGPLDIDPRANLRSLFTLFFYLSLALVALIWVGPLSRDLSILRKAT
KEFGEAKWNTRITLSNRSQVKPLANTFNEMARHISALIENQKHLSNAVSHEIRTPLARLKFALALMPMYCQPDSDEQKRQ
DFLDEMQLDIKEMEDLLQELLTYASLESQREGIQLDEYDLINLINQSIKRLESLSPTPITLKTEVEKLPLFGEPALIERA
LQNLLTNAQRFARTEIVIEVKQTQHRVNLSVSNDGEPIPAVDLPKVFEPFYRSQSVQNGNKGHGLGLAIIKRIMQRHQGN
VSVTSDAQHTRFNLIWPKKRKL
>Mature_422_residues
MKRLFISLYLLLSLSVLGIGWTLDSLWQKNVDDNNALDAPLVALAQLLAELPPDTRQRYLEAIPVNPVMPLQLLSADQVA
LADNQALSTSTVFTTTTNDDNLLQFIRVGDQVLMAGPLDIDPRANLRSLFTLFFYLSLALVALIWVGPLSRDLSILRKAT
KEFGEAKWNTRITLSNRSQVKPLANTFNEMARHISALIENQKHLSNAVSHEIRTPLARLKFALALMPMYCQPDSDEQKRQ
DFLDEMQLDIKEMEDLLQELLTYASLESQREGIQLDEYDLINLINQSIKRLESLSPTPITLKTEVEKLPLFGEPALIERA
LQNLLTNAQRFARTEIVIEVKQTQHRVNLSVSNDGEPIPAVDLPKVFEPFYRSQSVQNGNKGHGLGLAIIKRIMQRHQGN
VSVTSDAQHTRFNLIWPKKRKL

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=433, Percent_Identity=29.3302540415704, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=30.0411522633745, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=26.7857142857143, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=26.3157894736842, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=301, Percent_Identity=25.2491694352159, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=28.310502283105, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=23.6641221374046, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=234, Percent_Identity=26.4957264957265, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=26.6968325791855, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=26.3888888888889, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47777; Mature: 47777

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLFISLYLLLSLSVLGIGWTLDSLWQKNVDDNNALDAPLVALAQLLAELPPDTRQRYL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
EAIPVNPVMPLQLLSADQVALADNQALSTSTVFTTTTNDDNLLQFIRVGDQVLMAGPLDI
HHCCCCCCCCHHHHCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCC
DPRANLRSLFTLFFYLSLALVALIWVGPLSRDLSILRKATKEFGEAKWNTRITLSNRSQV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
KPLANTFNEMARHISALIENQKHLSNAVSHEIRTPLARLKFALALMPMYCQPDSDEQKRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
DFLDEMQLDIKEMEDLLQELLTYASLESQREGIQLDEYDLINLINQSIKRLESLSPTPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
LKTEVEKLPLFGEPALIERALQNLLTNAQRFARTEIVIEVKQTQHRVNLSVSNDGEPIPA
EECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCCC
VDLPKVFEPFYRSQSVQNGNKGHGLGLAIIKRIMQRHQGNVSVTSDAQHTRFNLIWPKKR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCHHC
KL
CC
>Mature Secondary Structure
MKRLFISLYLLLSLSVLGIGWTLDSLWQKNVDDNNALDAPLVALAQLLAELPPDTRQRYL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
EAIPVNPVMPLQLLSADQVALADNQALSTSTVFTTTTNDDNLLQFIRVGDQVLMAGPLDI
HHCCCCCCCCHHHHCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCC
DPRANLRSLFTLFFYLSLALVALIWVGPLSRDLSILRKATKEFGEAKWNTRITLSNRSQV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
KPLANTFNEMARHISALIENQKHLSNAVSHEIRTPLARLKFALALMPMYCQPDSDEQKRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
DFLDEMQLDIKEMEDLLQELLTYASLESQREGIQLDEYDLINLINQSIKRLESLSPTPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
LKTEVEKLPLFGEPALIERALQNLLTNAQRFARTEIVIEVKQTQHRVNLSVSNDGEPIPA
EECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCCC
VDLPKVFEPFYRSQSVQNGNKGHGLGLAIIKRIMQRHQGNVSVTSDAQHTRFNLIWPKKR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCHHC
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]