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The map label for this gene is ywbI [H]

Identifier: 160874108

GI number: 160874108

Start: 1172403

End: 1173293

Strand: Reverse

Name: ywbI [H]

Synonym: Sbal195_0988

Alternate gene names: 160874108

Gene position: 1173293-1172403 (Counterclockwise)

Preceding gene: 160874114

Following gene: 160874106

Centisome position: 21.94

GC content: 52.41

Gene sequence:

>891_bases
ATGGACCTCAAAGTTATTCGCTATTTTATCGAAATCGTCGATGCCGGAGGCTTTGGTAAAGCCAGCGATAAAGTCCATCT
CACCCAACCTGCGTTATCAAAAGCCGTGCGCCAGTTAGAACAAGAACTCGATCTCACCCTGCTTGAGCGCGGTAAACGCG
GCACCCAAGTCAAACTCACTCCCGCAGGCGAAGTCGTTTATCGACACGGTAAAGACCTGCTCGCAGGGCGGCAACGCATG
CTCGCCGAACTCACGGCGCAGCGCAGCTTAACTGCGGGCGAACTCAATCTGGGATTAGCGCCGCTGGGCAGCGCCGAGAT
TTTTGCCCCCATTATTGCCAAGTATCGCCAGCAATATCCGCAAATTGATATGCACTTACTCGTCCGTGGCGGTGTAGAAC
AAACTTCGGCGATCCAAAAGGATGAGATTGAACTGGCCACAGGGATTATCGATTTTGATGACGGCTATGATGGGATTAGG
GTGTTTAACGATCCTATGGTAGTGGTGCTTCCCAAGGAAAATCCGTTATCCACCAGACAGATACTGTCGTTTAGGGATCT
CAGCGCCGATCCTCAAGTGATGTTCGAAACCGAATACACCCTCTATCAATTAGTACTCAATGCCTGCCGACACGCCGGAT
TTGTCCCTAAAAACATCACCCGCGTTAGCCAAGCCGATTTCGGGATTGCCTTAGTCGCGGCGGGCACTGGGGTGATGGTA
TTGCCGCGCTCTATCGCGCGGCGCTACAGTGTACCCGGCGTCGTGAATATCCCGCTGGCGAGTGACGAGCTGCGCTGGGA
GTTATCGCTCTTTTGGCGCAAAGACCAAGTATTGTCCTTTGCAGCTCAAGCCATGATCGCTTTAGTCGAGAAGCACTTAA
CTCATAAGTGA

Upstream 100 bases:

>100_bases
TTTTCTATGGGGCTATTCTAGGCTTGCTTATTTGATAAAAAAAATGAATATTAAGAATGTAATACATGAATTTTAAGAAT
GCATTTAAAGGTGAAGCCCA

Downstream 100 bases:

>100_bases
CACTATGTTACCAAGGGATCACTAAGCTCAAACGCACTAGCGTATCGCTATCCCATGGCAGAATAGGCAAATACTCAGCC
GAGTTAATATCGACTTTGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLKVIRYFIEIVDAGGFGKASDKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKDEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFRDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK

Sequences:

>Translated_296_residues
MDLKVIRYFIEIVDAGGFGKASDKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKDEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFRDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
>Mature_296_residues
MDLKVIRYFIEIVDAGGFGKASDKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKDEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFRDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=25, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=25, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=24.3986254295533, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=26.6211604095563, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=22.4913494809689, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788887, Length=302, Percent_Identity=26.8211920529801, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=27.8625954198473, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787806, Length=294, Percent_Identity=29.2517006802721, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789506, Length=291, Percent_Identity=20.6185567010309, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=252, Percent_Identity=23.015873015873, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=21.09375, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=257, Percent_Identity=21.7898832684825, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=22.7450980392157, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1789440, Length=126, Percent_Identity=31.7460317460317, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32880; Mature: 32880

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKVIRYFIEIVDAGGFGKASDKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEC
PAGEVVYRHGKDLLAGRQRMLAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYP
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTSAIQKDEIELATGIIDFDDGYDGIRVFNDPMVVVLPKENPLSTRQ
CCCEEEEEECCCCHHHHHCHHHHHHHEEEEECCCCCCCEEEECCCEEEEEECCCCCCHHH
ILSFRDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
ECHHHHHHCCCCCEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLKVIRYFIEIVDAGGFGKASDKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEC
PAGEVVYRHGKDLLAGRQRMLAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYP
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTSAIQKDEIELATGIIDFDDGYDGIRVFNDPMVVVLPKENPLSTRQ
CCCEEEEEECCCCHHHHHCHHHHHHHEEEEECCCCCCCEEEECCCEEEEEECCCCCCHHH
ILSFRDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
ECHHHHHHCCCCCEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]