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The map label for this gene is acoR [H]

Identifier: 160873378

GI number: 160873378

Start: 290025

End: 291983

Strand: Direct

Name: acoR [H]

Synonym: Sbal195_0252

Alternate gene names: 160873378

Gene position: 290025-291983 (Clockwise)

Preceding gene: 160873376

Following gene: 160873379

Centisome position: 5.42

GC content: 50.33

Gene sequence:

>1959_bases
ATGGCAGTTAAACCGCATTTACCATCGACACAGGCGTGGTTGGCCGATTCGTGGCAGCGCAGCATTGGCGCTGGCTTGTC
TGAATTTCAGTTACCCCAAGAGCTTAGGCTCGACGCCAGCGAACTAAAGCAGAAACATGAGCAATATCAAATGCTCATTG
CATTAGTGCAATCCCATGCTTTGCCCTTGTTCAATCAGTTGATGGCGCATTCTAATAGCCGACTCTTGCTCTCCGATGCC
GAGGGTTATGTGCTTAGGCACTGGGGCGTGAGCCGCTACTCCACAAAACTGGCGGACGTGGCTTTGGATATCGGGGTGAA
TTGGCTCGAACAGCACAAAGGCACCAATGCGATAGGGACGGCACTCACCGCCAAGCAAGCCGTATCTGTAGTGGGTGAGC
AGCATTTTATTCGTCAGAATCGTTTTATGAGTTGCACCGCCTGCCCGATATTTTCCCCCCAAGGTGAGATGCTCGGGGTG
ATAGATATCACCAGCGAGCAGCAAAGACACACCCAGCAGACGCTGATGTTAGTGTCGAGTTTGGCGCAGCAGGTCGAGAC
CGCACTTTTGTGTCATCTGCCCGATAGCCATTATCGAATCGATTTAGCGGCGCAGCCAAATTTACTGAATTCGGGTTGGC
AGGGCATAGTGATTGCCGACAGCGATGGCCGCATTGTGGGTTGTAATCCCATGGCGAAACAATTGCTTAATCAAGCCAAG
GTGGGTGATAGCGTTGAGCAGTACTTAGGCGATAATTGGAGCCGTGCGGGTGGTTTTAATCAGCATTTAGACTTGCATCT
ACAGACTCAGCCCTTAAACATTCCCAGCGCTAAGGGGCGAGTTGCGATGAGCAATAAATCGCTCACTCAACTGGGCGTGC
GGTTTCGCGATCCTCAACTTGAGCGCGCATGGCAACATGCCAATAAGGTGATCACCAAGCAAATTCCGCTGTTAGTGCTT
GGTGAAACCGGCGTCGGTAAAGAGCAGTTTGTTAAAAAACTCCACGCCCAGAGCGCGCGTCGCACCGAGCATTTAGTGGC
GGTGAACTGCGCGGCATTGCCTGCAGAGTTAGTCGAATCTGAACTCTTTGGTTATCAGGCGGGCGCGTTTACTGGGGCGA
ACCGCACTGGATTTATCGGCAAAATTCGCCAAGCCCACGGCGGTTTTTTGTTTTTAGATGAAATAGGTGAAATGCCGCTG
GCGGCACAGAGTCGTTTACTCAGGGTATTGCAGGAGCGCGAAGTGGTGCCCGTTGGCAGTAATCAAAGTTTTAAAGTTGA
TATTCAAATCATTGCCGCGACCCATATGGATTTGGAGCAACAAGTGGCGCAGGGGCTGTTTCGACAGGATTTATTCTATC
GATTAAATGGTCTACAAGTGCGTTTGCCTGCGCTGCGGGAGCGGCAGGATATCGAGCGCATTATCCATAAATTGCATCGT
AAACATCGCATTGCGCCGCAGGCGATCTGCCCAGAGTTGTTAGGGCAATTAATGCTACACGACTGGCCCGGCAATTTGCG
TGAGCTGGATAATCTTATGCAAGTCGCGTGTTTAATGGCTGAAGGTGATGACACCTTAACTTGGCAGCATTTACCCGATT
ATCTTGCACAAAAATTAGCGTGCGATCTGTTAAAAGTGGATCCGTTAAATGCACAGCTGTTAAACACACTGCAGTTAAAT
GAAGAGCAGCCATTAGGTGAAGAGGTTAAAATCGGTCAAAACTCTGCATCACATCCGCTGGCTGGCAAAGTTGTGAGTGG
CAAAGTTACGAGTGGCAACACTGCGACGCTGCCAACTGCCACTGCGGTTCAATCGGATTCTCTCCACGAGGCGATTTATA
GCAATGTGCTACAGGCATACAAAGCCTCTGATGGCAATGTGAGCCAATGCGCCAAGCGTTTGGGGATCAGCCGTAATGCC
TTGTATCGTCGATTAAAACAGATGGGACTTAAGGGTTAA

Upstream 100 bases:

>100_bases
GTGGGCACTCAGGGAGAGAGGTGTGTCCTGTGGTCACTTTGTCATCGAATGGCACATCGCAACTGTGCCGAAACGGAACA
CAGCTCGGGGGAGCACGGCT

Downstream 100 bases:

>100_bases
TATTAGCTCGCGGCGCTTATCAGTAAGTGTAATAAACAACGCAAAGCTCGCTTATCACGCCCATGACTAACCAACTCGCA
ATGGACTAAAACTGTGAGAT

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MAVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDA
EGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
IDITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNQAK
VGDSVEQYLGDNWSRAGGFNQHLDLHLQTQPLNIPSAKGRVAMSNKSLTQLGVRFRDPQLERAWQHANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
KHRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHLPDYLAQKLACDLLKVDPLNAQLLNTLQLN
EEQPLGEEVKIGQNSASHPLAGKVVSGKVTSGNTATLPTATAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNA
LYRRLKQMGLKG

Sequences:

>Translated_652_residues
MAVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDA
EGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGV
IDITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNQAK
VGDSVEQYLGDNWSRAGGFNQHLDLHLQTQPLNIPSAKGRVAMSNKSLTQLGVRFRDPQLERAWQHANKVITKQIPLLVL
GETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPL
AAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
KHRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHLPDYLAQKLACDLLKVDPLNAQLLNTLQLN
EEQPLGEEVKIGQNSASHPLAGKVVSGKVTSGNTATLPTATAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNA
LYRRLKQMGLKG
>Mature_651_residues
AVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHALPLFNQLMAHSNSRLLLSDAE
GYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGTALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVI
DITSEQQRHTQQTLMLVSSLAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNQAKV
GDSVEQYLGDNWSRAGGFNQHLDLHLQTQPLNIPSAKGRVAMSNKSLTQLGVRFRDPQLERAWQHANKVITKQIPLLVLG
ETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPAELVESELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLA
AQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHRK
HRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHLPDYLAQKLACDLLKVDPLNAQLLNTLQLNE
EQPLGEEVKIGQNSASHPLAGKVVSGKVTSGNTATLPTATAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNAL
YRRLKQMGLKG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=409, Percent_Identity=34.4743276283619, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082117, Length=249, Percent_Identity=44.9799196787149, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1790437, Length=253, Percent_Identity=41.501976284585, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1788905, Length=226, Percent_Identity=44.2477876106195, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1790299, Length=359, Percent_Identity=35.933147632312, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786524, Length=257, Percent_Identity=42.8015564202335, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=35.4748603351955, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789087, Length=212, Percent_Identity=45.7547169811321, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87082152, Length=246, Percent_Identity=39.4308943089431, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1787583, Length=251, Percent_Identity=36.2549800796813, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081872, Length=205, Percent_Identity=40.4878048780488, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=37.6, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI87081858, Length=630, Percent_Identity=23.015873015873, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72225; Mature: 72094

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHA
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDAEGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVIDITSEQQRHTQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHH
LAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNQAK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
VGDSVEQYLGDNWSRAGGFNQHLDLHLQTQPLNIPSAKGRVAMSNKSLTQLGVRFRDPQL
CCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHCCCCCCCHH
ERAWQHANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KHRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHLPDYLAQKLA
HHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
CDLLKVDPLNAQLLNTLQLNEEQPLGEEVKIGQNSASHPLAGKVVSGKVTSGNTATLPTA
HHHHHCCCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEECEECCCCCCCCCCH
TAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNALYRRLKQMGLKG
HHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVKPHLPSTQAWLADSWQRSIGAGLSEFQLPQELRLDASELKQKHEQYQMLIALVQSHA
CCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCC
LPLFNQLMAHSNSRLLLSDAEGYVLRHWGVSRYSTKLADVALDIGVNWLEQHKGTNAIGT
CHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
ALTAKQAVSVVGEQHFIRQNRFMSCTACPIFSPQGEMLGVIDITSEQQRHTQQTLMLVSS
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHH
LAQQVETALLCHLPDSHYRIDLAAQPNLLNSGWQGIVIADSDGRIVGCNPMAKQLLNQAK
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHH
VGDSVEQYLGDNWSRAGGFNQHLDLHLQTQPLNIPSAKGRVAMSNKSLTQLGVRFRDPQL
CCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHCCCCCCCHH
ERAWQHANKVITKQIPLLVLGETGVGKEQFVKKLHAQSARRTEHLVAVNCAALPAELVES
HHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHHCCHHHHHH
ELFGYQAGAFTGANRTGFIGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGS
HHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCEECCC
NQSFKVDIQIIAATHMDLEQQVAQGLFRQDLFYRLNGLQVRLPALRERQDIERIIHKLHR
CCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHH
KHRIAPQAICPELLGQLMLHDWPGNLRELDNLMQVACLMAEGDDTLTWQHLPDYLAQKLA
HHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
CDLLKVDPLNAQLLNTLQLNEEQPLGEEVKIGQNSASHPLAGKVVSGKVTSGNTATLPTA
HHHHHCCCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCEEECEECCCCCCCCCCH
TAVQSDSLHEAIYSNVLQAYKASDGNVSQCAKRLGISRNALYRRLKQMGLKG
HHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]