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The map label for this gene is selA [H]

Identifier: 160873235

GI number: 160873235

Start: 130431

End: 131861

Strand: Direct

Name: selA [H]

Synonym: Sbal195_0109

Alternate gene names: 160873235

Gene position: 130431-131861 (Clockwise)

Preceding gene: 160873234

Following gene: 160873236

Centisome position: 2.44

GC content: 50.87

Gene sequence:

>1431_bases
ATGACACAGATGATGACCCAAGCACCCGAAACGCCACAAGCCTTGTACCGCGCTTTGCCCTCAATGGACAGCTTACTGGC
GGAGCCTAGCTTTGTGGTATTGCAGCAGTCTTACGGCAAAGTGGCAGTAAAGACGGCGCTGGATAGCCAGTTAAAGGCGG
CGCGAAGCTTAATTAGCAGTGAGCGCCGTTTGCCGACATGGTGTGGCGAGCTTGCGCAATTGCACGGATGTTTGGTTGAT
CAACTGTCTAAAGATTACAGCCACAGCTTAATACCTGTGTGGAATCTTACTGGCACCATACTGCATACCAACCTTGGCCG
AGCGCAGCAGTCAGAAGCGGCAATTCGAGCCGTGACTTCTGTTATGCGCTACCCCACACCGCTGGAGTTTGAGCTTGCGG
CAGGTGAACGTGGTCACAGGGATAATGCAATCAGTGCTTTAATCCAGCGCTTAACGGGTGCCGAGGCTTGTTGTGTCGTG
AATAACAATGCCGCAGCTGTGTTGTTGATGCTGTCAGCTGTGGCTGCGGGGAAAGAAGTCATAGTCTCCCGTGGTGAGTT
GGTGGAAATTGGCGGCGCGTTTCGCATCCCTGACATTATGCGCCAAGCGGGCTGCACCTTAGTCGAGGTCGGCAGCACCA
ATCGGACTCACCTTAAGGATTATGAGCAGGCGATTACTGAAAATACCGCTGCAATAATGAAGGTCCACACCAGTAATTAT
CATATTAGTGGTTTTACTGCCGCAGTGGAGGAGGCAAGGCTGGGTCAGTTATGCCGTGAGCGTGGCATATCACTCATTTC
GGATCTTGGTAGTGGCTCACTGACGGACTTGCGCCGCTTTGGCCTAAAACAAGAACCTACGCCCCAAGCCATGCTGGCTG
ATGGGGTCGATTTAGTGAGTTTTTCTGGCGACAAATTATTGGGCGGTCCTCAATCGGGTTTAATTGTCGGCAAACAGTCG
CTGATTAAGCAGTTACAGAGTCATCCACTAAAGCGGGCCCTACGTTGCGATAAGCTGATTTTGGCGGCGTTAGAGGCAAC
ATTGATCCACTATCTTAACCCTGAAACCTTAGACTCTGAGCTGCCCATTATGGCGAAATTTGCCCGTAGCCAAGAGACGT
TATGGCAGATTGGTCATCGCTTACAGCAAGCTTTGGTTCCACACTTTGAACCTTGTTATCGTATTGAGTTAATTGAGTGC
CAAACACAGGTCGGCAGTGGCTCGCAGCCCGATACTTTTTTACCCTCAGTGGCGCTGTGTTTTATCGCACTCGATGGCGG
CAGTTTAAGTTTGTTAGAACAAAAATTTAAGCAGGCGGCACGCCCTATCATAGGTCGCATGAGTAACGATCAACTCAGAT
TGGATTTACGCGGTCTTGATAGCGAAGCCGAGCTACTCGCCGAGCTGAGCATATTAGGTGTGCAGTTGTGA

Upstream 100 bases:

>100_bases
GAAACCACGTAAGCCAAATAACTTAAGTCAATGCAGGAGGGAGTCGGGTTGCTGATCCCTTCCTGCTTTTTATCCAACAG
ATGACAATAACTTAAACAAG

Downstream 100 bases:

>100_bases
TCATTGTTACTGCGGGTCATGTCGATCACGGCAAGAGTACGCTTATTCGCGCCTTGACTGGGATGAATACCGATCGTCTG
CCGGAGGAGAAGCGCCGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTQMMTQAPETPQALYRALPSMDSLLAEPSFVVLQQSYGKVAVKTALDSQLKAARSLISSERRLPTWCGELAQLHGCLVD
QLSKDYSHSLIPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISALIQRLTGAEACCVV
NNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HISGFTAAVEEARLGQLCRERGISLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQS
LIKQLQSHPLKRALRCDKLILAALEATLIHYLNPETLDSELPIMAKFARSQETLWQIGHRLQQALVPHFEPCYRIELIEC
QTQVGSGSQPDTFLPSVALCFIALDGGSLSLLEQKFKQAARPIIGRMSNDQLRLDLRGLDSEAELLAELSILGVQL

Sequences:

>Translated_476_residues
MTQMMTQAPETPQALYRALPSMDSLLAEPSFVVLQQSYGKVAVKTALDSQLKAARSLISSERRLPTWCGELAQLHGCLVD
QLSKDYSHSLIPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISALIQRLTGAEACCVV
NNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HISGFTAAVEEARLGQLCRERGISLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQS
LIKQLQSHPLKRALRCDKLILAALEATLIHYLNPETLDSELPIMAKFARSQETLWQIGHRLQQALVPHFEPCYRIELIEC
QTQVGSGSQPDTFLPSVALCFIALDGGSLSLLEQKFKQAARPIIGRMSNDQLRLDLRGLDSEAELLAELSILGVQL
>Mature_475_residues
TQMMTQAPETPQALYRALPSMDSLLAEPSFVVLQQSYGKVAVKTALDSQLKAARSLISSERRLPTWCGELAQLHGCLVDQ
LSKDYSHSLIPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISALIQRLTGAEACCVVN
NNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNYH
ISGFTAAVEEARLGQLCRERGISLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQSL
IKQLQSHPLKRALRCDKLILAALEATLIHYLNPETLDSELPIMAKFARSQETLWQIGHRLQQALVPHFEPCYRIELIECQ
TQVGSGSQPDTFLPSVALCFIALDGGSLSLLEQKFKQAARPIIGRMSNDQLRLDLRGLDSEAELLAELSILGVQL

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=460, Percent_Identity=54.7826086956522, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 51767; Mature: 51636

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQMMTQAPETPQALYRALPSMDSLLAEPSFVVLQQSYGKVAVKTALDSQLKAARSLISS
CCCCCCCCCCCHHHHHHHCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
ERRLPTWCGELAQLHGCLVDQLSKDYSHSLIPVWNLTGTILHTNLGRAQQSEAAIRAVTS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHH
VMRYPTPLEFELAAGERGHRDNAISALIQRLTGAEACCVVNNNAAAVLLMLSAVAAGKEV
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHH
IVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HHCCCCEEEECCCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCE
HISGFTAAVEEARLGQLCRERGISLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVS
EECHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEE
FSGDKLLGGPQSGLIVGKQSLIKQLQSHPLKRALRCDKLILAALEATLIHYLNPETLDSE
CCCCCCCCCCCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
LPIMAKFARSQETLWQIGHRLQQALVPHFEPCYRIELIECQTQVGSGSQPDTFLPSVALC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHH
FIALDGGSLSLLEQKFKQAARPIIGRMSNDQLRLDLRGLDSEAELLAELSILGVQL
HEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQMMTQAPETPQALYRALPSMDSLLAEPSFVVLQQSYGKVAVKTALDSQLKAARSLISS
CCCCCCCCCCHHHHHHHCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
ERRLPTWCGELAQLHGCLVDQLSKDYSHSLIPVWNLTGTILHTNLGRAQQSEAAIRAVTS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHH
VMRYPTPLEFELAAGERGHRDNAISALIQRLTGAEACCVVNNNAAAVLLMLSAVAAGKEV
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHH
IVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HHCCCCEEEECCCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCE
HISGFTAAVEEARLGQLCRERGISLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVS
EECHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEE
FSGDKLLGGPQSGLIVGKQSLIKQLQSHPLKRALRCDKLILAALEATLIHYLNPETLDSE
CCCCCCCCCCCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
LPIMAKFARSQETLWQIGHRLQQALVPHFEPCYRIELIECQTQVGSGSQPDTFLPSVALC
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHH
FIALDGGSLSLLEQKFKQAARPIIGRMSNDQLRLDLRGLDSEAELLAELSILGVQL
HEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]