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The map label for this gene is pepQ [H]

Identifier: 160873147

GI number: 160873147

Start: 25841

End: 27163

Strand: Direct

Name: pepQ [H]

Synonym: Sbal195_0021

Alternate gene names: 160873147

Gene position: 25841-27163 (Clockwise)

Preceding gene: 160873140

Following gene: 160873148

Centisome position: 0.48

GC content: 46.86

Gene sequence:

>1323_bases
ATGGATCAGTTGGCTCATCACTATCGTGCCCATATTGCCGAGTTAAACCGTCGAGTCGCAGAGATTTTGTCTCGAGAAGC
CTTGTCTGGTTTAGTGATCCATTCGGGTCAGCCGCATCGGATGTTTTTGGATGATATCAATTATCCCTTTAAGGCAAACC
CGCACTTCAAGGCATGGTTGCCTGTGTTGGATAATCCGAATTGTTGGTTAGTGGTCAACGGCCGTGATAAGCCGCAGCTG
ATTTTTTATCGTCCTGTGGATTTTTGGCACAAAGTGTCTGATGTGCCTGATATGTTTTGGACTGAGTATTTCGATATTAA
GCTGCTGACCAAGGCTGATAAGGTCGCTGAGTTTTTACCGACAGATATCGCTAATTGGGCCTATTTAGGTGAGCATTTAG
ATGTGGCCGAAGTGCTGGGTTTTACCAGTCGTAATCCCGATGCTGTGATGAGTTATCTGCATTACCATAGAACGACTAAA
ACCGAATATGAGCTGGAATGCATGCGCCGCGCGAATCAAATTGCGGTGCAGGGACATTTGGCGGCTAAAAATGCCTTTTA
TAATGGTGCGAGCGAGTTCGAAATCCAGCAGCACTATTTATCTGCCGTAGGCCAGAGCGAAAATGAAGTGCCCTATGGCA
ATATCATCGCTCTTAACCAAAATGCGGCGATTTTGCATTACACCGCACTTGAACACCAAAGCCCTGCGAAACGTTTGTCA
TTTCTTATCGATGCCGGCGCGAGTTACTTTGGCTATGCCTCTGATATCACCAGAACTTATGCATTCGAGAAGAATCGTTT
CGATGAGTTGATCACTGCAATGAACAAGGCGCAGCTAGAGCTTATCGACATGATGCGTCCGGGTGTGCGTTATCCCGATT
TACACTTGGCCACCCATGCTAAAGTCGCGCAAATGCTATTGGATTTTGATTTAGCCACAGGTGATGTCCAAGGTTTGATT
GATCAAGGCATAACCAGTGCTTTCTTCCCCCATGGCTTAGGTCACATGTTAGGCCTACAAGTGCATGATGTTGGCGGCTT
CTCCCACGATGAACGCGGAACTCATATTGCGGCGCCAGAGGCCCATCCATTCCTACGTTGCACCCGCATTTTAGCGCCAA
ACCAAGTGCTGACCATGGAACCTGGGTTATACATTATCGATACTCTGCTCAATGAGCTTAAACAAGATAGTCGTGGCCAA
CAGATCAACTGGCAAACGGTTGATGAGTTAAGACCTTTTGGCGGTATTCGCATCGAAGATAACGTCATAGTGCATCAAGA
TAGAAACGAGAACATGACCCGTGAACTCGGTTTGACCGATTGA

Upstream 100 bases:

>100_bases
TTTAGTGTTTTGATTGAATCTGTTGTTCATGATCAGATTAAGATTATGTGAGCAAATTCGGCTCATATTATTAACTTTTA
TTCATTGCAGGAGATGACAA

Downstream 100 bases:

>100_bases
TCATAGGGTAAAGATTAGGGCGGATGTGTGCTCGAAAGTTATAGCGTTCCCTGTGAAGATATCGTGGTCGAAGAAGAGAT
AAAGCATAGCCGCTTTATCT

Product: proline dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQL
IFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLPTDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTK
TEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLS
FLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHAKVAQMLLDFDLATGDVQGLI
DQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQ
QINWQTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLTD

Sequences:

>Translated_440_residues
MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQL
IFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLPTDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTK
TEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLS
FLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHAKVAQMLLDFDLATGDVQGLI
DQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQ
QINWQTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLTD
>Mature_440_residues
MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQL
IFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLPTDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTK
TEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLS
FLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHAKVAQMLLDFDLATGDVQGLI
DQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQ
QINWQTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLTD

Specific function: Splits dipeptides with a prolyl residue in the C- terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI149589008, Length=289, Percent_Identity=33.9100346020761, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI260593665, Length=289, Percent_Identity=33.9100346020761, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI260593663, Length=446, Percent_Identity=27.5784753363229, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1790282, Length=443, Percent_Identity=49.6613995485327, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1789275, Length=286, Percent_Identity=31.8181818181818, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788728, Length=292, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=448, Percent_Identity=28.3482142857143, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321118, Length=290, Percent_Identity=32.0689655172414, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320922, Length=287, Percent_Identity=28.2229965156794, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357079, Length=454, Percent_Identity=25.5506607929515, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19920384, Length=304, Percent_Identity=28.6184210526316, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000994
- InterPro:   IPR001131
- InterPro:   IPR022846 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 50131; Mature: 50131

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEHHCCCCCCCCCCCCEEEE
PVLDNPNCWLVVNGRDKPQLIFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLP
EEECCCCEEEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHEEEEEECCHHHHHHHHC
TDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTKTEYELECMRRANQIAVQGHL
CHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEH
AAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEECCCCCHHHHHH
FLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHA
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
KVAQMLLDFDLATGDVQGLIDQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPE
HHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCHHHHHCEEEEECCCCCCCCCCCEEECCC
AHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQQINWQTVDELRPFGGIRIED
CCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCEEHHHCCCCCCEEEEC
NVIVHQDRNENMTRELGLTD
CEEEECCCCCCCHHHCCCCC
>Mature Secondary Structure
MDQLAHHYRAHIAELNRRVAEILSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEHHCCCCCCCCCCCCEEEE
PVLDNPNCWLVVNGRDKPQLIFYRPVDFWHKVSDVPDMFWTEYFDIKLLTKADKVAEFLP
EEECCCCEEEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHEEEEEECCHHHHHHHHC
TDIANWAYLGEHLDVAEVLGFTSRNPDAVMSYLHYHRTTKTEYELECMRRANQIAVQGHL
CHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEH
AAKNAFYNGASEFEIQQHYLSAVGQSENEVPYGNIIALNQNAAILHYTALEHQSPAKRLS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEEEECCCCCHHHHHH
FLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHA
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
KVAQMLLDFDLATGDVQGLIDQGITSAFFPHGLGHMLGLQVHDVGGFSHDERGTHIAAPE
HHHHHHHHHCCCCCHHHHHHHHCHHHHHHHCCHHHHHCEEEEECCCCCCCCCCCEEECCC
AHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQQINWQTVDELRPFGGIRIED
CCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCEEHHHCCCCCCEEEEC
NVIVHQDRNENMTRELGLTD
CEEEECCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA