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The map label for this gene is yveA

Identifier: 16080500

GI number: 16080500

Start: 3539165

End: 3540727

Strand: Direct

Name: yveA

Synonym: BSU34470

Alternate gene names: 16080500

Gene position: 3539165-3540727 (Clockwise)

Preceding gene: 16080499

Following gene: 16080501

Centisome position: 83.95

GC content: 46.26

Gene sequence:

>1563_bases
ATGTCTAAACAAGGAAATTTTCAAAAATCAATGTCGCTGTTTGATCTGATTTTGATTGGGATGGGAGCCATCTTTGGATC
AGCGTGGCTGTTCGCTGTCAGTAATGTCGCTTCAAAAGCAGGGCCCTCCGGCGCTTTTTCCTGGATCCTCGGAGGAGCCA
TTATTTTGTTAATCGGGCTTGTATATGCGGAGCTCGGAGCCGCTCTGCCCCGTACCGGAGGCATCATTCGATACCCCGTT
TATTCACATGGCCACCTTGTCGGCTACTTAATTTCGTTTGTCACGATTGTCGCTTATACAAGCTTGATTTCAATTGAAGT
GACAGCTGTGCGCCAGTATGTGGCCTATTGGTTTCCCGGCCTGACCATTAAAGGGTCTGATTCGCCTACCATTTCCGGCT
GGATCTTGCAGTTTGCCCTATTATGCTTGTTTTTCCTGCTGAATTATTGGAGCGTCAAAACCTTCGCTAAGGCGAATTTC
ATCATATCGATTTTTAAATATATTGTGCCGATTACCATCATTATTGTGCTGATCTTTCATTTTCAGCCGGAGAATTTATC
CGTTCAAGGATTTGCACCGTTTGGATTTACAGGTATTCAGGCTGCCATCTCGACAGGCGGCGTCATGTTTGCGTATCTCG
GCCTGCATCCGATTGTATCTGTAGCAGGTGAAGTCCAAAATCCAAAACGCAATATCCCGATCGCTTTAATCATTTGCATC
ATCGTTTCAACCATCATTTATACTGTTTTGCAGGTCACCTTTATTGGTGCAATCCCGACAGAAACACTGAAACATGGCTG
GCCGGCAATTGGCCGGGAGTTCTCATTGCCGTTTAAGGATATTGCGGTCATGCTCGGGTTAGGCTGGCTTGCAACGCTTG
TCATTTTAGACGCCATTCTGTCTCCCGGAGGAAACGGGAATATCTTTATGAATACGACATCCCGCCTTGTTTACGCCTGG
GCGCGTAACGGCACATTATTTGGCATATTCTCAAAGGTCAATAAAGATACGGGGACACCCCGCGCTTCGCTTTGGCTTTC
GTTTGCCCTGTCCATTTTCTGGACACTTCCCTTTCCTTCGTGGAACGCGCTCGTCAATGTCTGTTCAGTCGCGCTCATTC
TTTCATATGCGATTGCACCCATTTCTTCAGCTGCGCTGAGGGTCAACGCGAAGGACTTAAACAGGCCGTTTTATTTAAAG
GGAATGAGCATTATCGGGCCGCTTTCCTTTATATTTACAGCGTTTATCGTGTACTGGTCAGGATGGAAAACAGTCTCCTG
GCTGCTCGGTTCACAACTCGTGATGTTTTTGATCTATCTCTGTTTCAGCAAATATACGCCTAAAGAAGATGTCAGCCTTG
CTCAGCAGCTGAAATCAGCCTGGTGGCTTATCGGGTTTTATATTATGATGCTGATCTTTTCCTACATCGGTTCTTTCGGA
CATGGTTTAGGGATTATCAGCAATCCCGTCGACCTCATTTTAGTCGCGATCGGCTCACTTGCGATTTATTACTGGGCAAA
GTATACCGGGCTCCCAAAAGCCGCCATTGATTATGATAAATAA

Upstream 100 bases:

>100_bases
GGCGGCGCAGGCTGCCCCTGTTTTTTTATTAGGAGCGGTATTCTCTGTTACATATTGGGCATTGTAAGGAATATAAGGCT
GGTTTCAAAGGAGGAAGCGA

Downstream 100 bases:

>100_bases
AGAAGCAAGAGGTTTTCTTGCTTCTTTATTCTTTACAAACAAACATACACGCGATAAAATGAATGAGAGTCAGTCATTAC
TGGAGGTGTTCCTCATGCCA

Product: L-aspartate/L-glutamate permease

Products: NA

Alternate protein names: L-aspartate transporter

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGLVYAELGAALPRTGGIIRYPV
YSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANF
IISIFKYIVPITIIIVLIFHFQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICI
IVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAW
ARNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLK
GMSIIGPLSFIFTAFIVYWSGWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFG
HGLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK

Sequences:

>Translated_520_residues
MSKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGLVYAELGAALPRTGGIIRYPV
YSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANF
IISIFKYIVPITIIIVLIFHFQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICI
IVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAW
ARNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLK
GMSIIGPLSFIFTAFIVYWSGWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFG
HGLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK
>Mature_519_residues
SKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGLVYAELGAALPRTGGIIRYPVY
SHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANFI
ISIFKYIVPITIIIVLIFHFQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICII
VSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAWA
RNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLKG
MSIIGPLSFIFTAFIVYWSGWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFGH
GLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK

Specific function: Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family

Homologues:

Organism=Homo sapiens, GI110347453, Length=356, Percent_Identity=26.685393258427, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI187423910, Length=403, Percent_Identity=26.302729528536, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI7657591, Length=403, Percent_Identity=26.302729528536, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI258614005, Length=423, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI258614003, Length=423, Percent_Identity=23.4042553191489, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4507047, Length=453, Percent_Identity=22.7373068432671, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI114326544, Length=429, Percent_Identity=23.5431235431235, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI114326550, Length=429, Percent_Identity=23.5431235431235, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=22.9314420803783, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI9790235, Length=309, Percent_Identity=27.5080906148867, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI181337167, Length=396, Percent_Identity=22.979797979798, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI33286428, Length=436, Percent_Identity=26.1467889908257, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=364, Percent_Identity=26.3736263736264, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788480, Length=429, Percent_Identity=27.039627039627, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367353, Length=450, Percent_Identity=25.7777777777778, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082250, Length=365, Percent_Identity=26.8493150684932, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786302, Length=405, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790653, Length=345, Percent_Identity=22.3188405797101, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786602, Length=355, Percent_Identity=25.0704225352113, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081915, Length=416, Percent_Identity=21.6346153846154, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786789, Length=419, Percent_Identity=22.9116945107399, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994972, Length=367, Percent_Identity=25.0681198910082, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789017, Length=342, Percent_Identity=22.8070175438596, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786694, Length=464, Percent_Identity=23.2758620689655, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=407, Percent_Identity=26.7813267813268, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=353, Percent_Identity=27.4787535410765, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71995388, Length=421, Percent_Identity=24.7030878859857, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=421, Percent_Identity=24.7030878859857, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17532491, Length=406, Percent_Identity=26.3546798029557, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=312, Percent_Identity=28.2051282051282, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982608, Length=312, Percent_Identity=28.2051282051282, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17531343, Length=413, Percent_Identity=23.2445520581114, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=418, Percent_Identity=23.6842105263158, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71993915, Length=370, Percent_Identity=24.0540540540541, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71990446, Length=357, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=318, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208714, Length=318, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=317, Percent_Identity=24.2902208201893, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24667468, Length=395, Percent_Identity=26.8354430379747, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24668806, Length=438, Percent_Identity=22.6027397260274, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356285, Length=438, Percent_Identity=22.6027397260274, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24668802, Length=438, Percent_Identity=22.6027397260274, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221331183, Length=352, Percent_Identity=26.7045454545455, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17647653, Length=352, Percent_Identity=26.7045454545455, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664379, Length=352, Percent_Identity=26.7045454545455, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221512776, Length=419, Percent_Identity=22.9116945107399, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=23.0769230769231, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357367, Length=357, Percent_Identity=26.3305322128852, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550968, Length=400, Percent_Identity=25.5, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921172, Length=400, Percent_Identity=25.5, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641995, Length=352, Percent_Identity=25.8522727272727, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641993, Length=352, Percent_Identity=25.8522727272727, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651635, Length=398, Percent_Identity=24.1206030150754, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651633, Length=398, Percent_Identity=24.1206030150754, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPP_BACSU (O07002)

Other databases:

- EMBL:   Z94043
- EMBL:   AL009126
- PIR:   D70035
- RefSeq:   NP_391327.1
- ProteinModelPortal:   O07002
- SMR:   O07002
- EnsemblBacteria:   EBBACT00000001683
- GeneID:   938612
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU34470
- NMPDR:   fig|224308.1.peg.3453
- GenoList:   BSU34470
- GeneTree:   EBGT00070000031736
- HOGENOM:   HBG710413
- OMA:   LISINGM
- ProtClustDB:   CLSK2752518
- BioCyc:   BSUB:BSU34470-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 56989; Mature: 56858

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x110c8954)-; HASH(0x40c2aa6c)-; HASH(0x126ec074)-; HASH(0x40c0d9e4)-; HASH(0x40c0b380)-; HASH(0x11f2cf9c)-; HASH(0x12168600)-; HASH(0x11f9bd08)-; HASH(0x1282e4ac)-; HASH(0x119115c0)-; HASH(0x122ed638)-; HASH(0xdcd5a70)-; HASH(0x40c2056c)-; HASH(0x10138b50)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VYAELGAALPRTGGIIRYPVYSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPG
HHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANFIISIFKYIVPITIIIVLIFH
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICI
CCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
IVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAIL
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SPGGNGNIFMNTTSRLVYAWARNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPS
CCCCCCCEEEECCCCEEEEEECCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
WNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLKGMSIIGPLSFIFTAFIVYWS
HHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCEEECCCHHHHHHHHHHHHHHHHHC
GWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFG
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HGLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
SKQGNFQKSMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGAFSWILGGAIILLIGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VYAELGAALPRTGGIIRYPVYSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPG
HHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIKGSDSPTISGWILQFALLCLFFLLNYWSVKTFAKANFIISIFKYIVPITIIIVLIFH
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQPENLSVQGFAPFGFTGIQAAISTGGVMFAYLGLHPIVSVAGEVQNPKRNIPIALIICI
CCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
IVSTIIYTVLQVTFIGAIPTETLKHGWPAIGREFSLPFKDIAVMLGLGWLATLVILDAIL
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SPGGNGNIFMNTTSRLVYAWARNGTLFGIFSKVNKDTGTPRASLWLSFALSIFWTLPFPS
CCCCCCCEEEECCCCEEEEEECCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
WNALVNVCSVALILSYAIAPISSAALRVNAKDLNRPFYLKGMSIIGPLSFIFTAFIVYWS
HHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCEEECCCHHHHHHHHHHHHHHHHHC
GWKTVSWLLGSQLVMFLIYLCFSKYTPKEDVSLAQQLKSAWWLIGFYIMMLIFSYIGSFG
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HGLGIISNPVDLILVAIGSLAIYYWAKYTGLPKAAIDYDK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183