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The map label for this gene is fhuD

Identifier: 16080386

GI number: 16080386

Start: 3418474

End: 3419421

Strand: Direct

Name: fhuD

Synonym: BSU33320

Alternate gene names: 16080386

Gene position: 3418474-3419421 (Clockwise)

Preceding gene: 16080378

Following gene: 16080388

Centisome position: 81.09

GC content: 43.99

Gene sequence:

>948_bases
ATGACCCATATATACAAGAAACTCGGAGCCGCGTTTTTTGCCCTGTTATTGATTGCAGCGCTGGCAGCCTGCGGGAATAA
CTCAGAAAGCAAAGGTTCTGCCTCTGATTCAAAAGGCGCAGAAACCTTTACATACAAGGCTGAAAACGGAAATGTAAAAA
TCCCGAAGCATCCTAAACGGGTGGTTGTCATGGCAGACGGCTATTACGGCTACTTCAAAACACTCGGCATCAACGTTGTA
GGTGCGCCTGAGAATGTATTTAAAAACCCTTACTACAAAGGAAAAACCAACGGCGTCGAAAACATCGGAGACGGCACTTC
GGTTGAAAAGGTCATTGATTTGAACCCTGACCTGATTATCGTCTGGACAACACAGGGCGCTGATATTAAAAAGCTTGAAA
AAATTGCGCCGACTGTCGCAGTAAAATACGATAAGCTCGACAACATCGAACAGCTGAAAGAATTTGCAAAAATGACGGGA
ACTGAAGATAAAGCTGAAAAATGGCTGGCCAAGTGGGATAAAAAAGTTGCGGCCGCTAAAACAAAAATCAAAAAAGCGGT
CGGTGACAAAACCATTTCCATTATGCAAACGAACGGAAAAGACATTTACGTATTTGGTAAAGACTTTGGAAGAGGCGGAA
GCATCATTTACAAAGACCTCGGCCTGCAGGCTACAAAGCTGACAAAAGAAAAAGCCATTGACCAGGGGCCAGGTTATACA
AGTATTTCATTAGAGAAGCTCCCTGACTTCGCCGGAGATTACATTTTCGCGGGCCCATGGCAATCAGGCGGTGATGATGG
CGGCGTTTTTGAAAGCTCCATTTGGAAGAACCTGAATGCCGTTAAAAATGGCCATGTATACAAGATGGATCCGATCGGAT
TCTATTTCACAGACCCGATTTCATTAGAAGGACAACTGGAGTTTATTACGGAAAGCTTGACTAAATAA

Upstream 100 bases:

>100_bases
CATTTGCAAAAATATCGTGTCAACCGGCACTTGCAGTGGTATAATCACAGATGATAATGATTCTCTTTTTCATCTATCTT
TTAGAAAGAAGGTATGAGAT

Downstream 100 bases:

>100_bases
ACAAAAGAGCCGCCTGCCCGCGGCTCTTTTGCTTATTTATAAGGAACGGCTCAATTTGAATCATATCGGATATTTTCTTT
GAGCCATTCATATTAAGCTG

Product: ferrichrome ABC transporter ferrichrome-binding lipoprotein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding protein; Iron(III)-hydroxamate-binding protein fhuD

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTHIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFTYKAENGNVKIPKHPKRVVVMADGYYGYFKTLGINVV
GAPENVFKNPYYKGKTNGVENIGDGTSVEKVIDLNPDLIIVWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTG
TEDKAEKWLAKWDKKVAAAKTKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYKDLGLQATKLTKEKAIDQGPGYT
SISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWKNLNAVKNGHVYKMDPIGFYFTDPISLEGQLEFITESLTK

Sequences:

>Translated_315_residues
MTHIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFTYKAENGNVKIPKHPKRVVVMADGYYGYFKTLGINVV
GAPENVFKNPYYKGKTNGVENIGDGTSVEKVIDLNPDLIIVWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTG
TEDKAEKWLAKWDKKVAAAKTKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYKDLGLQATKLTKEKAIDQGPGYT
SISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWKNLNAVKNGHVYKMDPIGFYFTDPISLEGQLEFITESLTK
>Mature_314_residues
THIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFTYKAENGNVKIPKHPKRVVVMADGYYGYFKTLGINVVG
APENVFKNPYYKGKTNGVENIGDGTSVEKVIDLNPDLIIVWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTGT
EDKAEKWLAKWDKKVAAAKTKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYKDLGLQATKLTKEKAIDQGPGYTS
ISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWKNLNAVKNGHVYKMDPIGFYFTDPISLEGQLEFITESLTK

Specific function: Part of the ABC transporter complex fhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FHUD_BACSU (P37580)

Other databases:

- EMBL:   M87283
- EMBL:   X93092
- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   S32930
- RefSeq:   NP_391213.1
- PDB:   3G9Q
- PDB:   3HXP
- PDBsum:   3G9Q
- PDBsum:   3HXP
- ProteinModelPortal:   P37580
- SMR:   P37580
- EnsemblBacteria:   EBBACT00000003516
- GeneID:   935996
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33320
- NMPDR:   fig|224308.1.peg.3339
- GenoList:   BSU33320
- GeneTree:   EBGT00070000031847
- HOGENOM:   HBG692908
- OMA:   DPISLEG
- PhylomeDB:   P37580
- ProtClustDB:   CLSK887867
- BioCyc:   BSUB:BSU33320-MONOMER
- InterPro:   IPR002491

Pfam domain/function: PF01497 Peripla_BP_2

EC number: NA

Molecular weight: Translated: 34427; Mature: 34295

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50983 FE_B12_PBP; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFTYKAENGNVKIPKHPKR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCE
VVVMADGYYGYFKTLGINVVGAPENVFKNPYYKGKTNGVENIGDGTSVEKVIDLNPDLII
EEEEECCCCEEEHHCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEE
VWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTGTEDKAEKWLAKWDKKVAAAK
EEECCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYKDLGLQATKLTKEKAIDQGPGYT
HHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
SISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWKNLNAVKNGHVYKMDPIGFYFTDPI
EEEHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCC
SLEGQLEFITESLTK
CCCCHHHHHHHHHCC
>Mature Secondary Structure 
THIYKKLGAAFFALLLIAALAACGNNSESKGSASDSKGAETFTYKAENGNVKIPKHPKR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCE
VVVMADGYYGYFKTLGINVVGAPENVFKNPYYKGKTNGVENIGDGTSVEKVIDLNPDLII
EEEEECCCCEEEHHCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEE
VWTTQGADIKKLEKIAPTVAVKYDKLDNIEQLKEFAKMTGTEDKAEKWLAKWDKKVAAAK
EEECCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TKIKKAVGDKTISIMQTNGKDIYVFGKDFGRGGSIIYKDLGLQATKLTKEKAIDQGPGYT
HHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCC
SISLEKLPDFAGDYIFAGPWQSGGDDGGVFESSIWKNLNAVKNGHVYKMDPIGFYFTDPI
EEEHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCC
SLEGQLEFITESLTK
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8388528; 9639930; 9384377