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The map label for this gene is ysbA

Identifier: 16079943

GI number: 16079943

Start: 2955209

End: 2955649

Strand: Reverse

Name: ysbA

Synonym: BSU28910

Alternate gene names: 16079943

Gene position: 2955649-2955209 (Counterclockwise)

Preceding gene: 16079944

Following gene: 16079942

Centisome position: 70.11

GC content: 41.72

Gene sequence:

>441_bases
ATGAGTGCTAAAAAAGTGTACGGGTTTTTAACACAAGCATTTATTTTTGCCGTCATTATGCTGGTTTCAAATATGATTGC
CGCTATTGTCCCAATACCTATCCCGGCATCGGTTGTAGGGTTGGTCTTATTATTTCTCCTATTATGTTTGAAAGTCATTA
AACTGGAACAAGTGGAGACGCTCGGAACGTCTTTAACCTCTCTGATCGGATTTTTATTTGTTCCATCAGGTATATCTGTT
ATGAATTCGCTTGGTGTGATGCAGCAATACGGCCTGCAAATTGTTCTTGTCATTCTGCTCGCAACGATTATTTTGCTGGG
GGCTACGGGATTGTTTTCTCAGCTGATTCTGTCGCTGAGCGGAAAACGCAAAACCGAAGCGGACATGAAAACAAAAACAG
TGCAAAGCCCGCAGAACAATAACGAACTCGTTCACCATTAA

Upstream 100 bases:

>100_bases
TGCAACTCAGACCCGCTATACGGCATGTTATCTTGTAAGCGCTTTATAACAGGGAATTCTTATTTATAATGAGGGTACCA
AAGAGAAAGAGGTGAAGAAA

Downstream 100 bases:

>100_bases
GGGAAACAGGAGGTTCTTCACATGGAAAGCACAATGAGTCCTTATTTTGGGATTGTCGTATCACTTGCTGCATTCGGCAT
CGGCACCTTTTTATTTAAGA

Product: murein hydrolase regulator LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLLFLLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISV
MNSLGVMQQYGLQIVLVILLATIILLGATGLFSQLILSLSGKRKTEADMKTKTVQSPQNNNELVHH

Sequences:

>Translated_146_residues
MSAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLLFLLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISV
MNSLGVMQQYGLQIVLVILLATIILLGATGLFSQLILSLSGKRKTEADMKTKTVQSPQNNNELVHH
>Mature_145_residues
SAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLLFLLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISVM
NSLGVMQQYGLQIVLVILLATIILLGATGLFSQLILSLSGKRKTEADMKTKTVQSPQNNNELVHH

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LRGA_BACSU (P94515)

Other databases:

- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   C69983
- RefSeq:   NP_390769.1
- ProteinModelPortal:   P94515
- EnsemblBacteria:   EBBACT00000001385
- GeneID:   937417
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28910
- NMPDR:   fig|224308.1.peg.2894
- GenoList:   BSU28910
- GeneTree:   EBGT00070000032154
- HOGENOM:   HBG338218
- OMA:   QAFIFAV
- ProtClustDB:   PRK04125
- BioCyc:   BSUB:BSU28910-MONOMER
- GO:   GO:0019835
- HAMAP:   MF_01141
- InterPro:   IPR005538

Pfam domain/function: PF03788 LrgA

EC number: NA

Molecular weight: Translated: 15711; Mature: 15580

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd943880)-; HASH(0x10c50680)-; HASH(0x1149619c)-; HASH(0x10f4afc4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLLFLLLCLKVIKLEQVET
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTSLTSLIGFLFVPSGISVMNSLGVMQQYGLQIVLVILLATIILLGATGLFSQLILSLS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GKRKTEADMKTKTVQSPQNNNELVHH
CCCCHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
SAKKVYGFLTQAFIFAVIMLVSNMIAAIVPIPIPASVVGLVLLFLLLCLKVIKLEQVET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTSLTSLIGFLFVPSGISVMNSLGVMQQYGLQIVLVILLATIILLGATGLFSQLILSLS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GKRKTEADMKTKTVQSPQNNNELVHH
CCCCHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377