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The map label for this gene is fchA [H]

Identifier: 159900983

GI number: 159900983

Start: 5715949

End: 5716581

Strand: Direct

Name: fchA [H]

Synonym: Haur_4470

Alternate gene names: 159900983

Gene position: 5715949-5716581 (Clockwise)

Preceding gene: 159900982

Following gene: 159900984

Centisome position: 90.06

GC content: 53.55

Gene sequence:

>633_bases
ATGACCCTATTACAGGTGCCAATCACCGAATTTTTGGATCAGCTTGCAACCAAGGAGCCAGTGCCAGGTGGCGGTAGTGT
TGCAGCCGTGTCTGGGGCGATGGCCGCAGGCTTGATTTCAATGGTTTGTTCGTTGACCCTTGGCAAAAAGAAGTATGCCG
AGGTCGAGGATGAAATTCGTGGTTTGATGGATCGCTCTGAGTCGTTGCGCCGTGAATTGCAAGAGCTAGCCGATGCTGAT
GTTGAGGCATTTCGCCGTTTGAGCGCCGCCTATAAATTGCCGCGTGAAACTACTGCCGATATTGCGATTCGCCGCGATGC
CATTCAAAAAGCCACGCGGATTGCGACTGATGTGCCGTTGCGGGCGGCTCAAGCGGCAGCGGCAATTTTGCCATTGTGTA
GTCCAGCCGCTCAAAAAGGTAATTCAGCGGCAGTGAGCGATGTGGGCGTGGCGGTGCTCTTGGCTCAGGCGGCGGTACGC
AGCGCCTTGCTCAACGTTGAAATTAATCTTAACACGCTCGAAGATCAATTTTATGTGCGCGAAACTCGTGCCGAGGTTGC
CAAACTAACTGCAACCCTGCACGACGATACTGAGGCCGTGATGGCCTTAGTCAATCAACAGCTTCAGGGCTAA

Upstream 100 bases:

>100_bases
GGGCCACTTTAAGCAACCATGGATCGGAATCGAGCGACTGCACGTATGCTTAGATGTGGTACGATCAGCATGAACTTGAT
TCAACACCAAGGAGGTCGTT

Downstream 100 bases:

>100_bases
ATGGTTTTCCAACGATGGCGGAGCGCAGGCTCCGCCTTTTATTTGTAAAGGATGTTATGACAGCGCTTTTGCTTGATGGT
CGCGGGTTGGCCAAGGAATT

Product: formiminotransferase-cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIRGLMDRSESLRRELQELADAD
VEAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPLRAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVR
SALLNVEINLNTLEDQFYVRETRAEVAKLTATLHDDTEAVMALVNQQLQG

Sequences:

>Translated_210_residues
MTLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIRGLMDRSESLRRELQELADAD
VEAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPLRAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVR
SALLNVEINLNTLEDQFYVRETRAEVAKLTATLHDDTEAVMALVNQQLQG
>Mature_209_residues
TLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIRGLMDRSESLRRELQELADADV
EAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPLRAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVRS
ALLNVEINLNTLEDQFYVRETRAEVAKLTATLHDDTEAVMALVNQQLQG

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=150, Percent_Identity=32, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI11140815, Length=150, Percent_Identity=32, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22356; Mature: 22225

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIR
CCEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
GLMDRSESLRRELQELADADVEAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
RAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVRSALLNVEINLNTLEDQFYVR
HHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
ETRAEVAKLTATLHDDTEAVMALVNQQLQG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLQVPITEFLDQLATKEPVPGGGSVAAVSGAMAAGLISMVCSLTLGKKKYAEVEDEIR
CEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
GLMDRSESLRRELQELADADVEAFRRLSAAYKLPRETTADIAIRRDAIQKATRIATDVPL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
RAAQAAAAILPLCSPAAQKGNSAAVSDVGVAVLLAQAAVRSALLNVEINLNTLEDQFYVR
HHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHH
ETRAEVAKLTATLHDDTEAVMALVNQQLQG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]