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The map label for this gene is nagD [H]

Identifier: 159899887

GI number: 159899887

Start: 4250376

End: 4251149

Strand: Direct

Name: nagD [H]

Synonym: Haur_3370

Alternate gene names: 159899887

Gene position: 4250376-4251149 (Clockwise)

Preceding gene: 159899886

Following gene: 159899891

Centisome position: 66.97

GC content: 51.42

Gene sequence:

>774_bases
ATGAATCAATTTGATGATGTACGCGCCGTGTTATGCGATATGGATGGGGTTTTAGTTCACGGCGCACAAATTATCCCTGG
CGCACCGGAGTTTTTGGGTCGGCTACGGGCTTCAGGCCGTAAATTTTTAGTTTTGACCAATAATTCAATTTATACTCCTC
GCGATTTACAGGCTCGTTTGGCTCGCATCGGCCTGCCGCTCGAAATTGAAGATATTTATACCTCAGCCCTCGCTACCGCC
AAATTTCTCGATTCGCAACGCCCGAATGGTACAGCCTTTGTGATTGGTGAAGCTGGATTGACCAATGCGCTCTACGATGT
TGGCTACACCATGACTGAGCACGATCCCGATTATGTGGTGATTGGCGAAACCACCTCGTATAGTTTTGAGCGCATCACCC
AAGCTGTGCGTTTTGTCGCCGCTGGCTCACGTTTGATTGGCACCAATCCTGATGTTTCGGGGCCATCGGAGCGCGGAATT
TTGCCCGCATGTGGGGCAGTTGTGGCGTTAATTCGCGCTGCCACCAACGCCGAAGCTTATTTTGTGGGCAAGCCCAACCC
CGTGATGATGCGAACCGCTTTGCGCACCATCGACTCGCACGCTGCCGAAGCTATGATGATCGGCGACCGTATGGATACCG
ACATTATCGGCGGAACCGAGTCAGGCATGCGTACAGCCTTGGTACTTTCAGGCATGATGACCCGCCTTGATGCCGAGCGC
TATCCTTATCGCCCAACCGCAATTATTGAATCAGTCGCTGAATTATTCAATTAA

Upstream 100 bases:

>100_bases
TTCTCCGTTAGCTTTTAATCTTCATCCCTCATCCTTCATCCTTCATCCTTTCGGATTATAATAGGCCTATCGTCCCGCAC
TTTGTTTTGGGAGGCTTAAG

Downstream 100 bases:

>100_bases
ACAACAAATGTCCGCTGGGATTAATCAGCGGACATTTGATTTAACGCTTATTTAGACAGCGACTTTGGCACTTGCTCCAA
CGCTGACGGTTTGTTCGCCC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARLARIGLPLEIEDIYTSALATA
KFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVVIGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGI
LPACGAVVALIRAATNAEAYFVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAER
YPYRPTAIIESVAELFN

Sequences:

>Translated_257_residues
MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARLARIGLPLEIEDIYTSALATA
KFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVVIGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGI
LPACGAVVALIRAATNAEAYFVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAER
YPYRPTAIIESVAELFN
>Mature_257_residues
MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARLARIGLPLEIEDIYTSALATA
KFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVVIGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGI
LPACGAVVALIRAATNAEAYFVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAER
YPYRPTAIIESVAELFN

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=273, Percent_Identity=32.2344322344322, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI108796653, Length=291, Percent_Identity=29.553264604811, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI14149777, Length=246, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI269847098, Length=257, Percent_Identity=24.9027237354086, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786890, Length=249, Percent_Identity=42.1686746987952, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17558880, Length=255, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562458, Length=249, Percent_Identity=27.3092369477912, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560956, Length=249, Percent_Identity=27.3092369477912, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562356, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193210059, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563050, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319965, Length=239, Percent_Identity=25.5230125523013, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24666141, Length=255, Percent_Identity=29.0196078431373, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24656326, Length=254, Percent_Identity=24.4094488188976, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920940, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656330, Length=274, Percent_Identity=25.9124087591241, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666137, Length=297, Percent_Identity=25.5892255892256, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18859765, Length=280, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27812; Mature: 27812

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARL
CCCHHHHHHHHHCCCCEEEECCEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
ARIGLPLEIEDIYTSALATAKFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVV
HHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEECCCCCCEEE
IGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGILPACGAVVALIRAATNAEAY
EECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
FVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAER
EECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YPYRPTAIIESVAELFN
CCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MNQFDDVRAVLCDMDGVLVHGAQIIPGAPEFLGRLRASGRKFLVLTNNSIYTPRDLQARL
CCCHHHHHHHHHCCCCEEEECCEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
ARIGLPLEIEDIYTSALATAKFLDSQRPNGTAFVIGEAGLTNALYDVGYTMTEHDPDYVV
HHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEECCCCCCEEE
IGETTSYSFERITQAVRFVAAGSRLIGTNPDVSGPSERGILPACGAVVALIRAATNAEAY
EECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
FVGKPNPVMMRTALRTIDSHAAEAMMIGDRMDTDIIGGTESGMRTALVLSGMMTRLDAER
EECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YPYRPTAIIESVAELFN
CCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]