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The map label for this gene is 159899885

Identifier: 159899885

GI number: 159899885

Start: 4248118

End: 4248984

Strand: Direct

Name: 159899885

Synonym: Haur_3368

Alternate gene names: NA

Gene position: 4248118-4248984 (Clockwise)

Preceding gene: 159899884

Following gene: 159899886

Centisome position: 66.94

GC content: 53.98

Gene sequence:

>867_bases
ATGAACACACTACCATTCTTTCGATTGGCGATGCGTTGGCTGCCGCGACTCCCTAATTGGCTGGTCGATGCAGCCTGTGA
TCTTTTAGGGGTCGGCTTGCTGGCTATCCCTCGCTTGCGCCATAACACCCGTTCGAACCTCAAGCGGATTGCTCCAAAAA
CCCAAGGCTTGGCTCGTTGGTATTTGCAATCGCGCGTGCTGGCAAACTCCTTGCGCCATTATGCCGATCTGGTGCGGCTT
CCAGCTTGGAGTTCCGAGCAACTGCGCCAACGCTTCGAGCATTCGGGTTTAGAACACTTACGCCAATTAACTGAAACTGG
CGGCTTAGTCATCGTCGCGCATACTGGCTCGTTTAGCACTGGCCTTTCGGTTTTAGCGGCTCATGGCTTGCCAGTTGTAC
TGGTTGTTGAGGCAATCGAGCCACCAGAACATTTGGAACTTGTCAAGGAATTACGCGCAGCCCATGGCGGCGAATTGATT
GTGCTGGGGCCAAACGCTGGGCGTGAAGTGCTCAAGGCGTTACGTGCCAAAAAATTAGTGGTGCTAGCAGGTGATCGCGA
TCTGGCGGCTCAATCAATTAAGTTGCCGTTTTTTGGTGAGCCAGCCGATGTGCCAATTGGCCCAGCTCGCTTGGCTTTAC
GCGGCTGGCCAGTGGTCGTGGGTACTTGTGGCTGGTTTGATGATCATCGCTCATTCTTTCGGGCCGAGCCAATCCAACAT
TTTCAGGTTTTAGCCCATGAAACGCCCGATCAAGCAGCAGCACGGGTTGCCAGCGACATGTTGGGCTACCTCGAATACCG
AATCGCCACCCATCCTGCAAGTTGGGTTGTACTGCAATCAGTGTGGGCCAATCGCACCGACGATTAA

Upstream 100 bases:

>100_bases
GAGGGGCTGGGGGTAAGGGCATGTCATGGATTATCAATCTAATGAACCATTACACCTAAGCCCTATGCTCTATGCTCTTT
GTTCTATGCTCTAAACAATT

Downstream 100 bases:

>100_bases
AATTCGTGCTACTATTGGGCCAATTGATCCAAATTTGCCGATTTGCTGAACAACTACCAAATAAAGGAAGGCCAAGCACA
TGGCCACGATGCCAATGAGT

Product: lipid A biosynthesis acyltransferase

Products: NA

Alternate protein names: PIM acyltransferase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNTLPFFRLAMRWLPRLPNWLVDAACDLLGVGLLAIPRLRHNTRSNLKRIAPKTQGLARWYLQSRVLANSLRHYADLVRL
PAWSSEQLRQRFEHSGLEHLRQLTETGGLVIVAHTGSFSTGLSVLAAHGLPVVLVVEAIEPPEHLELVKELRAAHGGELI
VLGPNAGREVLKALRAKKLVVLAGDRDLAAQSIKLPFFGEPADVPIGPARLALRGWPVVVGTCGWFDDHRSFFRAEPIQH
FQVLAHETPDQAAARVASDMLGYLEYRIATHPASWVVLQSVWANRTDD

Sequences:

>Translated_288_residues
MNTLPFFRLAMRWLPRLPNWLVDAACDLLGVGLLAIPRLRHNTRSNLKRIAPKTQGLARWYLQSRVLANSLRHYADLVRL
PAWSSEQLRQRFEHSGLEHLRQLTETGGLVIVAHTGSFSTGLSVLAAHGLPVVLVVEAIEPPEHLELVKELRAAHGGELI
VLGPNAGREVLKALRAKKLVVLAGDRDLAAQSIKLPFFGEPADVPIGPARLALRGWPVVVGTCGWFDDHRSFFRAEPIQH
FQVLAHETPDQAAARVASDMLGYLEYRIATHPASWVVLQSVWANRTDD
>Mature_288_residues
MNTLPFFRLAMRWLPRLPNWLVDAACDLLGVGLLAIPRLRHNTRSNLKRIAPKTQGLARWYLQSRVLANSLRHYADLVRL
PAWSSEQLRQRFEHSGLEHLRQLTETGGLVIVAHTGSFSTGLSVLAAHGLPVVLVVEAIEPPEHLELVKELRAAHGGELI
VLGPNAGREVLKALRAKKLVVLAGDRDLAAQSIKLPFFGEPADVPIGPARLALRGWPVVVGTCGWFDDHRSFFRAEPIQH
FQVLAHETPDQAAARVASDMLGYLEYRIATHPASWVVLQSVWANRTDD

Specific function: Catalyzes the acylation to the position 6 of the alpha- 1,2-linked mannose residue of the phosphatidyl-myo-inositol dimannoside (PIM2) or monomannoside (PIM1) [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 32006; Mature: 32006

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLPFFRLAMRWLPRLPNWLVDAACDLLGVGLLAIPRLRHNTRSNLKRIAPKTQGLARW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YLQSRVLANSLRHYADLVRLPAWSSEQLRQRFEHSGLEHLRQLTETGGLVIVAHTGSFST
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
GLSVLAAHGLPVVLVVEAIEPPEHLELVKELRAAHGGELIVLGPNAGREVLKALRAKKLV
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCEEE
VLAGDRDLAAQSIKLPFFGEPADVPIGPARLALRGWPVVVGTCGWFDDHRSFFRAEPIQH
EEECCCCHHHHEECCCCCCCCCCCCCCHHHHHEECCCEEEEECCCCHHHHHHHHCCHHHH
FQVLAHETPDQAAARVASDMLGYLEYRIATHPASWVVLQSVWANRTDD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTLPFFRLAMRWLPRLPNWLVDAACDLLGVGLLAIPRLRHNTRSNLKRIAPKTQGLARW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YLQSRVLANSLRHYADLVRLPAWSSEQLRQRFEHSGLEHLRQLTETGGLVIVAHTGSFST
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
GLSVLAAHGLPVVLVVEAIEPPEHLELVKELRAAHGGELIVLGPNAGREVLKALRAKKLV
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCEEE
VLAGDRDLAAQSIKLPFFGEPADVPIGPARLALRGWPVVVGTCGWFDDHRSFFRAEPIQH
EEECCCCHHHHEECCCCCCCCCCCCCCHHHHHEECCCEEEEECCCCHHHHHHHHCCHHHH
FQVLAHETPDQAAARVASDMLGYLEYRIATHPASWVVLQSVWANRTDD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]