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The map label for this gene is degP [C]

Identifier: 159899744

GI number: 159899744

Start: 4083664

End: 4084875

Strand: Direct

Name: degP [C]

Synonym: Haur_3226

Alternate gene names: 159899744

Gene position: 4083664-4084875 (Clockwise)

Preceding gene: 159899742

Following gene: 159899746

Centisome position: 64.34

GC content: 50.83

Gene sequence:

>1212_bases
ATGAAGCAACGCAGCATGCGTATTTTGATTCCAGCATTTCTTATTCCACTAGGCCTTTGTATTGTGGCAAGCCTGTTGAT
TTGGATCTTCGCCCCAGCTAACGATGCTGCTGGAGAAAGCTCAAATAACGATTCAACTCTTTCAGTTGCGCCAACCACAG
CTCCAGTTAGCGCTTTGAGCGAAGCACCGGGCAATGGCTTGAGCGACGAACAAGCGCGGATCGATTTGTATAAGCGAGTT
GGCCCAGCGGTTGTCAGCATCGATACCGAAGTTACCGGTGAAGGTAGCGAGGCGGCAACTGGCGAGGCGCTTGGCTCAGG
CTTTTTGGTCGATGATCAAGGCCATATTGCTACCAACAACCATGTAATCGAAGGTGCAACCCGTATTTTCGTCACTTTTG
CTGATGGCCGCCAAGTGCCAGCCACTCTGCGCGGAACCGATGAAGATAACGATATTGCGGTGATTAAGGTTGATGCCGCA
GCCGTGAGCAAGATTGCGCCGATGGTATTTGGCAACTCACGCGAAGTTCAAGTTGGTCAAGATACGATTGCAATTGGCAA
TCCGTTTGGCTTGCAAAATACCATGACTTTGGGGATTGTGAGCGCGGTCGAAGGGCGTTCGTTGCCAGGCCGTACCCTTG
CTAATGGTGGTCAATTTCGCATCAGCCGAATTATTCAGACCGATGCGGCGATCAACCCAGGCAATAGCGGTGGGCCATTG
CTCAATAGTAAAGGCGAAGTGATTGGGATTAACACCGCGATTCGGGTGAGTGACCCAACTGCTGCACCAGCCTTTGCCGG
AGTTGGTTATGCCGTGCCCGCCAACACGGTCAAAGTGATCGTCGAAGATTTGATTAAAACTGGCAAGCACGATTCAGCCT
ATCTTGGCGTGAGCATGCTAACGATCAGCGCTCAATTGGCGCAAGAATTGAAATTACCAGTCAGCCAAGGCGCGTTGGTG
ACCAATGTAGTCGTTGATGGTCCCGCCGATCAAGCTGGAATTCGCTTGGGTACAACCAGTATCGAAGTTGATGGTGCTGC
ATTAATTATTGATAGCGACATCGTGACTGCCTTCAACGGCGAAACGATTCGCTCCAGTGACGATTTGATTGCCCATATCA
ACGATTCGCGAGTTGGCGATAAAGTCATTTTGACGATCATACGGGGTGATGAAGAGCAAACGATCGAGGTAACCTTGGGG
GCACGCCCTTAA

Upstream 100 bases:

>100_bases
CTGACCCCTGATCCCCAACCCCCACAAATAGATTTTGCGATAAAATTATAGCATGCAGCCTACACCAACTTCGGGTGATT
ATGCAGAAAGGATGGTTTGC

Downstream 100 bases:

>100_bases
AACCAGCAGGTTAGGCCTATTTTATCACCCCTTGGGGGGATCTTTCGAGAATCTGGATCAAGAGCCGTATCTTTTTTGCA
GGCTGCACGGTTTCCCTTAT

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALSEAPGNGLSDEQARIDLYKRV
GPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNNHVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAA
AVSKIAPMVFGNSREVQVGQDTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPL
LNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSMLTISAQLAQELKLPVSQGALV
TNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNGETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLG
ARP

Sequences:

>Translated_403_residues
MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALSEAPGNGLSDEQARIDLYKRV
GPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNNHVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAA
AVSKIAPMVFGNSREVQVGQDTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPL
LNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSMLTISAQLAQELKLPVSQGALV
TNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNGETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLG
ARP
>Mature_403_residues
MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALSEAPGNGLSDEQARIDLYKRV
GPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNNHVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAA
AVSKIAPMVFGNSREVQVGQDTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPL
LNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSMLTISAQLAQELKLPVSQGALV
TNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNGETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLG
ARP

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=311, Percent_Identity=34.7266881028939, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI22129776, Length=323, Percent_Identity=34.0557275541796, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24308541, Length=284, Percent_Identity=32.7464788732394, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7019477, Length=341, Percent_Identity=32.5513196480938, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1786356, Length=298, Percent_Identity=36.9127516778523, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789629, Length=345, Percent_Identity=35.3623188405797, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1789630, Length=331, Percent_Identity=34.441087613293, Blast_Score=144, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24646839, Length=313, Percent_Identity=33.5463258785943, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41661; Mature: 41661

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALS
CCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHH
EAPGNGLSDEQARIDLYKRVGPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNN
CCCCCCCCCHHHHHHHHHHCCCEEEEEECEECCCCCCCCCCHHHCCCEEEECCCCEECCC
HVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAAAVSKIAPMVFGNSREVQVGQ
EEEECEEEEEEEEECCCCCCEEECCCCCCCCEEEEEECHHHHHHHHHHEECCCCEEEECC
DTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPL
CEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
LNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSML
CCCCCCEEEEEEEEEECCCCCCCHHCCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEE
TISAQLAQELKLPVSQGALVTNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNG
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEECCEEEEECCEEEEEECCEEEEECC
ETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLGARP
CEEECCCCEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MKQRSMRILIPAFLIPLGLCIVASLLIWIFAPANDAAGESSNNDSTLSVAPTTAPVSALS
CCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHH
EAPGNGLSDEQARIDLYKRVGPAVVSIDTEVTGEGSEAATGEALGSGFLVDDQGHIATNN
CCCCCCCCCHHHHHHHHHHCCCEEEEEECEECCCCCCCCCCHHHCCCEEEECCCCEECCC
HVIEGATRIFVTFADGRQVPATLRGTDEDNDIAVIKVDAAAVSKIAPMVFGNSREVQVGQ
EEEECEEEEEEEEECCCCCCEEECCCCCCCCEEEEEECHHHHHHHHHHEECCCCEEEECC
DTIAIGNPFGLQNTMTLGIVSAVEGRSLPGRTLANGGQFRISRIIQTDAAINPGNSGGPL
CEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
LNSKGEVIGINTAIRVSDPTAAPAFAGVGYAVPANTVKVIVEDLIKTGKHDSAYLGVSML
CCCCCCEEEEEEEEEECCCCCCCHHCCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEE
TISAQLAQELKLPVSQGALVTNVVVDGPADQAGIRLGTTSIEVDGAALIIDSDIVTAFNG
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEECCEEEEECCEEEEEECCEEEEECC
ETIRSSDDLIAHINDSRVGDKVILTIIRGDEEQTIEVTLGARP
CEEECCCCEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA