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The map label for this gene is glcK [H]

Identifier: 159899706

GI number: 159899706

Start: 4033255

End: 4034211

Strand: Direct

Name: glcK [H]

Synonym: Haur_3188

Alternate gene names: 159899706

Gene position: 4033255-4034211 (Clockwise)

Preceding gene: 159899704

Following gene: 159899707

Centisome position: 63.55

GC content: 54.55

Gene sequence:

>957_bases
ATGGCATTTGCAATCGGGATTGATCTCGGGGGCACGCATTTACGTGCGGCCTTAGTTGACCGAGATGGTGAAATTCTTGC
TCATGAACGGATTCGCACCGAAGCGCATGAAGGTGCTGAAGCAGTTGTTGGTCGGATTACTCAATTAATTAACGCCATGA
TCGCTGCGGCGAATGGTGCAACAATTGTCGGCGCTGGCATCGCCGCACCTGGCCCACTCAACCCCTTTACCGGTACGGTC
ATTACCATGCCCAACTTGCCAGGTTGGGAGAACTTCCCCATCCGCGATCGAATCGCCGCCCAAGTTCCGTTTCCAGTCGT
GCTCGGCAATGATGCCAATTTGGCTGCTGTCGGCGAATGGTTATTCGGCGGTGGTCGTGGCATGCAAAATATGATTTACG
TCACGATCAGCACGGGCGTTGGTGGTGGGGTCATTTGTGATGGTCGGTTGTTGCTCGGTCACAATGGCTTTGCCGCCGAA
GTTGGTCACATGGTGCTCGACCCGCATGGCTTTGCACCCGCCACGGCCACCCCAGCTGGTTCGTGGGAAGCGCTCGCATC
AGGCACATTTTTGGCCTACCACGCTGCCGAAGCGATGCGAGCAGGCACTGCCACCGTACTTAATCAATTAACCACTCCCG
ATGCCGTCACCACCCATCATTTAGATCTGGCGGCGCAACAAGGCGATGAGTTGGCAATTCGCTTAATCGAAAATGCTGGC
TTTTGGTGTGGGATTGCCTTCGTCAATTTGCTGCATATGTTCAGCCCTGAAGCGATTTTCGTGGGCGGCGGGGTTTCCAA
CTTAGGCGATCGTTTGCTCAACCCAGCTCGCGCCGAAATTACCAAACGCGCCTTGCCCGGCTATCGCAATGTGCCAATTC
ATCAAACCAAGATGGGCGATAATCTAGGGGTGCTTGGCGCTGCTGCCTATGCATTTAGCTCAATCCAACAAGCCTAA

Upstream 100 bases:

>100_bases
ATTGATCATCTGGGTGAATGTCTATAGGCAGAAAGCCCAAAATGCCCTGTGCTATAATTGCGCAATTAAAAGATCCGCAT
GAAAGGTATTGGTTTTTCCT

Downstream 100 bases:

>100_bases
TTTTAGCATCAAGCCGCTCAGTTCCAAAGTCTCCTGACAATGCGCCTTTGGGTCTTGGCGGCTTGCCGTTTTTAGCACAA
AGGATGCCTGCATGTCGTCA

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAFAIGIDLGGTHLRAALVDRDGEILAHERIRTEAHEGAEAVVGRITQLINAMIAAANGATIVGAGIAAPGPLNPFTGTV
ITMPNLPGWENFPIRDRIAAQVPFPVVLGNDANLAAVGEWLFGGGRGMQNMIYVTISTGVGGGVICDGRLLLGHNGFAAE
VGHMVLDPHGFAPATATPAGSWEALASGTFLAYHAAEAMRAGTATVLNQLTTPDAVTTHHLDLAAQQGDELAIRLIENAG
FWCGIAFVNLLHMFSPEAIFVGGGVSNLGDRLLNPARAEITKRALPGYRNVPIHQTKMGDNLGVLGAAAYAFSSIQQA

Sequences:

>Translated_318_residues
MAFAIGIDLGGTHLRAALVDRDGEILAHERIRTEAHEGAEAVVGRITQLINAMIAAANGATIVGAGIAAPGPLNPFTGTV
ITMPNLPGWENFPIRDRIAAQVPFPVVLGNDANLAAVGEWLFGGGRGMQNMIYVTISTGVGGGVICDGRLLLGHNGFAAE
VGHMVLDPHGFAPATATPAGSWEALASGTFLAYHAAEAMRAGTATVLNQLTTPDAVTTHHLDLAAQQGDELAIRLIENAG
FWCGIAFVNLLHMFSPEAIFVGGGVSNLGDRLLNPARAEITKRALPGYRNVPIHQTKMGDNLGVLGAAAYAFSSIQQA
>Mature_317_residues
AFAIGIDLGGTHLRAALVDRDGEILAHERIRTEAHEGAEAVVGRITQLINAMIAAANGATIVGAGIAAPGPLNPFTGTVI
TMPNLPGWENFPIRDRIAAQVPFPVVLGNDANLAAVGEWLFGGGRGMQNMIYVTISTGVGGGVICDGRLLLGHNGFAAEV
GHMVLDPHGFAPATATPAGSWEALASGTFLAYHAAEAMRAGTATVLNQLTTPDAVTTHHLDLAAQQGDELAIRLIENAGF
WCGIAFVNLLHMFSPEAIFVGGGVSNLGDRLLNPARAEITKRALPGYRNVPIHQTKMGDNLGVLGAAAYAFSSIQQA

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=268, Percent_Identity=31.3432835820896, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4885285, Length=268, Percent_Identity=31.3432835820896, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI298566315, Length=268, Percent_Identity=31.3432835820896, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI298566325, Length=268, Percent_Identity=31.3432835820896, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786891, Length=313, Percent_Identity=26.1980830670927, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081733, Length=316, Percent_Identity=30.379746835443, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787878, Length=249, Percent_Identity=27.710843373494, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082230, Length=265, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33036; Mature: 32905

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFAIGIDLGGTHLRAALVDRDGEILAHERIRTEAHEGAEAVVGRITQLINAMIAAANGA
CEEEEEECCCCCEEEEEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
TIVGAGIAAPGPLNPFTGTVITMPNLPGWENFPIRDRIAAQVPFPVVLGNDANLAAVGEW
EEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHH
LFGGGRGMQNMIYVTISTGVGGGVICDGRLLLGHNGFAAEVGHMVLDPHGFAPATATPAG
HHCCCCCCCEEEEEEEECCCCCCEEECCEEEEECCCCHHHHCCEEECCCCCCCCCCCCCC
SWEALASGTFLAYHAAEAMRAGTATVLNQLTTPDAVTTHHLDLAAQQGDELAIRLIENAG
CCHHHHCCCEEEHHHHHHHHCCHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEEEEHHCCC
FWCGIAFVNLLHMFSPEAIFVGGGVSNLGDRLLNPARAEITKRALPGYRNVPIHQTKMGD
CCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCC
NLGVLGAAAYAFSSIQQA
CCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFAIGIDLGGTHLRAALVDRDGEILAHERIRTEAHEGAEAVVGRITQLINAMIAAANGA
EEEEEECCCCCEEEEEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
TIVGAGIAAPGPLNPFTGTVITMPNLPGWENFPIRDRIAAQVPFPVVLGNDANLAAVGEW
EEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEEECCCCCHHHHHHH
LFGGGRGMQNMIYVTISTGVGGGVICDGRLLLGHNGFAAEVGHMVLDPHGFAPATATPAG
HHCCCCCCCEEEEEEEECCCCCCEEECCEEEEECCCCHHHHCCEEECCCCCCCCCCCCCC
SWEALASGTFLAYHAAEAMRAGTATVLNQLTTPDAVTTHHLDLAAQQGDELAIRLIENAG
CCHHHHCCCEEEHHHHHHHHCCHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEEEEHHCCC
FWCGIAFVNLLHMFSPEAIFVGGGVSNLGDRLLNPARAEITKRALPGYRNVPIHQTKMGD
CCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCC
NLGVLGAAAYAFSSIQQA
CCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]