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The map label for this gene is plsC [H]

Identifier: 159899661

GI number: 159899661

Start: 3970671

End: 3971330

Strand: Direct

Name: plsC [H]

Synonym: Haur_3143

Alternate gene names: 159899661

Gene position: 3970671-3971330 (Clockwise)

Preceding gene: 159899660

Following gene: 159899662

Centisome position: 62.56

GC content: 51.67

Gene sequence:

>660_bases
ATGAGCCGCTTTTATCGTTTTTATCATTATCTCGCCAAAGTGCTCTTTTTTATCTTCACTCGCCGCGTGATTGTCCGAGG
TAGCCAGCATATTCCCAAGCATGGCGCGGCAATTTTGGTTTCCAACCACATTAGCTACTCCGATCCAGCCACGATTATTG
GTTATGTCAAACGTCATGTCTATTTTATGACCAAAGCCGAGATGTTTGACGGTGGGTTTATGGATTGGGTGATTACGAGA
GCCGGGGCATTTCCGGTTCGGCGTGGCGAGGCTGATCGCACGGCGTTTCGGCGGGCACTCCAATTGCTCAGCCAAGGCCA
ATGCATCGGCCTCTACCCTGAGGGCACACGCTCAACCACGCGAACCTTGCAACAAGCGCGGGCTGGCGTGGTGTTGCTGG
CGAAACAAAGCGGTGCGCCGATTATTCCAATTGCAATCACTGGCATGGAGCGGGTGTTTTTGGGCAAATTTCCATGGTTT
GGGCGGCCAACAGTTACGATTACGATCGGCGAACCACAAACCTTGGAACAACTTGCTCAAAGCAACTTGCCAATCGCCCA
CCAACGCGATTATTTGGCTGAGCAAATTATGGCCCAAGTTGCAGCTCTATTACCGCAGGCCTATGGCGGCACGAATGTTA
GCCAACTCAGCTATGAATAG

Upstream 100 bases:

>100_bases
TGTTACATTGGCTGGGAGCAACCACAACTTTTGGCGCTTGACGATTGGCTCACAAACAAAATACTATAGCAATAGCAACG
CTGATGTGGGAGGGTAATCG

Downstream 100 bases:

>100_bases
GATGGGATGTTATGCCAACCAACGTGCCTCAACTCAGTTTTAATATCAATCTCCAAGCTGATGAACGGGTCAAGTTGATC
GCCTATCGCCATTGGCTAAT

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHVYFMTKAEMFDGGFMDWVITR
AGAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTTRTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWF
GRPTVTITIGEPQTLEQLAQSNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE

Sequences:

>Translated_219_residues
MSRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHVYFMTKAEMFDGGFMDWVITR
AGAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTTRTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWF
GRPTVTITIGEPQTLEQLAQSNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE
>Mature_218_residues
SRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHVYFMTKAEMFDGGFMDWVITRA
GAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTTRTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWFG
RPTVTITIGEPQTLEQLAQSNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789201, Length=201, Percent_Identity=23.8805970149254, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 24584; Mature: 24453

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
YFMTKAEMFDGGFMDWVITRAGAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTT
HHEEHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHH
RTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWFGRPTVTITIGEPQTLEQLAQ
HHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHH
SNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure 
SRFYRFYHYLAKVLFFIFTRRVIVRGSQHIPKHGAAILVSNHISYSDPATIIGYVKRHV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
YFMTKAEMFDGGFMDWVITRAGAFPVRRGEADRTAFRRALQLLSQGQCIGLYPEGTRSTT
HHEEHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHH
RTLQQARAGVVLLAKQSGAPIIPIAITGMERVFLGKFPWFGRPTVTITIGEPQTLEQLAQ
HHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHH
SNLPIAHQRDYLAEQIMAQVAALLPQAYGGTNVSQLSYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]