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The map label for this gene is rutB [H]

Identifier: 159899643

GI number: 159899643

Start: 3943509

End: 3944150

Strand: Direct

Name: rutB [H]

Synonym: Haur_3125

Alternate gene names: 159899643

Gene position: 3943509-3944150 (Clockwise)

Preceding gene: 159899642

Following gene: 159899644

Centisome position: 62.14

GC content: 52.65

Gene sequence:

>642_bases
ATGCAGATCGATCCATCCACAACCGCACTGGTCTTGATTGAATTTCAAAACGATTTCACCTCGGAAGGCGGGGCGCTCCA
CGGTGCTGTTGCCGAAAGTATGCAAGCTACCAATATGCTGGCCAACGCGATCGAAACGGTCAAACAAGCGCGTGAAGCAG
GCGTGACGATCATTCATGCGCCAATTTCATTTGCCGAAGGCTACCGCGAAATTACCAGCCATCCCTATGGCATTCTCAAG
GGCGTGGTCGATAACAATGCCTTTCGCAAGGGCACATGGGGCGCAGAATTGGTCGATGTGCTGACCCCAGAAAGCAGCGA
TATTGTGATCGAGGGCAAGCGTGGCCTCGATACCTTCGCCAGCACCAACCTCGATTTTATTTTGCGCAGCCGTGGCTTGA
CCAACTTGGTTTTGGCGGGCTTTTTGACCAACTGCTGCGTCGAATCGACCATGCGCTCAGGCTATGAACGTGGCTACAAT
GTCATCACTTTGACCGATTGCGTGGCCGCCACCAGCGCCGAAGAGCAACAAGGCGCAATCAGCAAAGATTATCCAATGTT
CTCGCATCCCATGGATCATCAGCAATTCCTCGAAATTTTGAGCGGACGCAGTGCCATGGTTAATGCTAGTCGCGGCTACT
AA

Upstream 100 bases:

>100_bases
TGATCTTCAATTAGTTCTTTGTGATAATGGGCTTGGGCAATGTAGCTCACATCGATGCCGCCCGATCAGCGTTCTCCATT
TCAGCCACAAGGGAGATAGT

Downstream 100 bases:

>100_bases
CGATGAATCACGCAGCAGAACTTCAGGCTGAGGTTTTGGCTGCACTTCAGCGGTCGGTTCGTGGCAAGGTTCACGCCGAC
CGCTTGACATGTGCGCTGTA

Product: isochorismatase hydrolase

Products: NA

Alternate protein names: Ureidoacrylate amidohydrolase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHAPISFAEGYREITSHPYGILK
GVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFASTNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYN
VITLTDCVAATSAEEQQGAISKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY

Sequences:

>Translated_213_residues
MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHAPISFAEGYREITSHPYGILK
GVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFASTNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYN
VITLTDCVAATSAEEQQGAISKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY
>Mature_213_residues
MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHAPISFAEGYREITSHPYGILK
GVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFASTNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYN
VITLTDCVAATSAEEQQGAISKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY

Specific function: In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby rele

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family. RutB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081820, Length=216, Percent_Identity=32.8703703703704, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87081992, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019916
- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 23075; Mature: 23075

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHA
CCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
PISFAEGYREITSHPYGILKGVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFA
CHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHH
STNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYNVITLTDCVAATSAEEQQGAI
HCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCHHHCCCC
SKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY
CCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCC
>Mature Secondary Structure
MQIDPSTTALVLIEFQNDFTSEGGALHGAVAESMQATNMLANAIETVKQAREAGVTIIHA
CCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
PISFAEGYREITSHPYGILKGVVDNNAFRKGTWGAELVDVLTPESSDIVIEGKRGLDTFA
CHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHH
STNLDFILRSRGLTNLVLAGFLTNCCVESTMRSGYERGYNVITLTDCVAATSAEEQQGAI
HCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCCHHHCCCC
SKDYPMFSHPMDHQQFLEILSGRSAMVNASRGY
CCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA