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The map label for this gene is nuoH [H]

Identifier: 159899607

GI number: 159899607

Start: 3897480

End: 3898553

Strand: Direct

Name: nuoH [H]

Synonym: Haur_3088

Alternate gene names: 159899607

Gene position: 3897480-3898553 (Clockwise)

Preceding gene: 159899606

Following gene: 159899608

Centisome position: 61.41

GC content: 51.02

Gene sequence:

>1074_bases
ATGCAAGATCGCTCAGTATGGGTGATGATTATCCACGCGGTGGTATTAGCATTTGCGGCCCTGACCAGCTTTGCTTATCT
CACCTTGATGGAACGCAAAGTCTTAGCCAAGTTGCAACATCGGGTCGGCCCTAACCAGGCTGGCCCCAATGGCTACTTGC
AACCATTGGCTGATGCTGTTAAGTTGATGTTCAAAGAAGATATTATGCCATCGCTGGCCGATAAATGGGTCTTTATTATT
GCCCCAATTTTGGCCACGATTCCGGCAATTGTGATCTTCGCAGTGATTCCACTTGGCCCTGATTTGGTGGTTTTCGGCGA
ACGAATTCCTTTGGCATTCGCTAGTTTGAATATTGGCTTGCTCTATTTCTTGGCGGTAACTTCAATCGGCGTGTATGGGA
TTACCCTCGCTGGTTGGGCCTCGAATAACAAATATTCAATGCTGGGTGGGGTTCGTTCAGCCGCCCAGATGATCAGCTAT
GAATTGGCCTTTGGGCTTTCGGTGCTGGTTCCAGTGATGTTGACCGCCTCGCGCTCAGCCGATGGCCTTGGCTCGCTCGA
TTTGGTTCAAATGGTCAATGCGCAGGCTGGCACATGGCTAGGCTTTATTCCCAAGTGGTTTGTCTTTACGCCAACCGGCT
TTATTGCCTTCTTCTTGTTCTTGATTGCGGCCACCGCTGAAGTGACCCGCGCTCCCTTCGACTTGGTTGAAGCTGAACAA
GAGTTGGTCGGTGGGTATGCCACCGAATATAGCTCGATGAAGTTTGCCTTGTTCTTCATGGCCGAATATATGAAATTGAT
CGCCATGAGCGGCTTTGCAGCGACGATGTTCCTTGGTGGTTGGCGCTTGCCCTACCTCGAAGACATTGCGGGCAACTGGG
GCGCGTTGGTTGGCTTCTTGGTGATCGCCGCCAAAATCTTCTTCTTCTTGTTCTTGTCGATCTGGGTTCGCGCCAGCTTG
CCACGGATTCGCTACGACAAACTGATGGATTTTGGTTGGAAGCGCTTGTTGCCAGTTTCCTTGGCAACGGTTGCCGCAAC
CGCTGTCATCATCGTCTTGACCAACCCACTCTAA

Upstream 100 bases:

>100_bases
AGGCGTGGTAGTCGTACCTGTTGGGGTTAATAATGTCGGCTTGGTCAGCGTCGTCGAAGGTGGCGCAACGCCAGTAGCCA
TTCGACGGGAGGCCTAAGCC

Downstream 100 bases:

>100_bases
GCACAACTTGTAAATAGTTCCCTCACCCCCTAGCCCCCTCTCCCGCAAGCGCGGAGAGGGGGAATTTTGTGCTCTGCAAG
ATTTTAGCCTGCTCAAGGCT

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAVKLMFKEDIMPSLADKWVFII
APILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGLLYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISY
ELAFGLSVLVPVMLTASRSADGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQ
ELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFLVIAAKIFFFLFLSIWVRASL
PRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL

Sequences:

>Translated_357_residues
MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAVKLMFKEDIMPSLADKWVFII
APILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGLLYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISY
ELAFGLSVLVPVMLTASRSADGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQ
ELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFLVIAAKIFFFLFLSIWVRASL
PRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL
>Mature_357_residues
MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAVKLMFKEDIMPSLADKWVFII
APILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGLLYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISY
ELAFGLSVLVPVMLTASRSADGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQ
ELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFLVIAAKIFFFLFLSIWVRASL
PRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=323, Percent_Identity=35.9133126934984, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1788618, Length=343, Percent_Identity=41.9825072886297, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39083; Mature: 39083

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KLMFKEDIMPSLADKWVFIIAPILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
LYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISYELAFGLSVLVPVMLTASRSA
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQ
CCCCCHHHHHHHHCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCHHHHHHHH
VIAAKIFFFLFLSIWVRASLPRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MQDRSVWVMIIHAVVLAFAALTSFAYLTLMERKVLAKLQHRVGPNQAGPNGYLQPLADAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KLMFKEDIMPSLADKWVFIIAPILATIPAIVIFAVIPLGPDLVVFGERIPLAFASLNIGL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
LYFLAVTSIGVYGITLAGWASNNKYSMLGGVRSAAQMISYELAFGLSVLVPVMLTASRSA
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DGLGSLDLVQMVNAQAGTWLGFIPKWFVFTPTGFIAFFLFLIAATAEVTRAPFDLVEAEQ
CCCCCHHHHHHHHCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ELVGGYATEYSSMKFALFFMAEYMKLIAMSGFAATMFLGGWRLPYLEDIAGNWGALVGFL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHCCCHHHHHHHH
VIAAKIFFFLFLSIWVRASLPRIRYDKLMDFGWKRLLPVSLATVAATAVIIVLTNPL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA