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The map label for this gene is luxQ [H]

Identifier: 159899539

GI number: 159899539

Start: 3814273

End: 3816168

Strand: Direct

Name: luxQ [H]

Synonym: Haur_3020

Alternate gene names: 159899539

Gene position: 3814273-3816168 (Clockwise)

Preceding gene: 159899536

Following gene: 159899540

Centisome position: 60.1

GC content: 49.63

Gene sequence:

>1896_bases
ATGCATTATCTTTTCGATCATCCAACATGTATTCGGCGTACATCGCCTCAACATTTAGCAAGTTATGCCTATGGCGTGCG
GGCAAGCTGCTCGGTGCGCCATCCGGCTGGCGATGGAGTCGATGACCCACGCTTTTTATTATTTGGCCCCCAACGTGGCA
ATTATCGCCATTGGTTCGATACCTATGAAATTAAGCCCGATAATGCGCCCGATTGGTATGCCCTGACCTTTCCCAAGCCT
ACCAAATTAAATGTGGTTTATTGGATGCATGGCCCCATGTTTGATGATCATGGTTGGTGGACTTCGCTCCAGGTCGAATA
TCGCGATGCTGAGGGCGCTTGGCATAAAGTTGACGATTTGCAGATCACGCCGAATTACCATTTTAGCCCGCAACGCGGCG
ATCGTAAGCCCTTCAGTGCTTATGCTGCTCATTTCAATCCAGTGCGAACCAGCGCGATTCGACTGATCGGCCAGCCCAGC
GGCAAGCCGCAAATTACGACCATGGCCTATCTTGCCGCCGATTGGAGCACTTGCGAAGGCATCGCCGCCCACTTGCGCCA
TATTCAGCAACCATTGCCCGCTATTTTTGATCTGTTACCAGCCAATACCTTGTGGGATACCTTGGCCAGCCTGCGTGATT
TAACCAAAATTGCCTTTGATCTACAAACCAGCGCGGGCTTGGGACTTGACCACTTCTTGGAGCCACAGCATTATCAACGG
TTTCACGAAAGCCAGCGTCAATGCTTCGCTGATGATTCGCTCTATCAATTAATTGGTCAGCATGCTGGTTGGCGCAAGCT
GGGCCAAACCATCGAGCAAGCTCGCGAACAAGCCTATGAAACCAAACAACCAGTCATCGCCCAACATCATGGTGGTTTGG
TCTGGCTGGTCGTGCCAGTCATTAGCAATGATCACGTTTTAGGCACAATCGAAAATCGCAATTTTATCGCCCAAGAGCCA
ATCGATTGGCAATGGCATCGTTGTTATGCCCAAGAATTGGGGCTGGATTGGGAGCGTTATCGCACGGCGTTGGAGCAAAT
TAGCACATTCAGTCAACAACAAATCAATGCCACAATCAATCATGTGCAGCAGCTGGTACGCCTAGCTCAACAATTGCTCA
AAGATAGCCAAGAAATTCATACGCTGAAAAGTAGCGCCTTGGCTGCCGAGGTGTTTAGTCGCTCCAAAAGCACCTTTATG
AGCATGATGAGCCATGAATTACGCACCCCGCTGAATGCCATTATTGGCTATAGCGAGCTGCTCATCGACGATCTGAGCGC
AACCAACCAACAACAATCGACTGATGATGCCCGCCAAATTCGCAGCGCAGGTCGCCATTTACTGCATGTGATCGAAACAA
TTTTGCAGGTATCCAACTTAGAATCAGGCGCATCAAATGTACATTACGACGATGTTGATCTTGAAATGCTGACCAATTCG
TTGGAACTTAGTTTGCGCACCCAATTTCAAAAACGCAGCAATCAACTTGAAATTAAGATCGATCCTAATGCCTCGTGGGT
CTATTCAGATAGCTCGAAAGTGCGTCAGATTATCTTCCAACTGCTGAATAATGCCAATAAATTTACCGATCATGGTCAAG
TGCGGCTAACGATTGCCCCTGATAGCCTTGACCCAGAGATGCTCGCATTCGAGGTTTGCGACACAGGTATTGGCATCGAT
CATGAGCATTTGCCGCTCTTATTTGCTGAATTCAGCCAACTTGATGCCTCAAGCACTCGCCGCTATGATGGCACAGGTAT
GGGCTTGGCGCTTTGTCGCCACTTGGCGCGGCTGCTTGGCGGCGATATTCGGGTTTGGAGCGAGCCTGGCATTGGCTCGA
CCTTTACCCTCGCCATCCCACGTCAAAGCGTGATGACTCCAGTTAACGACCTCTGA

Upstream 100 bases:

>100_bases
CCCACCCTACAGTCGGGACTAAGGTATTAGCAAAATCAATTCTATCAGCCATCGTAGCTGAGTACAATAGATGCATCATG
GGCATTTGGGAGGGCCTGCT

Downstream 100 bases:

>100_bases
TCATTTAGTAAAACAGTGCTATGCTATAAGGCGCAACGGGGCTACACGGAAGGATGTAGCCCTGTCATTATGCGTGGTTC
CTAAGGAGGGCTTGTGGAAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MHYLFDHPTCIRRTSPQHLASYAYGVRASCSVRHPAGDGVDDPRFLLFGPQRGNYRHWFDTYEIKPDNAPDWYALTFPKP
TKLNVVYWMHGPMFDDHGWWTSLQVEYRDAEGAWHKVDDLQITPNYHFSPQRGDRKPFSAYAAHFNPVRTSAIRLIGQPS
GKPQITTMAYLAADWSTCEGIAAHLRHIQQPLPAIFDLLPANTLWDTLASLRDLTKIAFDLQTSAGLGLDHFLEPQHYQR
FHESQRQCFADDSLYQLIGQHAGWRKLGQTIEQAREQAYETKQPVIAQHHGGLVWLVVPVISNDHVLGTIENRNFIAQEP
IDWQWHRCYAQELGLDWERYRTALEQISTFSQQQINATINHVQQLVRLAQQLLKDSQEIHTLKSSALAAEVFSRSKSTFM
SMMSHELRTPLNAIIGYSELLIDDLSATNQQQSTDDARQIRSAGRHLLHVIETILQVSNLESGASNVHYDDVDLEMLTNS
LELSLRTQFQKRSNQLEIKIDPNASWVYSDSSKVRQIIFQLLNNANKFTDHGQVRLTIAPDSLDPEMLAFEVCDTGIGID
HEHLPLLFAEFSQLDASSTRRYDGTGMGLALCRHLARLLGGDIRVWSEPGIGSTFTLAIPRQSVMTPVNDL

Sequences:

>Translated_631_residues
MHYLFDHPTCIRRTSPQHLASYAYGVRASCSVRHPAGDGVDDPRFLLFGPQRGNYRHWFDTYEIKPDNAPDWYALTFPKP
TKLNVVYWMHGPMFDDHGWWTSLQVEYRDAEGAWHKVDDLQITPNYHFSPQRGDRKPFSAYAAHFNPVRTSAIRLIGQPS
GKPQITTMAYLAADWSTCEGIAAHLRHIQQPLPAIFDLLPANTLWDTLASLRDLTKIAFDLQTSAGLGLDHFLEPQHYQR
FHESQRQCFADDSLYQLIGQHAGWRKLGQTIEQAREQAYETKQPVIAQHHGGLVWLVVPVISNDHVLGTIENRNFIAQEP
IDWQWHRCYAQELGLDWERYRTALEQISTFSQQQINATINHVQQLVRLAQQLLKDSQEIHTLKSSALAAEVFSRSKSTFM
SMMSHELRTPLNAIIGYSELLIDDLSATNQQQSTDDARQIRSAGRHLLHVIETILQVSNLESGASNVHYDDVDLEMLTNS
LELSLRTQFQKRSNQLEIKIDPNASWVYSDSSKVRQIIFQLLNNANKFTDHGQVRLTIAPDSLDPEMLAFEVCDTGIGID
HEHLPLLFAEFSQLDASSTRRYDGTGMGLALCRHLARLLGGDIRVWSEPGIGSTFTLAIPRQSVMTPVNDL
>Mature_631_residues
MHYLFDHPTCIRRTSPQHLASYAYGVRASCSVRHPAGDGVDDPRFLLFGPQRGNYRHWFDTYEIKPDNAPDWYALTFPKP
TKLNVVYWMHGPMFDDHGWWTSLQVEYRDAEGAWHKVDDLQITPNYHFSPQRGDRKPFSAYAAHFNPVRTSAIRLIGQPS
GKPQITTMAYLAADWSTCEGIAAHLRHIQQPLPAIFDLLPANTLWDTLASLRDLTKIAFDLQTSAGLGLDHFLEPQHYQR
FHESQRQCFADDSLYQLIGQHAGWRKLGQTIEQAREQAYETKQPVIAQHHGGLVWLVVPVISNDHVLGTIENRNFIAQEP
IDWQWHRCYAQELGLDWERYRTALEQISTFSQQQINATINHVQQLVRLAQQLLKDSQEIHTLKSSALAAEVFSRSKSTFM
SMMSHELRTPLNAIIGYSELLIDDLSATNQQQSTDDARQIRSAGRHLLHVIETILQVSNLESGASNVHYDDVDLEMLTNS
LELSLRTQFQKRSNQLEIKIDPNASWVYSDSSKVRQIIFQLLNNANKFTDHGQVRLTIAPDSLDPEMLAFEVCDTGIGID
HEHLPLLFAEFSQLDASSTRRYDGTGMGLALCRHLARLLGGDIRVWSEPGIGSTFTLAIPRQSVMTPVNDL

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=38.0566801619433, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=34.8148148148148, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=34.5679012345679, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=32.8063241106719, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=35.0649350649351, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786600, Length=376, Percent_Identity=25.2659574468085, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=268, Percent_Identity=25, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=26, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=229, Percent_Identity=29.2576419213974, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786783, Length=289, Percent_Identity=22.4913494809689, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=26.8722466960352, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=23.7668161434978, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=41.8918918918919, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71826; Mature: 71826

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYLFDHPTCIRRTSPQHLASYAYGVRASCSVRHPAGDGVDDPRFLLFGPQRGNYRHWFD
CCCCCCCCHHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCE
TYEIKPDNAPDWYALTFPKPTKLNVVYWMHGPMFDDHGWWTSLQVEYRDAEGAWHKVDDL
EEEECCCCCCCEEEEECCCCCEEEEEEEECCCEECCCCCEEEEEEEEECCCCCCEECCCE
QITPNYHFSPQRGDRKPFSAYAAHFNPVRTSAIRLIGQPSGKPQITTMAYLAADWSTCEG
EECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHEEECCCCCCCEEEEEEECCCCHHHHH
IAAHLRHIQQPLPAIFDLLPANTLWDTLASLRDLTKIAFDLQTSAGLGLDHFLEPQHYQR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHH
FHESQRQCFADDSLYQLIGQHAGWRKLGQTIEQAREQAYETKQPVIAQHHGGLVWLVVPV
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEE
ISNDHVLGTIENRNFIAQEPIDWQWHRCYAQELGLDWERYRTALEQISTFSQQQINATIN
ECCCEEEEEECCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HVQQLVRLAQQLLKDSQEIHTLKSSALAAEVFSRSKSTFMSMMSHELRTPLNAIIGYSEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIDDLSATNQQQSTDDARQIRSAGRHLLHVIETILQVSNLESGASNVHYDDVDLEMLTNS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LELSLRTQFQKRSNQLEIKIDPNASWVYSDSSKVRQIIFQLLNNANKFTDHGQVRLTIAP
HHHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
DSLDPEMLAFEVCDTGIGIDHEHLPLLFAEFSQLDASSTRRYDGTGMGLALCRHLARLLG
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
GDIRVWSEPGIGSTFTLAIPRQSVMTPVNDL
CCEEEECCCCCCCEEEEECCCHHHCCCCCCC
>Mature Secondary Structure
MHYLFDHPTCIRRTSPQHLASYAYGVRASCSVRHPAGDGVDDPRFLLFGPQRGNYRHWFD
CCCCCCCCHHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCE
TYEIKPDNAPDWYALTFPKPTKLNVVYWMHGPMFDDHGWWTSLQVEYRDAEGAWHKVDDL
EEEECCCCCCCEEEEECCCCCEEEEEEEECCCEECCCCCEEEEEEEEECCCCCCEECCCE
QITPNYHFSPQRGDRKPFSAYAAHFNPVRTSAIRLIGQPSGKPQITTMAYLAADWSTCEG
EECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHEEECCCCCCCEEEEEEECCCCHHHHH
IAAHLRHIQQPLPAIFDLLPANTLWDTLASLRDLTKIAFDLQTSAGLGLDHFLEPQHYQR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHH
FHESQRQCFADDSLYQLIGQHAGWRKLGQTIEQAREQAYETKQPVIAQHHGGLVWLVVPV
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEEE
ISNDHVLGTIENRNFIAQEPIDWQWHRCYAQELGLDWERYRTALEQISTFSQQQINATIN
ECCCEEEEEECCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HVQQLVRLAQQLLKDSQEIHTLKSSALAAEVFSRSKSTFMSMMSHELRTPLNAIIGYSEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIDDLSATNQQQSTDDARQIRSAGRHLLHVIETILQVSNLESGASNVHYDDVDLEMLTNS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LELSLRTQFQKRSNQLEIKIDPNASWVYSDSSKVRQIIFQLLNNANKFTDHGQVRLTIAP
HHHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
DSLDPEMLAFEVCDTGIGIDHEHLPLLFAEFSQLDASSTRRYDGTGMGLALCRHLARLLG
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
GDIRVWSEPGIGSTFTLAIPRQSVMTPVNDL
CCEEEECCCCCCCEEEEECCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]