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The map label for this gene is rsbRA [H]

Identifier: 159899535

GI number: 159899535

Start: 3809624

End: 3811156

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_3016

Alternate gene names: 159899535

Gene position: 3809624-3811156 (Clockwise)

Preceding gene: 159899530

Following gene: 159899536

Centisome position: 60.03

GC content: 49.25

Gene sequence:

>1533_bases
ATGACATCTGCGCCATCAACTGGCACGACCTCGCTGCGTCGCCAAACCAAAATTGTGCTAGGAGCCAGCCTCGTGCTGCT
GGTAGCGGTACTCATTTTTCCGCTGCGTATCTTGTTGCTCCAATCGTTTGCCGAGCTAGAAACAACCTCAATGCAAACCG
ACCTTGATCGGGTGTTGAATGCTTTGCAGTTTGAGCAAAATCGCCTCGACACGGCCTTGGTTTCATGGTCAACCTGGGAT
GATACGTATGCCTTTATCGAGGCTCCCGATGCTGATTACATTAGCAACAATGCTGGCGATGATGTTTTCGCGACCTATAA
ATTTAATATTATGGCCTTTCTCAACCAGCAACAAGCCTTGGTGTATGGACGAATGGCCGAGGCAGATACATTTAATGATT
TACCAGCAAACTTTTTGCCATTTGTGCAGCAAATTCCGCAACTAACGACGTTTAGTGACCCCAGCCAACGTAATTTAGGC
ATTGTACGTTTTCAAGAGCGCATTGTCTTGGTTGCTGCCCGCCCGATTATTGATAGCCAAGGCCAAGGGCCAATTCGCGG
CACAGTGATTTTTGGGCGCTATCTTGATCAACAGGTGCTTAATGATTTAGCTGCGGTCACTCTATTTCCTTTCAGCTTGG
AAGATGTGCTGAATCCACCAAGCGATCTGACAAGCAGCATTCAGCAATTGAGTGATGTCAATCCCCGCCAAATCATCCCA
ATCGATGAGCATGCCTTGCGTGGCTTACAGCAAATCAACGATCTCCAAGGCAACCCAGCCCTGATTATCAACATTATTCG
GCCACGCACAATCTACAACCAAGGCCATCATGCCTTGCAGTTTGTAGTAATTTTGACCTTTCTGGTAACCGCAGTTGGTG
GCTTTGTGTTGTACTTTTTGCTCAATCGAGTGGTCATCAGCCGTGTGTTGCGCTTGAGCAGCGAAATCAAACACGTTGCC
AATAATCTGAATGAACGGGTAGCAGTGGTGGGCAACGATGAGGTTGCGGGTTTGGCGACCAGCATTAATCAAACCTTGAA
TGTGCTCGAACAAGCGCAACGAGCAACCGCAGCCGCTGAAGCCGAGCGCAACCAACTGCAAGCGAATACCCTGGCAGCCC
AAACTGAACAACTAGCACTCCAAGAGCAATTAATCAAAGCCCAAGAATTTGTAATCGCCGAACAAGCTACACCGTTGATT
CCCTTCCGCGATGATATGTTGGTGATGCCCTTGGTCGGCGCGATCGATCAGGCACGGGCTAACCACATTTTGGGCACATT
ATTGCAAGGAGTTGAGCAACAACGCGCTCGGATCGCGATCATCGATATTACTGGAGTCGCTCAAATTGATGGCTTTACCG
CCGAAATGTTGCTCAAGGCCGCCAAGGCTGTGCGCTTGCTTGGTGCTCAATTGGTGCTAACCGGCCTCAGCCCAGAGATT
GCTCAATCGTTAGTTGCCTTCGGCCAGCAGTTGAACCAACTTACTACATTTAGCAGCTTGCAGGCAGGCATTGCTTGGAG
TATTCGGCGCTAA

Upstream 100 bases:

>100_bases
GGTTTAATCTGGGTCAAGTAACCTATCCCAACCAAGCAGAGAACGTGCTATCATAGGCGCACAATTCTACCCAGCCAATC
TAGATAGGTTGCATCGTATT

Downstream 100 bases:

>100_bases
ATTCGCTCTTCTCAACCAATTTTGGCCATGCTATGATGGGGAACAGTGTTGTTCCCCATTATTAATGCTTGCCCCAAGCC
AACCAAGGAGCAGAAACATG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLNALQFEQNRLDTALVSWSTWD
DTYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQALVYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLG
IVRFQERIVLVAARPIIDSQGQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIP
IDEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFLLNRVVISRVLRLSSEIKHVA
NNLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAEAERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLI
PFRDDMLVMPLVGAIDQARANHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEI
AQSLVAFGQQLNQLTTFSSLQAGIAWSIRR

Sequences:

>Translated_510_residues
MTSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLNALQFEQNRLDTALVSWSTWD
DTYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQALVYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLG
IVRFQERIVLVAARPIIDSQGQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIP
IDEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFLLNRVVISRVLRLSSEIKHVA
NNLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAEAERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLI
PFRDDMLVMPLVGAIDQARANHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEI
AQSLVAFGQQLNQLTTFSSLQAGIAWSIRR
>Mature_509_residues
TSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLNALQFEQNRLDTALVSWSTWDD
TYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQALVYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLGI
VRFQERIVLVAARPIIDSQGQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIPI
DEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFLLNRVVISRVLRLSSEIKHVAN
NLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAEAERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLIP
FRDDMLVMPLVGAIDQARANHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEIA
QSLVAFGQQLNQLTTFSSLQAGIAWSIRR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG3322

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 56111; Mature: 55980

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50885 HAMP ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQFEQNRLDTALVSWSTWDDTYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQAL
HHHHHHHHHHHHHEEECCCCCCEEEEECCCCCHHCCCCCCCEEEEEEEEEHHHHCCHHHH
VYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLGIVRFQERIVLVAARPIIDSQ
HHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECEEEEEEECCCCCCC
GQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEC
IDEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFL
CCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNRVVISRVLRLSSEIKHVANNLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLIPFRDDMLVMPLVGAIDQARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHH
NHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEI
HHHHHHHHHHHHHHCCEEEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHH
AQSLVAFGQQLNQLTTFSSLQAGIAWSIRR
HHHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure 
TSAPSTGTTSLRRQTKIVLGASLVLLVAVLIFPLRILLLQSFAELETTSMQTDLDRVLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQFEQNRLDTALVSWSTWDDTYAFIEAPDADYISNNAGDDVFATYKFNIMAFLNQQQAL
HHHHHHHHHHHHHEEECCCCCCEEEEECCCCCHHCCCCCCCEEEEEEEEEHHHHCCHHHH
VYGRMAEADTFNDLPANFLPFVQQIPQLTTFSDPSQRNLGIVRFQERIVLVAARPIIDSQ
HHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECEEEEEEECCCCCCC
GQGPIRGTVIFGRYLDQQVLNDLAAVTLFPFSLEDVLNPPSDLTSSIQQLSDVNPRQIIP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEC
IDEHALRGLQQINDLQGNPALIINIIRPRTIYNQGHHALQFVVILTFLVTAVGGFVLYFL
CCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNRVVISRVLRLSSEIKHVANNLNERVAVVGNDEVAGLATSINQTLNVLEQAQRATAAAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AERNQLQANTLAAQTEQLALQEQLIKAQEFVIAEQATPLIPFRDDMLVMPLVGAIDQARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHH
NHILGTLLQGVEQQRARIAIIDITGVAQIDGFTAEMLLKAAKAVRLLGAQLVLTGLSPEI
HHHHHHHHHHHHHHCCEEEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHH
AQSLVAFGQQLNQLTTFSSLQAGIAWSIRR
HHHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]