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The map label for this gene is cysH [H]

Identifier: 159898273

GI number: 159898273

Start: 2036187

End: 2036891

Strand: Reverse

Name: cysH [H]

Synonym: Haur_1749

Alternate gene names: 159898273

Gene position: 2036891-2036187 (Counterclockwise)

Preceding gene: 159898279

Following gene: 159898272

Centisome position: 32.09

GC content: 52.48

Gene sequence:

>705_bases
ATGGTCATGCACGCAACCCTGCCAAGCCGCGAGGCTCTGACAGCACTCGATACTCAATTAACGAGCCAAACTCCTCAAGC
AATTGTGCGTTGGGCGATCGATCACTATTTTCCCAATCTAGCCCTGACGTGTTCGTTTGGCGGTTCATCTGGCATGGTGT
TGCTCGATATTGCGCTCAAACTTGAGCCAAATTTGCCAGTGCTGGTGCTCGACACAGGCTTGCTGTTCAGCGAAACCTAC
GCCTTGGTTGAGCAAATTGAAAAGCATTATGGTATTACAGTGCAATATTCACGCCCACGCCAAACTGTGGCTGAACAAGC
CGCTACCCACGGCCCCGAACTTTGGGGCACGAACCCCGATTTGTGCTGCAAACTACGCAAGGTTGAGCCGCTCAAAGATG
TGCTGGCTCCCTACGATGCTTGGTTAACCGCGCTGCGTCGCGACCAAAGCAGCACGCGGGCAAATACTCCAGTGGTTTCT
TGGAATGAAAAACATCAACTGGTTAAAATTTGCCCCTTAGCCTTGTGGACTGAGCGCGATATTTGGCGCTACATCCATGC
CAATGGTGTGCCCTATAACCCATTGCTCGATCAAGGCTACACCAGCCTCGGATGTCACACTTGTACAAGCCACCCGGTGA
ACGGTGACCCACGCAGCGGACGCTGGGCTGGCTTTAACAAAACCGAGTGTGGACTCCATATCTAA

Upstream 100 bases:

>100_bases
CTAATTCCGACAGTGATGTCTGACAGATGAGCAGTAGCCCGTGACAGTCATGCCACGATCTCTACTCCTCGTCTGCCCAA
TATACAGATGAGGTTTTTTT

Downstream 100 bases:

>100_bases
AATTCCATTTGTTCGTTATGTTATGTGTAATCAATGTTGATTAGCATAAAGGTGCCACTTTATGCTAGCTGCTATTCTAT
GTTCGAGGGTGTGCTTCAAT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALKLEPNLPVLVLDTGLLFSETY
ALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPDLCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVS
WNEKHQLVKICPLALWTERDIWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI

Sequences:

>Translated_234_residues
MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALKLEPNLPVLVLDTGLLFSETY
ALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPDLCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVS
WNEKHQLVKICPLALWTERDIWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI
>Mature_234_residues
MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALKLEPNLPVLVLDTGLLFSETY
ALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPDLCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVS
WNEKHQLVKICPLALWTERDIWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=228, Percent_Identity=32.4561403508772, Blast_Score=119, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325425, Length=238, Percent_Identity=36.1344537815126, Blast_Score=124, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26146; Mature: 26146

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALK
CEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEE
LEPNLPVLVLDTGLLFSETYALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPD
ECCCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCHH
LCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVSWNEKHQLVKICPLALWTERD
HEEEECCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEHHHHHHCCCHH
IWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI
HHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVMHATLPSREALTALDTQLTSQTPQAIVRWAIDHYFPNLALTCSFGGSSGMVLLDIALK
CEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEE
LEPNLPVLVLDTGLLFSETYALVEQIEKHYGITVQYSRPRQTVAEQAATHGPELWGTNPD
ECCCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCHH
LCCKLRKVEPLKDVLAPYDAWLTALRRDQSSTRANTPVVSWNEKHQLVKICPLALWTERD
HEEEECCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEHHHHHHCCCHH
IWRYIHANGVPYNPLLDQGYTSLGCHTCTSHPVNGDPRSGRWAGFNKTECGLHI
HHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA