Click here to switch to the map view.

The map label for this gene is cbhA [H]

Identifier: 159898190

GI number: 159898190

Start: 1933604

End: 1934971

Strand: Reverse

Name: cbhA [H]

Synonym: Haur_1666

Alternate gene names: 159898190

Gene position: 1934971-1933604 (Counterclockwise)

Preceding gene: 159898191

Following gene: 159898189

Centisome position: 30.49

GC content: 50.44

Gene sequence:

>1368_bases
ATGATGGTGAATCCAAAACGGGGATGGCGTTTATTAATGATTATGCTGATGCTTGGATTGGTTTGGACACAGAGCCAAAA
ACCAGCCCAAGCGCAAACGAGCAGTGCTTGTTCGATTAGCTATAGCATTGTTGGGCAGTGGCAAGGTGGTTTTCAGGGCG
ATATCGCGATTCGTAACACTGGCACAAGCCCAATCAACAATTGGACATTAACTTGGAGTTTCAATAATCAAGCTATTTCA
CAATTATGGGGTGGCAATTATAGCCAAACAAACAATGCCGTCAGTGTTAGCAATATGGCTTGGAATGGCACAATTGCCAG
CAACTCCAGCGTAAGTTTGGGCTTTATTGCTAGCTGGACAGGCAGCAATCCAATTCCTAGCCATTTTCAGGTGAATGGTA
TCGCCTGCAATGGCGGCATTACACCAACCGCGACCGGCGTTGTGCCAACTGCCACCCGCACACCAATGCCGAGCACTGCA
ACCGCAATTCCCACAGCAACCCGCACGCCTGCGCCTTCAGCCACAACAGTTGTGCCAACCGCAACCCGCACGCCTGCGCC
AACCGCAACTCGCACACCTGCACCGACTGCAACTCGCACGCCAACCGTTACGCCAACGGGCTGGAATCCGCCAAGCAATT
TGGTAACACCACTGAATGAAGTTTGGCAGCATGTCGAATCGACCTATGGCAATTTGTATGGTTTTCGCAATTACGGCTGG
GATCAAGTGATTGCAGGCAATGGCTCGATTAATTATTGTGTACGCTGGGATTCGGATGCTCCAGTTTCCGCCGCCTTGCG
CGACCAAATTCATGCCTCGCTGGCGCGACAATTCAAAAAATGGATGGATGCGATGCTTGATAATGGTCAAGGCACCAACG
GCTGGCCTTACACCAATGTCAATATCAAAGTGGTTGGCTGGGCCGTGCGCGATCGCAGCACCCTGCAATGGAGCGATAAC
TCAGTTGATATTTATGTCAATAATATCGCTGAAAATGCACCGCAATGTGCTCCGCCATGTGGCCGTTTCTTCAACCAAGA
TGGCGATTATTCCGATTGTCCTGGCGGCTTCGATCACCACTACGATATGTCGTTGTGGCTGACCAAGGGTATGGCTGGCG
GCGCTGGGGGCGATTGGGGTCAGCGGGTTGGCAGCGAATATTTCGTCAACAACCTCAACAGCGAGAATATTCACATCTTT
CTGCATGAAGTTGGCCATACCTTTGGGCTTGACGATTTTTACGATTGGACACCGACTGGCATCAACAGCTTTATTATGAA
TGCTGGCAGCGCTAGCCAAATTACTGAGTTTGATAAATGGATGTTGCGCGACTTCTGGCGACATCTCAAGAGCCGCTACG
GCTACTAA

Upstream 100 bases:

>100_bases
TGGCCTAACCAAGGTTGAATCGATGACCGATTGTTTTGTTCTTGCTTGGGATCGATTCCAAATCATCCTTGGAATTGTTC
AGCTGTGGTTAGGAGTACCA

Downstream 100 bases:

>100_bases
ATTCGCTGCACACCTCACGCCAACGGCCAGCCTCGCGCTGGTCGTTCCTTTTTTAGCGCTTGACAAACTGAGTATATGCT
GTATATACTGTATATATGAA

Product: cellulose-binding family II protein

Products: NA

Alternate protein names: 1,4-beta-cellobiohydrolase A; CBP95; Exocellobiohydrolase A [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNTGTSPINNWTLTWSFNNQAIS
QLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWTGSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTA
TAIPTATRTPAPSATTVVPTATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGW
DQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNVNIKVVGWAVRDRSTLQWSDN
SVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHHYDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIF
LHEVGHTFGLDDFYDWTPTGINSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY

Sequences:

>Translated_455_residues
MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNTGTSPINNWTLTWSFNNQAIS
QLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWTGSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTA
TAIPTATRTPAPSATTVVPTATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGW
DQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNVNIKVVGWAVRDRSTLQWSDN
SVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHHYDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIF
LHEVGHTFGLDDFYDWTPTGINSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY
>Mature_455_residues
MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNTGTSPINNWTLTWSFNNQAIS
QLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWTGSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTA
TAIPTATRTPAPSATTVVPTATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGW
DQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNVNIKVVGWAVRDRSTLQWSDN
SVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHHYDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIF
LHEVGHTFGLDDFYDWTPTGINSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY

Specific function: This enzyme hydrolyzes 1,4-beta-D-glucosidic linkages of cellulose. Weak activity against carboxymethylcellulose, bacterial microcrystalline cellulose and barley beta-glucan. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 fibronectin type-III domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016288
- InterPro:   IPR008965
- InterPro:   IPR012291
- InterPro:   IPR018366
- InterPro:   IPR001919
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001524
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00553 CBM_2; PF00041 fn3; PF01341 Glyco_hydro_6 [H]

EC number: =3.2.1.91 [H]

Molecular weight: Translated: 49835; Mature: 49835

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCEEEEEC
GTSPINNWTLTWSFNNQAISQLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWT
CCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCEEEECCEEECCEECCCCCEEEEEEEECC
GSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTATAIPTATRTPAPSATTVVPT
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
ATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCC
DQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNV
CEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
NIKVVGWAVRDRSTLQWSDNSVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHH
EEEEEEEEECCCCEEEECCCCEEEEEECHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
YDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIFLHEVGHTFGLDDFYDWTPTG
CCEEEEEECCCCCCCCCHHHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
INSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMVNPKRGWRLLMIMLMLGLVWTQSQKPAQAQTSSACSISYSIVGQWQGGFQGDIAIRNT
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCEEEEEC
GTSPINNWTLTWSFNNQAISQLWGGNYSQTNNAVSVSNMAWNGTIASNSSVSLGFIASWT
CCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCEEEECCEEECCEECCCCCEEEEEEEECC
GSNPIPSHFQVNGIACNGGITPTATGVVPTATRTPMPSTATAIPTATRTPAPSATTVVPT
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
ATRTPAPTATRTPAPTATRTPTVTPTGWNPPSNLVTPLNEVWQHVESTYGNLYGFRNYGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCC
DQVIAGNGSINYCVRWDSDAPVSAALRDQIHASLARQFKKWMDAMLDNGQGTNGWPYTNV
CEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
NIKVVGWAVRDRSTLQWSDNSVDIYVNNIAENAPQCAPPCGRFFNQDGDYSDCPGGFDHH
EEEEEEEEECCCCEEEECCCCEEEEEECHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
YDMSLWLTKGMAGGAGGDWGQRVGSEYFVNNLNSENIHIFLHEVGHTFGLDDFYDWTPTG
CCEEEEEECCCCCCCCCHHHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
INSFIMNAGSASQITEFDKWMLRDFWRHLKSRYGY
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8065260; 8458833 [H]