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The map label for this gene is baeB [H]

Identifier: 159898167

GI number: 159898167

Start: 1900091

End: 1901485

Strand: Reverse

Name: baeB [H]

Synonym: Haur_1643

Alternate gene names: 159898167

Gene position: 1901485-1900091 (Counterclockwise)

Preceding gene: 159898171

Following gene: 159898166

Centisome position: 29.96

GC content: 52.62

Gene sequence:

>1395_bases
ATGTTTTTCCAACGGTTGTATCACGATGGTTTAGCCCAAGCAAGTTATTTAGTCGGTTGCCAAAAAACTGGCGAAGCTTT
GGTCATTGATCCCCATCGTGATAGTGCAGTGTATTTGAATGCAGCGCAAGCGGCTGGTTTGCGGATTAGCGCAATCACCG
AAACCCATATTCACGCCGATTTTGTCTCGGGCAGCCGCGAGCTGGCGCAAATTACGGGCGCAAAACTGTATCTTTCGGCA
GCAGGCACAGCAGCTTGGCAATATGCTTTTGCCAGCAGCAACCCCAATGTGCAGTTGATCAACGATGGCGATAGCTGGAT
GGTTGGCAATTTGAAGATCGAGGTCTTGCATACCCCAGGCCATACGCCAGAACATGTGATTTTTATGCTCACCGACACGC
CTGCTGGCGATGAACCAATGGGTATTTTCACAGGCGATTTGTTGTTTGCTGGCGATGTTGGCCGCCCTGACTTGCTCGAA
AAAGCCGCTGGGATTCAAGGCACCAGCGAGGCCGGAGCCAAAGATTTGTTTAAATCGTTGCAGCGCATCGCTTCCTTGCC
CGATTTCTTGCAAGTTTGGCCAGGCCATGGTTCGGGCAGCGCTTGTGGCAAAGCACTGGGAGCTGTGCCGCAAAGTACCT
TGGGCTACGAAAAGAAAGTTAATTGGGCCTTCAAACAGCAGAACGAGGCTGATTTTGTGGCCGCAGTGCTCGATGGTCAG
CCAACGCCACCGCCCTATTTCGCCGCGATGAAGCGCATCAACCGCGATGGTCCTGAGTTGCGCCCGCAACGTTTGCCAGC
CCTCAGCCTTGCCGAAATTAAGCTTGATAATCGGTTGGTTGTTGATTTACGTTCGGCCAATGATTTTGCTCAAGCCAGCA
TTCCAGGCGCACTCAGCCTGACCAGCGGCGCGATGCTCAATCGCTGGGCCGGTTGGTTTGTGCCGGTCGCAAGCAAGGTT
GTGTTAATTGGCACTGCCGAAGCGGCCAAAACTGCCCAAACCGAGCTAAGCATGATCGGCATCGACCAAATCGAAGGCTA
TATCACGCCCGATATGCTAACCGAATGGCTCAAAACCAACCCAAGCCAAAGCTATCAACGGGTGCCAGCCGCCAATTTGA
GCGAACAACTTGACCAGGCGTTTGTGCTCGATGTGCGCACGCCCGAAGAATATGCCAACGGTCACGGAGCTAAGGCGGTC
AATATTCCATTGAATGAATTACCCAAGCGCCTGGCCGAAATTCCCAATGATCAACCGTTGATCGTGCATTGTCAGGCGGG
TGGGCGTTCGCCAATTGCCATGAGTTTGCTCAAACCACATTTCAGCCAAGCCATGGTTGAGATGAGCGACGGCTGGAATG
GTTGGTATCAATTGAAAAAGGAGCGTCACGTATGA

Upstream 100 bases:

>100_bases
TGGCTTTTGCATCGCAATTCCTTAACTGCAAACCAATCCATGTAACCATTGTACAAGCAAACGCATCAAGAATATGTAAC
AGCAAAATGGAGGGTTGTCT

Downstream 100 bases:

>100_bases
TCAACGAATTAAGTGTGCAAGAACTACAAGTGTGGGCCAACCAACAAACGATCTTTTTGATCGATGTGCGTGAGCCAGCT
GAATATGCCACGGGCCATAT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MFFQRLYHDGLAQASYLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHADFVSGSRELAQITGAKLYLSA
AGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTPAGDEPMGIFTGDLLFAGDVGRPDLLE
KAAGIQGTSEAGAKDLFKSLQRIASLPDFLQVWPGHGSGSACGKALGAVPQSTLGYEKKVNWAFKQQNEADFVAAVLDGQ
PTPPPYFAAMKRINRDGPELRPQRLPALSLAEIKLDNRLVVDLRSANDFAQASIPGALSLTSGAMLNRWAGWFVPVASKV
VLIGTAEAAKTAQTELSMIGIDQIEGYITPDMLTEWLKTNPSQSYQRVPAANLSEQLDQAFVLDVRTPEEYANGHGAKAV
NIPLNELPKRLAEIPNDQPLIVHCQAGGRSPIAMSLLKPHFSQAMVEMSDGWNGWYQLKKERHV

Sequences:

>Translated_464_residues
MFFQRLYHDGLAQASYLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHADFVSGSRELAQITGAKLYLSA
AGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTPAGDEPMGIFTGDLLFAGDVGRPDLLE
KAAGIQGTSEAGAKDLFKSLQRIASLPDFLQVWPGHGSGSACGKALGAVPQSTLGYEKKVNWAFKQQNEADFVAAVLDGQ
PTPPPYFAAMKRINRDGPELRPQRLPALSLAEIKLDNRLVVDLRSANDFAQASIPGALSLTSGAMLNRWAGWFVPVASKV
VLIGTAEAAKTAQTELSMIGIDQIEGYITPDMLTEWLKTNPSQSYQRVPAANLSEQLDQAFVLDVRTPEEYANGHGAKAV
NIPLNELPKRLAEIPNDQPLIVHCQAGGRSPIAMSLLKPHFSQAMVEMSDGWNGWYQLKKERHV
>Mature_464_residues
MFFQRLYHDGLAQASYLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHADFVSGSRELAQITGAKLYLSA
AGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTPAGDEPMGIFTGDLLFAGDVGRPDLLE
KAAGIQGTSEAGAKDLFKSLQRIASLPDFLQVWPGHGSGSACGKALGAVPQSTLGYEKKVNWAFKQQNEADFVAAVLDGQ
PTPPPYFAAMKRINRDGPELRPQRLPALSLAEIKLDNRLVVDLRSANDFAQASIPGALSLTSGAMLNRWAGWFVPVASKV
VLIGTAEAAKTAQTELSMIGIDQIEGYITPDMLTEWLKTNPSQSYQRVPAANLSEQLDQAFVLDVRTPEEYANGHGAKAV
NIPLNELPKRLAEIPNDQPLIVHCQAGGRSPIAMSLLKPHFSQAMVEMSDGWNGWYQLKKERHV

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=216, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI21703352, Length=216, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI94538320, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI94538322, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI41327741, Length=184, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538952, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330176, Length=202, Percent_Identity=27.2277227722772, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356335, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24667711, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24667703, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 50245; Mature: 50245

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQRLYHDGLAQASYLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHAD
CCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCEEEEEEHHHCCEEEEEEEECCEEEH
FVSGSRELAQITGAKLYLSAAGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPG
HHCCCHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEEEEEEEEECCC
HTPEHVIFMLTDTPAGDEPMGIFTGDLLFAGDVGRPDLLEKAAGIQGTSEAGAKDLFKSL
CCCCEEEEEEECCCCCCCCCEEEECCEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHH
QRIASLPDFLQVWPGHGSGSACGKALGAVPQSTLGYEKKVNWAFKQQNEADFVAAVLDGQ
HHHHCCCHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCC
PTPPPYFAAMKRINRDGPELRPQRLPALSLAEIKLDNRLVVDLRSANDFAQASIPGALSL
CCCCHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCEEE
TSGAMLNRWAGWFVPVASKVVLIGTAEAAKTAQTELSMIGIDQIEGYITPDMLTEWLKTN
CCCHHHHHHCCHHEECCCCEEEEECCHHHHHHHHHHHEEEHHHHCCEECHHHHHHHHHCC
PSQSYQRVPAANLSEQLDQAFVLDVRTPEEYANGHGAKAVNIPLNELPKRLAEIPNDQPL
CCHHHHHCCCCCHHHHCCCEEEEEECCCHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCE
IVHCQAGGRSPIAMSLLKPHFSQAMVEMSDGWNGWYQLKKERHV
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MFFQRLYHDGLAQASYLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHAD
CCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCEEEEEEHHHCCEEEEEEEECCEEEH
FVSGSRELAQITGAKLYLSAAGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPG
HHCCCHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCEEEEEEEEEEEECCC
HTPEHVIFMLTDTPAGDEPMGIFTGDLLFAGDVGRPDLLEKAAGIQGTSEAGAKDLFKSL
CCCCEEEEEEECCCCCCCCCEEEECCEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHH
QRIASLPDFLQVWPGHGSGSACGKALGAVPQSTLGYEKKVNWAFKQQNEADFVAAVLDGQ
HHHHCCCHHHHCCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCC
PTPPPYFAAMKRINRDGPELRPQRLPALSLAEIKLDNRLVVDLRSANDFAQASIPGALSL
CCCCHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCEEE
TSGAMLNRWAGWFVPVASKVVLIGTAEAAKTAQTELSMIGIDQIEGYITPDMLTEWLKTN
CCCHHHHHHCCHHEECCCCEEEEECCHHHHHHHHHHHEEEHHHHCCEECHHHHHHHHHCC
PSQSYQRVPAANLSEQLDQAFVLDVRTPEEYANGHGAKAVNIPLNELPKRLAEIPNDQPL
CCHHHHHCCCCCHHHHCCCEEEEEECCCHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCE
IVHCQAGGRSPIAMSLLKPHFSQAMVEMSDGWNGWYQLKKERHV
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA